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Displaying 20 of 208 results for "HIPK2"
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  1. Transcription profiling of HIPK2 dominant negative mouse mutants vs wild type littermates to identify genes regulated by HIPK2 which are li... ArrayExpress

    ID: E-GEOD-2869

    Description: mbryonic stage. One of these candidate genes, the Homeodomain Interacting Protein Kinase 2 (HIPK2), is postulated to be a transcriptional coregulator, based on its in vitro interactions with repressor homeodomain proteins of the NK class, as well as other components of repressor complexes. HIPK2 has also been shown to be involved in post-translational modification of two major transcriptional regulators, p53 and CtBP. Expression of a dominant-negativ...

  2. Transcription profiling of HIPK2 dominant negative mouse mutants vs wild type littermates to identify genes regulated by HIPK2 which are li... OmicsDI

    ID: E-GEOD-2869

    Date Released: 06-10-2011

    Description: mbryonic stage. One of these candidate genes, the Homeodomain Interacting Protein Kinase 2 (HIPK2), is postulated to be a transcriptional coregulator, based on its in vitro interactions with repressor homeodomain proteins of the NK class, as well as other components of repressor complexes. HIPK2 has also been shown to be involved in post-translational modification of two major transcriptional regulators, p53 and CtBP. Expression of a dominant-negativ...

  3. Transcriptional Corepressors HIPK1 and HIPK2 Control Angiogenesis via TGF-b-TAK1-depdendent Mechanism ArrayExpress

    ID: E-GEOD-39253

    Description: is remain poorly characterized. Here we show that homeodomain interacting protein kinases, HIPK1 and HIPK2, are transcriptional corepressors that regulate TGF-b-depednent angiogenesis during embryonic development. Loss of HIPK1 and HIPK2 leads to marked up-re...

  4. Identification of Hipk2 as a central regulator of white fat development OmicsDI

    ID: E-GEOD-46077

    Date Released: 06-03-2014

    Description: Homeodomain interacting protein kinase 2 (

  5. Evaluation of HIPK2-modulated genes in cancer cells. BioProject

    ID: PRJNA144703

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Identification of Hipk2 as a central regulator of white fat development ArrayExpress

    ID: E-GEOD-46077

    Description: Homeodomain interacting protein kinase 2 (

  7. Transcriptional Corepressors HIPK1 and HIPK2 Control Angiogenesis via TGF-b-TAK1-depdendent Mechanism BioProject

    ID: PRJNA170389

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Identification of Hipk2 as an essential regulator of white fat development BioProject

    ID: PRJNA197207

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. Comprehensive expression profiling across primary fetal liver terminal erythroid differentiation ArrayExpress

    ID: E-GEOD-20391

    Description: filing Gene-targeting experiments report that the homeodomain-interacting protein kinases 1 and 2, Hipk1 and Hipk2, are essential but redundant in hematopoietic development—because Hipk1/Hipk2 double-deficient animals exhibit severe defects in hematopoiesis and vasculogenesis while the single knockouts do not. These serine-threonine kinases phosphorylate, and consequently modify the functions of, several important hematopoietic transcription factors and cofactors. Here we show that Hipk2 knockdown alone plays a significant role in terminal fetal liver erythroid differentiation. Hipk1 and Hipk2 are highly induced during primary mouse fetal liver erythropoiesis. Specific knockdown of Hipk2 inhibits terminal erythroid cell proliferation—explained in part by impaired cell cycle progression as ...

  10. Evaluation of HIPK2-modulated genes in cancer cells. OmicsDI

    ID: E-GEOD-31089

    Date Released: 01-11-2012

    Description: HIPK2, a member of the homeodomain-interacting protein kinase

  11. Murine fetal liver TER119-negative erythroid precursors: Hipk1 or Hipk2 knockdown versus control BioProject

    ID: PRJNA119787

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Rosenfeld-5R01NS034934-14 GEMMA

    ID: 15

    Keywords: functional genomics

    Description: mbryonic stage. One of these candidate genes, the Homeodomain Interacting Protein Kinase 2 (HIPK2), is postulated to be a transcriptional coregulator, based on its in vitro interactions with repressor homeodomain proteins of the NK class, as well as other components of repressor complexes. HIPK2 has also been shown to be involved in post-translational modification of two major transcriptional regulators, p53 and CtBP. Expression of a dominant-negativ...

  13. Systems approach identifies HIPK2 as a critical regulator of kidney tubulointerstitial fibrosis OmicsDI

    ID: E-GEOD-35226

    Date Released: 02-14-2012

    Description: tal systems biology approach to identify upstream protein kinases that regulate gene expression changes in kidneys of HIV-1 transgenic mice (Tg26), which have significant tubulo-interstitial fibrosis (TIF) and glomeruloscleros...

  14. Evaluation of HIPK2-modulated genes in cancer cells ArrayExpress

    ID: E-GEOD-31089

    Description: HIPK2, a member of the homeodomain-interacting protein kinase

  15. Systems approach identifies HIPK2 as a critical regulator of kidney tubulointerstitial fibrosis BioProject

    ID: PRJNA150661

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Rosenfeld-5R01NS034934-14 BioProject

    ID: PRJNA92539

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: mbryonic stage. One of these candidate genes, the Homeodomain Interacting Protein Kinase 2 (HIPK2), is postulated to be a transcriptional coregulator, based on its in vitro interactions with repressor homeodomain proteins of the NK class, as well as other components of repressor complexes. HIPK2 has also been shown to be involved in post-translational modification of two major transcriptional regulators, p53 and CtBP. Expression of a dominant-negativ...
  17. HIPK2 and MED19 are new regulators of androgen receptor in prostate cancer cells BioProject

    ID: PRJNA187993

    Keywords: Transcriptome or Gene expression

    Access Type: download

  18. Genome-wide analysis of the TEC-specific Hipk2 gene knockout in mouse medullary thymic epithelial cells (mTECs) BioProject

    ID: PRJNA267718

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. Genome-wide analysis of the TEC-specific Hipk2 gene knockout in mouse medullary thymic epithelial cells (mTECs) ArrayExpress

    ID: E-GEOD-63432

    Description: Analysis of the role of Hipk2 in regulating gene expression in medullary thymic epithelial cells. The whole genome gene signatures of purified mTEC subsets...

  20. HIPK2_MESAU UniProt:Swiss-Prot

    ID: Q9WUM7

    Description: Homeodomain-interacting protein kinase 2


Displaying 20 of 208 results for "HIPK2"