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Displaying 20 of 69 results for "HEY1"
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  1. Expression data of LPS-induced genes in bone marrow derived macrophages BioProject

    ID: PRJNA297141

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: uce expression of two Hes family members Hes1 and Hey1 in macrophages.To evaluate the effects of these two factors on inflammatory responses, we generated mice lacking both Hes1 and Hey1 (DK...
  2. Expression data of LPS-induced genes in bone marrow derived macrophages ArrayExpress

    ID: E-GEOD-73484

    Description: uce expression of two Hes family members Hes1 and Hey1 in macrophages.To evaluate the effects of these two factors on inflammatory responses, we generated mice lacking both Hes1 and Hey1 (DK...

  3. Expression data of LPS-induced genes in bone marrow derived macrophages OmicsDI

    ID: E-GEOD-73484

    Date Released: 06-18-2016

    Description: uce expression of two Hes family members Hes1 and Hey1 in macrophages.To evaluate the effects of these two factors on inflammatory responses, we generated mice lacking both Hes1 and Hey1 (DK...

  4. Hey target gene regulation in murine ES cells and cardiomyocytes [Affymetrix] OmicsDI

    ID: E-GEOD-60746

    Date Released: 01-10-2016

    Description: rdiomyocyte differentiation system with inducible Hey1 or Hey2 expression to study target gene regulation in cardiomyocytes (CM) generated from murine embryonic stem cells (ESC). The effects of

  5. Hey target gene regulation in murine ES cells and cardiomyocytes [high throughput sequencing] OmicsDI

    ID: E-GEOD-60699

    Date Released: 01-10-2016

    Description: rdiomyocyte differentiation system with inducible Hey1 or Hey2 expression to study target gene regulation in cardiomyocytes (CM) generated from murine embryonic stem cells (ESC). The effects of

  6. Hey target gene regulation in murine ES cells and cardiomyocytes [high throughput sequencing] ArrayExpress

    ID: E-GEOD-60699

    Description: rdiomyocyte differentiation system with inducible Hey1 or Hey2 expression to study target gene regulation in cardiomyocytes (CM) generated from murine embryonic stem cells (ESC). The effects of

  7. Hey target gene regulation in murine ES cells and cardiomyocytes [Affymetrix] ArrayExpress

    ID: E-GEOD-60746

    Description: rdiomyocyte differentiation system with inducible Hey1 or Hey2 expression to study target gene regulation in cardiomyocytes (CM) generated from murine embryonic stem cells (ESC). The effects of

  8. HEY1_DANRE UniProt:Swiss-Prot

    ID: Q8AXV6

    Description: Hairy/enhancer-of-split related with YRPW motif protein 1 bHLH Orange YRPW motif Poly-Gln Ser-rich

    gene.name: hey1
  9. HEY1_BOVIN UniProt:Swiss-Prot

    ID: Q2KIN4

    Description: Hairy/enhancer-of-split related with YRPW motif protein 1 bHLH Orange Transcriptional repression and interaction with NCOR1 and SIN3A YRPW motif

    gene.name: HEY1
  10. Transcription profiling of human T cell leukaemia cell line Jurkat that were retrovirally transduced with constitutievely active forms of Notch to ide... ArrayExpress

    ID: E-MEXP-1744

    Description: In this study we aimed to identify novel transcriptional targets of Notch signalling in the T cell leukaemia cell line, Jurkat. RNA was prepared from ...

  11. Hey target gene regulation in murine ES cells and cardiomyocytes [high throughput sequencing] BioProject

    ID: PRJNA259326

    Keywords: Other

    Access Type: download

    dataset.description: rdiomyocyte differentiation system with inducible Hey1 or Hey2 expression to study target gene regulation in cardiomyocytes (CM) generated from murine embryonic stem cells (ESC). The effects of
  12. Hey target gene regulation in murine ES cells and cardiomyocytes [Affymetrix] BioProject

    ID: PRJNA259416

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: rdiomyocyte differentiation system with inducible Hey1 or Hey2 expression to study target gene regulation in cardiomyocytes (CM) generated from murine embryonic stem cells (ESC). The effects of
  13. Effect of Notch1 pathway activation on high-grade glioma cells ArrayExpress

    ID: E-GEOD-44561

    Description: was activated, the typical target proteins (HES5, HEY1, HEY2) were not or barely expressed in two explored GBM stem cell cultures. Notch1 signalling activation by expression of the intracellular form (NICD) in these cells was found to reduce their growth rate and migration which was accompanied by the sharp reduction of neural stem cell transcription factor expression (ASCL1, OLIG2, SOX2) while HEY1/2, KLF9, SNAI2 transcription factors were upregulated. Expression of OLIG2 and growth were restored after termination of Notch1 stimulation. Remarkably, NICD expression induced the expression of pericyte cell markers (NG2, PDGFRb and a-smooth muscle actin (aSMA)) in GBM stem cells. This was paralleled with the induction of several angiogenesis-related factors most notably ...

  14. Identification of p130Cas/ErbB2 dependent invasive signatures in transformed mammary epithelial cells ArrayExpress

    ID: E-GEOD-43907

    Description: lity, migration (ITPKA, PRDM1), and angiogenesis (HEY1) are up-regulated while genes involved in the inflammatory response (SAA1, S100A7) are down-regulated. In parallel, we have shown that the expression of specific miRNAs is altered. Among these, mir-200b, miR-222, miR-221and miR-424 are up-regulated while miR-27a, miR-27b and miR-23b are down-regulated. Overall this study present, for the first time, gene expression changes underlying the invasive behaviour following p130Cas over-expression in an ErbB2 transformed mammary cell model. 12 samples were analyzed: 3 ErbB2, 3 Cas, 3 Cas/ErbB2, 3 Ctr MCF10A.B2...

  15. Effect of Notch1 pathway activation on high-grade glioma cells OmicsDI

    ID: E-GEOD-44561

    Date Released: 06-06-2014

    Description: was activated, the typical target proteins (HES5, HEY1, HEY2) were not or barely expressed in two explored GBM stem cell cultures. Notch1 signalling activation by expression of the intracellular form (NICD) in these cells was found to reduce their growth rate and migration which was accompanied by the sharp reduction of neural stem cell transcription factor expression (ASCL1, OLIG2, SOX2) while HEY1/2, KLF9, SNAI2 transcription factors were upregulated. Expression of OLIG2 and growth were restored after termination of Notch1 stimulation. Remarkably, NICD expression induced the expression of pericyte cell markers (NG2, PDGFRb and a-smooth muscle actin (aSMA)) in GBM stem cells. This was paralleled with the induction of several angiogenesis-related factors most notably ...

  16. Protective unfolded protein response in human pancreatic beta cells transplanted into mice BioProject

    ID: PRJNA128915

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Changes in Gene Expression Profile in two Multidrug Resistant Cell Lines derived from a same Drug Sensitive Cell line BioProject

    ID: PRJNA246521

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ffected in FEPS with overexpression of NOTCH2 and HEY1. The highly overexpressed gene in MDR cell was ABCB1, and both presented the ABCB1 promoter unmethylated. Overall design: Gene expression profiles were obtained with the GeneChip® Human Genome U133 Plus 2.0 Array (Affymetrix, Singapore) according to the manufacturer´s instructions; all hybridization experiments were carried out in duplicate. The following samples were analyzed: human K562 cell line RNA from cells grown without drugs; human Lucena 1 cell line RNA from cells grown in medium with vincristine (Lucena 1+VCR); Lucena 1 cell line RNA from cells grown in medium without drugs (Lucena 1-VCR...
  18. Transcription profiling by array of human pancreatic beta cells transplanted into mice ArrayExpress

    ID: E-GEOD-22097

    Description: Islet transplantation exposes beta cells to mild hyperglycemia and to the abnormal environment of the transplant site. These conditions may affect bet...

  19. Effect of Notch1 pathway activation on high-grade glioma cells BioProject

    ID: PRJNA190058

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: was activated, the typical target proteins (HES5, HEY1, HEY2) were not or barely expressed in two explored GBM stem cell cultures. Notch1 signalling activation by expression of the intracellular form (NICD) in these cells was found to reduce their growth rate and migration which was accompanied by the sharp reduction of neural stem cell transcription factor expression (ASCL1, OLIG2, SOX2) while HEY1/2, KLF9, SNAI2 transcription factors were upregulated. Expression of OLIG2 and growth were restored after termination of Notch1 stimulation. Remarkably, NICD expression induced the expression of pericyte cell markers (NG2, PDGFRb and a-smooth muscle actin (aSMA)) in GBM stem cells. This was paralleled with the induction of several angiogenesis-related factors most notably...
  20. Identification of p130Cas/ErbB2 dependent invasive signatures in transformed mammary epithelial cells. BioProject

    ID: PRJNA188105

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: lity, migration (ITPKA, PRDM1), and angiogenesis (HEY1) are up-regulated while genes involved in the inflammatory response (SAA1, S100A7) are down-regulated. In parallel, we have shown that the expression of specific miRNAs is altered. Among these, mir-200b, miR-222, miR-221and miR-424 are up-regulated while miR-27a, miR-27b and miR-23b are down-regulated. Overall this study present, for the first time, gene expression changes underlying the invasive behaviour following p130Cas over-expression in an ErbB2 transformed mammary cell model. Overall design: 12 samples were analyzed: 3 ErbB2, 3 Cas, 3 Cas/ErbB2, 3 Ctr MCF10A.B2...

Displaying 20 of 69 results for "HEY1"