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Displaying 20 of 27 results for "GRPR"
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  1. Amoeba sp. BB2 : Amoeba sp. BB2 Raw sequence reads BioProject

    ID: PRJNA343644

    Keywords: raw sequence reads

    Access Type: download

  2. GRPR_RAT UniProt:Swiss-Prot

    ID: P52500

    Description: Gastrin-releasing peptide receptor Extracellular Helical; Name=1 Cytoplasm...

  3. GRPR_MOUSE UniProt:Swiss-Prot

    ID: P21729

    Description: Gastrin-releasing peptide receptor Extracellular Helical; Name=1 Cytoplasm...

  4. Brucella melitensis bv. 1 strain:BB2 : Brucella melitensis BB2 Genome sequencing BioProject

    ID: PRJNA266086

    Keywords: genome sequencing

    Access Type: download

  5. plant metagenome : BB2 Metagenome BioProject

    ID: PRJNA318092

    Keywords: metagenome

    Access Type: download

  6. Designed Oligooxopiperazines as Modulators of Hypoxia-Inducible Factor Signaling BioProject

    ID: PRJNA208988

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ells were treated with transcriptional inhibitors BB2-162, BB2-125, BB2-282 or vehicle and their expression profiles were compared to normoxic A549 cells treated with vehicle....
  7. Designed Oligooxopiperazines as Modulators of Hypoxia-Inducible Factor Signaling ArrayExpress

    ID: E-GEOD-48134

    Description: ells were treated with transcriptional inhibitors BB2-162, BB2-125, BB2-282 or vehicle and their expression profiles were compared to normoxic A549 cells treated with vehicle....

  8. CIRCULARLY PERMUTED BB2-CRYSTALLIN PDB

    ID: PDB:1BD7

    Description: CIRCULARLY PERMUTED BB2-CRYSTALLIN

  9. Caenorhabditis elegans strain:N2, BB2(adr-1-/-),BB3(adr-2-/-), BB4(adr-1-/-; adr-2-/-) : Profiling of RNA editing in Caenorhabditis elegans BioProject

    ID: PRJNA215361

    Keywords: transcriptome

    Access Type: download

  10. BRS4_BOMOR UniProt:Swiss-Prot

    ID: P47751

    Description: [Phe13]-bombesin receptor Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extracellular Hel...

  11. Human induced pluripotent stem cells derived from a sporadic Alzheimer's disease patient ArrayExpress

    ID: E-GEOD-31163

    Description: noticeable differences in several genes: DNAJC15, GRPR, NAIP and SNORD116-18. Several other biomarkers were differentially expressed in AD-iPSC clones, which were implicated in memory impairment and AD. Furthermore, well characterized familial AD-associated genes (APP, PSEN1, PSEN2) and non-familial (A2M, APOE, GAP43, MAOA, MPO, PLAT, PLAU, SORL1, SNCA) exhibited different expression patterns but were largely reset upon reprogramming into a pluripotent state. Overall, hiPSCs can be good candidates for AD modeling and may represent an in vitro alternative to studying disease mechanisms and drug discovery/toxicology studies. Fibroblasts and two hiPSC clones from a non-familia...

  12. Effect of prolonged stretch on transcript profile of human pregnant myometrium BioProject

    ID: PRJNA145997

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: 5 h exposure to increased stretch. Two probes for gastrin-releasing peptide (GRP), a known stimulatory agonist of smooth muscle, were among the top five up-regulated by stretch (3.4-fold and 2.0-fold). Up-regulation of GRP by stretch was confirmed in a separate series of 10 samples using qRT-PCR (2.8-fold, P = 0.01). GRP stimulated contractions acutely when added to freshly obtained myometrial strips in 3 out of 9 cases, but Western blot demonstrated expression of the GRP receptor in 9 out of 9 cases. Prolonged incubation of stretched explants in the GRP antagonists PD-176252 or RC-3095 (65 and 24 h respectively) significantly reduced potassium chloride and oxytocin-induced contractility. Conclusion: Stretch of human myometrium increases contractility and stimulates the expression of a known smooth musc...
  13. BRS3_HUMAN UniProt:Swiss-Prot

    ID: P32247

    Description: Bombesin receptor subtype-3 Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extrace...

  14. BRS3_SHEEP UniProt:Swiss-Prot

    ID: O97967

    Description: Bombesin receptor subtype-3 Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extrace...

  15. BRS3_MACMU UniProt:Swiss-Prot

    ID: Q6H2Y3

    Description: Bombesin receptor subtype-3 Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extrace...

  16. Effect of prolonged stretch on transcript profile of human pregnant myometrium ArrayExpress

    ID: E-GEOD-31329

    Description: 5 h exposure to increased stretch. Two probes for gastrin-releasing peptide (GRP), a known stimulatory agonist of smooth muscle, were among the top five up-regulated by stretch (3.4-fold and 2.0-fold). Up-regulation of GRP by stretch was confirmed in a separate series of 10 samples using qRT-PCR (2.8-fold, P = 0.01). GRP stimulated contractions acutely when added to freshly obtained myometrial strips in 3 out of 9 cases, but Western blot demonstrated expression of the GRP receptor in 9 out of 9 cases. Prolonged incubation of stretched explants in the GRP antagonists PD-176252 or RC-3095 (65 and 24 h respectively) significantly reduced potassium chloride and oxytocin-induced contractility. Conclusion: Stretch of human myometrium increases contractility and stimulates the expression of a known smooth musc...

  17. BRS3_CAVPO UniProt:Swiss-Prot

    ID: P35371

    Description: Bombesin receptor subtype-3 Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extrace...

  18. BRS3_RAT UniProt:Swiss-Prot

    ID: Q8K418

    Description: Bombesin receptor subtype-3 Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extrace...

  19. Human induced pluripotent stem cells derived from a sporadic Alzheimer's disease patient BioProject

    ID: PRJNA144799

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: noticeable differences in several genes: DNAJC15, GRPR, NAIP and SNORD116-18. Several other biomarkers were differentially expressed in AD-iPSC clones, which were implicated in memory impairment and AD. Furthermore, well characterized familial AD-associated genes (APP, PSEN1, PSEN2) and non-familial (A2M, APOE, GAP43, MAOA, MPO, PLAT, PLAU, SORL1, SNCA) exhibited different expression patterns but were largely reset upon reprogramming into a pluripotent state. Overall, hiPSCs can be good candidates for AD modeling and may represent an in vitro alternative to studying disease mechanisms and drug discovery/toxicology studies. Overall design: Fibroblasts and two hiPSC clones fr...
  20. Effect of prolonged stretch on transcript profile of human pregnant myometrium OmicsDI

    ID: E-GEOD-31329

    Date Released: 06-26-2012

    Description: 5 h exposure to increased stretch. Two probes for gastrin-releasing peptide (GRP), a known stimulatory agonist of smooth muscle, were among the top five up-regulated by stretch (3.4-fold and 2.0-fold). Up-regulation of GRP by stretch was confirmed in a separate series of 10 samples using qRT-PCR (2.8-fold, P = 0.01). GRP stimulated contractions acutely when added to freshly obtained myometrial strips in 3 out of 9 cases, but Western blot demonstrated expression of the GRP receptor in 9 out of 9 cases. Prolonged incubation of stretched explants in the GRP antagonists PD-176252 or RC-3095 (65 and 24 h respectively) significantly reduced potassium chloride and oxytocin-induced contractility. Conclusion: Stretch of human myometrium increases contractility and stimulates the expression of a known smooth musc...


Displaying 20 of 27 results for "GRPR"