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Displaying 20 of 34 results for "GPX3"
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  1. Gpx3 male transgenic liver expression vs B6/DBA male wildtype control OmicsDI

    ID: E-GEOD-11997

    Date Released: 06-10-2011

    Description: f eight out of the nine genes, with Gas7, Me1 and Gpx3 being novel, resulted in significant changes in obesity related traits. Liver expression signatures revealed alterations in common metabolic pathways and networks contributing to abdominal obesity and overlapped with a macrophage-enriched metabolic network module that is highly associated with metabolic traits in mice and humans. Integration of gene expression in the design and analysis of traditional F2 intercross studies allows high confidence prediction of causal genes, and identification of involved pathways and networks. Keywords: Obesity study in transgenic animals A total of...

  2. Gpx3 male transgenic liver expression vs B6/DBA male wildtype control BioProject

    ID: PRJNA109239

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. High Fat Diet Reduces the Expression of Glutathione Peroxidase 3 in Mouse Prostate OmicsDI

    ID: E-GEOD-26464

    Date Released: 01-10-2012

    Description: re all differentially regulated by high fat diet. GPx3 mRNA levels were decreased by approximately 2-fold by high fat diet in all 3 prostate lobes. In human non-transformed prostate cells (PrSC, PrEC and BPH-1), cholesterol loading decreased GPx3 expression, and increased H2O2 levels of culture medium. Troglitazone increased GPx3 expression in 3 normal prostate cells, and decreased H2O2 levels. In addition, troglitazone attenuated cholesterol-induced H2O2 increase. Tissue from prostate cancer biopsies had decreased GPx3 mRNA and its level was inversely related to the Gleason score. High fat diet alters pathways related to many genes concerned with oxidative stress. GPx3, a gene identified by this analysis, was found to be down regulated by high fat diet and appears be decreased in human pro...

  4. High Fat Diet Reduces the Expression of Glutathione Peroxidase 3 in Mouse Prostate ArrayExpress

    ID: E-GEOD-26464

    Description: re all differentially regulated by high fat diet. GPx3 mRNA levels were decreased by approximately 2-fold by high fat diet in all 3 prostate lobes. In human non-transformed prostate cells (PrSC, PrEC and BPH-1), cholesterol loading decreased GPx3 expression, and increased H2O2 levels of culture medium. Troglitazone increased GPx3 expression in 3 normal prostate cells, and decreased H2O2 levels. In addition, troglitazone attenuated cholesterol-induced H2O2 increase. Tissue from prostate cancer biopsies had decreased GPx3 mRNA and its level was inversely related to the Gleason score. High fat diet alters pathways related to many genes concerned with oxidative stress. GPx3, a gene identified by this analysis, was found to be down regulated by high fat diet and appears be decreased in human pro...

  5. Gpx3 male transgenic liver expression vs B6/DBA male wildtype control ArrayExpress

    ID: E-GEOD-11997

    Description: f eight out of the nine genes, with Gas7, Me1 and Gpx3 being novel, resulted in significant changes in obesity related traits. Liver expression signatures revealed alterations in common metabolic pathways and networks contributing to abdominal obesity and overlapped with a macrophage-enriched metabolic network module that is highly associated with metabolic traits in mice and humans. Integration of gene expression in the design and analysis of traditional F2 intercross studies allows high confidence prediction of causal genes, and identification of involved pathways and networks. Keywords: Obesity study in transgenic animals A total of...

  6. High Fat Diet Reduces the Expression of Glutathione Peroxidase 3 in Mouse Prostate BioProject

    ID: PRJNA136535

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: re all differentially regulated by high fat diet. GPx3 mRNA levels were decreased by approximately 2-fold by high fat diet in all 3 prostate lobes. In human non-transformed prostate cells (PrSC, PrEC and BPH-1), cholesterol loading decreased GPx3 expression, and increased H2O2 levels of culture medium. Troglitazone increased GPx3 expression in 3 normal prostate cells, and decreased H2O2 levels. In addition, troglitazone attenuated cholesterol-induced H2O2 increase. Tissue from prostate cancer biopsies had decreased GPx3 mRNA and its level was inversely related to the Gleason score. High fat diet alters pathways related to many genes concerned with oxidative stress. GPx3, a gene identified by this analysis, was found to be down regulated by high fat diet and appears be decreased in human pro...
  7. Crystal structure of human glutathione peroxidase 3 (selenocysteine to glycine mutant) PDB

    ID: PDB:2R37

    Description: Glutathione peroxidase 3 (E.C.1.11.1.9)

    gene.name: GPX3, GPXP
  8. GPX3_PONPY UniProt:Swiss-Prot

    ID: Q5RFG3

    Description: Glutathione peroxidase 3 Selenocysteine

    gene.name: GPX3
  9. MRM analysis of serological markers for lung cancer OmicsDI

    ID: PXD004384

    Date Released: 06-20-2016

    Description: kers. Finally, two potential biomarkers (BCHE and GPX3; AUC = 0.918 and 0.728, respectively) and one two-marker panel (BCHE/GPX3; AUC = 0.943) were able to effectively differentiate NSCLC from healthy controls. Collectively, these results demonstrate that our pipeline for marker discovery and our MRM-MS platform for verifying potential biomarkers are feasible for use with human diseases....

  10. GPX3_MACFU UniProt:Swiss-Prot

    ID: Q4AEH4

    Description: Glutathione peroxidase 3 Selenocysteine

    gene.name: GPX3
  11. GPX3_HYLLA UniProt:Swiss-Prot

    ID: Q4AEH5

    Description: Glutathione peroxidase 3 Selenocysteine

    gene.name: GPX3
  12. GPX3_SAPAP UniProt:Swiss-Prot

    ID: Q4AEH3

    Description: Glutathione peroxidase 3 Selenocysteine

    gene.name: GPX3
  13. Differential genome-wide gene expression profiling of bovine largest and second largest follicles ArrayExpress

    ID: E-GEOD-18145

    Description: HA. The QPCR analysis confirmed AMH, CYP19, FSHR, GPX3, PGF, PLA2G1B, SCD and TRB2 were greater in F1 than F2, while CCL2, GADD45A, IGFBP5, PLAUR, SELP, SPP1, TIMP1 and TSP2 were greater in F2 than F1. Expression of stage-specific genes in follicles may be closely associated with its growth or atresia. Several genes identified in this study will provide intriguing candidates for the determinant of follicular growth. Global gene expression of three largest follicles and two second largest follicles were analyzed...

  14. Obesity study in transgenic and knockout animals OmicsDI

    ID: E-GEOD-12000

    Date Released: 05-01-2014

    Description: f eight out of the nine genes, with Gas7, Me1 and Gpx3 being novel, resulted in significant changes in obesity related traits. Liver expression signatures revealed alterations in common metabolic pathways and networks contributing to abdominal obesity and overlapped with a macrophage-enriched metabolic network module that is highly associated with metabolic traits in mice and humans. Integration of gene expression in the design and analysis of traditional F2 intercross studies allows high confidence prediction of causal genes, and identification of involved pathways and networks. This SuperSeries is composed of the following subset Ser...

  15. Differential genome-wide gene expression profiling of bovine largest and second largest follicles BioProject

    ID: PRJNA119475

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: HA. The QPCR analysis confirmed AMH, CYP19, FSHR, GPX3, PGF, PLA2G1B, SCD and TRB2 were greater in F1 than F2, while CCL2, GADD45A, IGFBP5, PLAUR, SELP, SPP1, TIMP1 and TSP2 were greater in F2 than F1. Expression of stage-specific genes in follicles may be closely associated with its growth or atresia. Several genes identified in this study will provide intriguing candidates for the determinant of follicular growth. Overall design: Global gene expression of three largest follicles and two second largest follicles were analyzed...
  16. Glutathione peroxidase-type tryparedoxin peroxidase, oxidized form PDB

    ID: PDB:3DWV

    Description: Glutathione peroxidase-like protein (E.C.1.11.1.9)

    gene.name: gpx3, Tb927.7.1140
  17. Obesity study in transgenic and knockout animals ArrayExpress

    ID: E-GEOD-12000

    Description: f eight out of the nine genes, with Gas7, Me1 and Gpx3 being novel, resulted in significant changes in obesity related traits. Liver expression signatures revealed alterations in common metabolic pathways and networks contributing to abdominal obesity and overlapped with a macrophage-enriched metabolic network module that is highly associated with metabolic traits in mice and humans. Integration of gene expression in the design and analysis of traditional F2 intercross studies allows high confidence prediction of causal genes, and identification of involved pathways and networks. This SuperSeries is composed of the following subset Ser...

  18. Glutathione peroxidase-type tryparedoxin peroxidase, oxidized form PDB

    ID: PDB:2RM5

    Description: Glutathione peroxidase-like protein (E.C.1.11.1.9)

    gene.name.raw: gpx3
  19. Crystal structure of glutathione-dependent phospholipid peroxidase Hyr1 from the yeast Saccharomyces cerevisiae PDB

    ID: PDB:3CMI

    Description: Peroxiredoxin HYR1 (E.C.1.11.1.15)

    gene.name: HYR1, GPX3, ORP1
  20. Glutathione peroxidase-type tryparedoxin peroxidase, reduced form PDB

    ID: PDB:2RM6

    Description: Glutathione peroxidase-like protein (E.C.1.11.1.9)

    gene.name.raw: gpx3

Displaying 20 of 34 results for "GPX3"