GPX1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 169 results for "GPX1"
i
  1. Transcriptional Regulation of the GPX1 Gene by TFAP2C and Aberrant CpG Methylation in Human Breast Cancer ArrayExpress

    ID: E-GEOD-36351

    Description: P2C in the various cell lines, we identified that glutathione peroxidase (GPX1) is regulated by TFAP2C through an AP-2 regulatory region in the promoter of the GPX1 gene. Knock-down of TFAP2C, but not the related factor TFAP2A, resulted in an abrogation of GPX1 expression. Selenium-dependent GPX activity correlated with endogenous GPX1 expression, and overexpression of exogenous GPX1 induced GPX activity and significantly increased resistance to tert-butyl hydroperoxide. Methylation of the CpG island encompassing the AP-2 regulatory region was identified in cell lines where TFAP2C failed to bind the

  2. Global transcriptomic profiling of ischemic/reperfusion injury in an in vivo Gpx1 -/- transgenic mouse model ArrayExpress

    ID: E-GEOD-23162

    Description: Glutathione peroxidase (Gpx) is a selenium-containing enzyme that catalyses the reduction of a variety of biolog...

  3. Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1 PDB

    ID: PDB:2F8A

    Description: Glutathione peroxidase 1 (E.C.1.11.1.9)

  4. Methylation of Polycomb target genes in intestinal cancer is mediated by inflammation ArrayExpress

    ID: E-GEOD-12315

    Description: Using glutathione peroxidase, Gpx1 and Gpx2, double knockout (Gpx1/2-KO) mice as...

  5. GPX1_MACFU UniProt:Swiss-Prot

    ID: Q865R2

    Description: Glutathione peroxidase 1 Subject to oxidation and hydroselenide loss to dehydroalanine Seleno...

  6. Transcriptional Regulation of the GPX1 Gene by TFAP2C and Aberrant CpG Methylation in Human Breast Cancer OmicsDI

    ID: E-GEOD-36351

    Date Released: 03-11-2013

    Description: P2C in the various cell lines, we identified that glutathione peroxidase (GPX1) is regulated by TFAP2C through an AP-2 regulatory region in the promoter of the GPX1 gene. Knock-down of TFAP2C, but not the related factor TFAP2A, resulted in an abrogation of GPX1 expression. Selenium-dependent GPX activity correlated with endogenous GPX1 expression, and overexpression of exogenous GPX1 induced GPX activity and significantly increased resistance to tert-butyl hydroperoxide. Methylation of the CpG island encompassing the AP-2 regulatory region was identified in cell lines where TFAP2C failed to bind the

  7. GPX1_SAPAP UniProt:Swiss-Prot

    ID: Q4AEI1

    Description: Glutathione peroxidase 1 Subject to oxidation and hydroselenide loss to dehydroalanine Seleno...

  8. GPX1_PIG UniProt:Swiss-Prot

    ID: Q8MJ14

    Description: Glutathione peroxidase 1 Subject to oxidation and hydroselenide loss to dehydroalanine Seleno...

  9. GPX1_PONPY UniProt:Swiss-Prot

    ID: Q4AEI3

    Description: Glutathione peroxidase 1 Subject to oxidation and hydroselenide loss to dehydroalanine Seleno...

  10. GPX1_HYLLA UniProt:Swiss-Prot

    ID: Q4AEI2

    Description: Glutathione peroxidase 1 Subject to oxidation and hydroselenide loss to dehydroalanine Seleno...

  11. Crystal structure of T. cruzi GPX1 PDB

    ID: PDB:3E0U

    Description: Glutathione peroxidase (E.C.1.11.1.9)

  12. Methylation of Polycomb target genes in intestinal cancer is mediated by inflammation BioProject

    ID: PRJNA113543

    Keywords: Epigenomics

    Access Type: download

    dataset.description: Using glutathione peroxidase, Gpx1 and Gpx2, double knockout (Gpx1/2-KO) mice as...
  13. GPX1_PANTR UniProt:Swiss-Prot

    ID: Q0EFA0

    Description: Glutathione peroxidase 1 Subject to oxidation and hydroselenide loss to dehydroalanine Seleno...

  14. GPX1_CALJA UniProt:Swiss-Prot

    ID: Q0EF99

    Description: Glutathione peroxidase 1 Subject to oxidation and hydroselenide loss to dehydroalanine Seleno...

  15. Selenium toxicity but not deficient or super-nutritional selenium status vastly alters the transcriptome in rodents BioProject

    ID: PRJNA130445

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: d mRNA levels for several selenoproteins, such as glutathione peroxidase-1 (Gpx1), are down-regulated dramatically by selenium (Se) de...
  16. Global transcriptomic profiling of ischemic/reperfusion injury in an in vivo Gpx1 -/- transgenic mouse model. BioProject

    ID: PRJNA133271

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Transcriptional Regulation of the GPX1 Gene by TFAP2C and Aberrant CpG Methylation in Human Breast Cancer BioProject

    ID: PRJNA153311

    Keywords: Epigenomics

    Access Type: download

  18. Methylation of Polycomb target genes in intestinal cancer is mediated by inflammation OmicsDI

    ID: E-GEOD-12315

    Date Released: 05-03-2014

    Description: Using glutathione peroxidase, Gpx1 and Gpx2, double knockout (Gpx1/2-KO) mice as...

  19. Global transcriptomic profiling of ischemic/reperfusion injury in an in vivo Gpx1 -/- transgenic mouse model. OmicsDI

    ID: E-GEOD-23162

    Date Released: 06-26-2012

    Description: Glutathione peroxidase (Gpx) is a selenium-containing enzyme that catalyses the reduction of a variety of biolog...

  20. Glutathione peroxidase-type tryparedoxin peroxidase, oxidized form PDB

    ID: PDB:3DWV

    Description: Glutathione peroxidase-like protein (E.C.1.11.1.9)


Displaying 20 of 169 results for "GPX1"