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Displaying 19 of 19 results for "GPR17"
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  1. FoxO1 target Gpr17 activates AgRP neurons to regulate food intake. BioProject

    ID: PRJNA196508

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. FoxO1 target Gpr17 activates AgRP neurons to regulate food intake. OmicsDI

    ID: E-GEOD-45858

    Date Released: 04-22-2013

    Description: ow-sorted FoxO1-deficient AgRP neurons identifies G-protein-coupled receptor Gpr17 as a FoxO1 target whose expression is regulated by nutritional status. Intracerebroventricular injection of Gpr17 agonists induces food intake, whereas Gpr17 antagonist cangrelor curtails it. These effects are absent in Agrp-Foxo1 knockouts, suggesting that pharmacological modulation of this pathway has therapeutic potential to treat obesity. We used microarrays to detail the change of gene expression in AgRP neurons after knocking out FoxO1. AgRP neurons from control and KO mice were collected by FACS. Gene expression was analyzed by microarray....

  3. FoxO1 target Gpr17 activates AgRP neurons to regulate food intake ArrayExpress

    ID: E-GEOD-45858

    Description: ow-sorted FoxO1-deficient AgRP neurons identifies G-protein-coupled receptor Gpr17 as a FoxO1 target whose expression is regulated by nutritional status. Intracerebroventricular injection of Gpr17 agonists induces food intake, whereas Gpr17 antagonist cangrelor curtails it. These effects are absent in Agrp-Foxo1 knockouts, suggesting that pharmacological modulation of this pathway has therapeutic potential to treat obesity. We used microarrays to detail the change of gene expression in AgRP neurons after knocking out FoxO1. AgRP neurons from control and KO mice were collected by FACS. Gene expression was analyzed by microarray....

  4. Comparison of H111 c3-null mutants R12 and R33 to wild-type ArrayExpress

    ID: E-MTAB-732

    Description: The purpose of this experiment was to determine differences in expression between wild-type B. cenocepacia H111 and two Tn5 mutants, R12 and R33, isol...

  5. ChIP-seq analysis of oligodendrocytes treated with demyelinating compound lysolecithin BioProject

    ID: PRJNA327818

    Keywords: Epigenomics

    Access Type: download

    dataset.description: demonstrated that Olig2 and its downstream target Gpr17 were the key factors functioning in demyelination process. During demyelination, Olig2 was significantly up-regulated, and Gpr17 was the top ranking Olig2...
  6. Campylobacter jejuni subsp. jejuni strain:R12 : Campylobacter jejuni subsp. jejuni strain:R12 Genome sequencing and assembly BioProject

    ID: PRJNA314584

    Keywords: genome sequencing and assembly

    Access Type: download

  7. LGR5_XENTR UniProt:Swiss-Prot

    ID: F7D3V9

    Description: Leucine-rich repeat-containing G-protein coupled receptor 5 Extracellular Helical; Name=1 Cytoplasmic Hel...

  8. LGR5_RAT UniProt:Swiss-Prot

    ID: D4AC13

    Description: Leucine-rich repeat-containing G-protein coupled receptor 5 Extracellular Helical; Name=1 Cytoplasmic Hel...

  9. LGR6_DANRE UniProt:Swiss-Prot

    ID: P0DM44

    Description: Leucine-rich repeat-containing G-protein coupled receptor 6 Helical Helical Helical Helical Helical Helic...

  10. An analysis of global gene expression reveals molecular and signalling pathways hallmarks of neural stem cell survival and expansion in response to FG... ArrayExpress

    ID: E-GEOD-37516

    Description: dhesion (Dscaml1), cell differentiation (Dscaml1, Gpr17, S100b) and signal transduction (Gpr17, Ndrg2), among others. These findings support that continuous supply of FGF-2 and EGF is critical to maintain the viability/survival of NSCs in culture and reveals novel molecular hallmarks of NSC maintenance/survival and expansion in response to these growth factors. Total RNA was extracted from aOBSC cultures using the Trizol reagent (Invitrogen) and purified with Qiagen RNeasy Mini Kit separation columns (Qiagen). The RNA was sent to the Genomic Unit of CNB (Centro Nacional de Biotecnologia, Madrid, Spain). RNA integrity was corroborated by using Bioanalyzer. Then, cDNA was synthesized and hybridized to Affymetrix GeneChip Mouse Genome 430 2.0 arrays (Affymetrix, Santa Clara, CA, ) which contain a total of 45101 transcripts to assess and compare the overall gene expression profiles. 9 samples were analyzed. Ctr: Control mouse adult olfatory bulb stem cells (aOBSC) cultured with daily added Fgf2 and Egf, 3 biological rep C2: Mouse adult olfatory bulb stem cells (aOBSC) cultured with Fgf2 and Egf added every two days, 3 biological rep C4: Mouse adult olfatory bulb stem cells (aOBSC) cultured with Fgf2 and Egf added every four days, 3 biological rep...

  11. LGR5_BOVIN UniProt:Swiss-Prot

    ID: F1MT22

    Description: Leucine-rich repeat-containing G-protein coupled receptor 5 Extracellular Helical; Name=1 Cytoplasmic Hel...

  12. LGR5A_XENLA UniProt:Swiss-Prot

    ID: E5DHB5

    Description: Leucine-rich repeat-containing G-protein coupled receptor 5A Extracellular Helical; Name=1 Cytoplasmic He...

  13. GPR98_DANRE UniProt:Swiss-Prot

    ID: Q6JAN0

    Description: G-protein coupled receptor 98 Extracellular Helical; Name=1 Cytoplasmic He...

  14. Coordinated Progression Through Two Subtranscriptomes Underlies the Tachyzoite Cycle of Toxoplasma gondii ArrayExpress

    ID: E-GEOD-19092

    Description: We describe the cell cycle transcriptome of the Toxoplasma gondii that has emerged as a major genetic model for the study of Apicomplexa parasites. T...

  15. An analysis of global gene expression reveals molecular and signalling pathways hallmarks of neural stem cell survival and expansion in response to FG... BioProject

    ID: PRJNA160975

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: dhesion (Dscaml1), cell differentiation (Dscaml1, Gpr17, S100b) and signal transduction (Gpr17, Ndrg2), among others. These findings support that continuous supply of FGF-2 and EGF is critical to maintain the viability/survival of NSCs in culture and reveals novel molecular hallmarks of NSC maintenance/survival and expansion in response to these growth factors. Total RNA was extracted from aOBSC cultures using the Trizol reagent (Invitrogen) and purified with Qiagen RNeasy Mini Kit separation columns (Qiagen). The RNA was sent to the Genomic Unit of CNB (Centro Nacional de Biotecnologia, Madrid, Spain). RNA integrity was corroborated by using Bioanalyzer. Then, cDNA was synthesized and hybridized to Affymetrix GeneChip Mouse Genome 430 2.0 arrays (Affymetrix, Santa Clara, CA, http://www.affymetrix.com) which contain a total of 45101 transcripts to assess and compare the overall gene expression profiles. Overall design: 9 samples were analyzed. Ctr: Control mouse adult olfatory bulb stem cells (aOBSC) cultured with daily added Fgf2 and Egf, 3 biological rep C2: Mouse adult olfatory bulb stem cells (aOBSC) cultured with Fgf2 and Egf added every two days, 3 biological rep C4: Mouse adult olfatory bulb stem cells (aOBSC) cultured with Fgf2 and Egf added every four days, 3 biological rep...
  16. GPR17_RAT UniProt:Swiss-Prot

    ID: Q09QM4

    Description: Uracil nucleotide/cysteinyl leukotriene receptor Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extracellular Helical; Name=3 Cytoplasmic Helical; Name=4 Extrac...

  17. Coordinated Progression Through Two Subtranscriptomes Underlies the Tachyzoite Cycle of Toxoplasma gondii BioProject

    ID: PRJNA120513

    Keywords: Transcriptome or Gene expression

    Access Type: download

  18. Crystal structure of the mu-opioid receptor bound to a morphinan antagonist PDB

    ID: PDB:4DKL

    Description: Mu-type opioid receptor, lysozyme chimera (E.C.3.2.1.17)

  19. An analysis of global gene expression reveals molecular and signalling pathways hallmarks of neural stem cell survival and expansion in response to FG... OmicsDI

    ID: E-GEOD-37516

    Date Released: 05-11-2012

    Description: dhesion (Dscaml1), cell differentiation (Dscaml1, Gpr17, S100b) and signal transduction (Gpr17, Ndrg2), among others. These findings support that continuous supply of FGF-2 and EGF is critical to maintain the viability/survival of NSCs in culture and reveals novel molecular hallmarks of NSC maintenance/survival and expansion in response to these growth factors. Total RNA was extracted from aOBSC cultures using the Trizol reagent (Invitrogen) and purified with Qiagen RNeasy Mini Kit separation columns (Qiagen). The RNA was sent to the Genomic Unit of CNB (Centro Nacional de Biotecnologia, Madrid, Spain). RNA integrity was corroborated by using Bioanalyzer. Then, cDNA was synthesized and hybridized to Affymetrix GeneChip Mouse Genome 430 2.0 arrays (Affymetrix, Santa Clara, CA, http://www.affymetrix.com) which contain a total of 45101 transcripts to assess and compare the overall gene expression profiles. 9 samples were analyzed. Ctr: Control mouse adult olfatory bulb stem cells (aOBSC) cultured with daily added Fgf2 and Egf, 3 biological rep C2: Mouse adult olfatory bulb stem cells (aOBSC) cultured with Fgf2 and Egf added every two days, 3 biological rep C4: Mouse adult olfatory bulb stem cells (aOBSC) cultured with Fgf2 and Egf added every four days, 3 biological rep...


Displaying 19 of 19 results for "GPR17"