GNL3L | bioCADDIE Data Discovery Index
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Displaying 7 of 7 results for "GNL3L"
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  1. GNL3L_BOVIN UniProt:Swiss-Prot

    ID: Q3T0J9

    Description: Guanine nucleotide-binding protein-like 3

  2. GNL3L_MOUSE UniProt:Swiss-Prot

    ID: Q6PGG6

    Description: Guanine nucleotide-binding protein-like 3

  3. GNL3L_HUMAN UniProt:Swiss-Prot

    ID: Q9NVN8

    Description: Guanine nucleotide-binding protein-like 3

  4. The gene profile of zebrafish guanine binding protein-like 2 (Gnl2) mutant embryos versus wild-type embryos at 22 hours post-fertilization BioProject

    ID: PRJNA126649

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Myc-dependent purine biosynthesis regulates the expression of oncogenes and tumour suppressors in prostate cancer cells ArrayExpress

    ID: E-GEOD-51384

    Description: triphosphate within treated cells. This imposes nucleolar stress on cells as determined by significant reductions in the levels of guanine nucleotide binding protein-like 3 (GNL3). In addition the levels of c-Myc, p53 and the androgen receptor are affected and the expression of tumour suppressive microRNA-34b is increased. Combining the IMPDH2 inhibitor with anti-androgens results in a combinatorial inhibition of cell proliferation. In conclusion we propose using enzymes within the de novo purine biosynthesis as cancer biomarkers and applying drugs to alter the flux through this pathway may represent an effective means of stratifying patients for therapy and sensitising some to AR-targeted therapies. Total RNA of three biological replicates for each condition was extracted using the RNeasy kit (Qiagen), conditions are: 5 h vehicle, 5 h Doxycycline, 12 h vehicle, 12 h Doxycyline...

  6. Myc-dependent purine biosynthesis regulates the expression of oncogenes and tumour suppressors in prostate cancer cells BioProject

    ID: PRJNA222856

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: triphosphate within treated cells. This imposes nucleolar stress on cells as determined by significant reductions in the levels of guanine nucleotide binding protein-like 3 (GNL3). In addition the levels of c-Myc, p53 and the androgen receptor are affected and the expression of tumour suppressive microRNA-34b is increased. Combining the IMPDH2 inhibitor with anti-androgens results in a combinatorial inhibition of cell proliferation. In conclusion we propose using enzymes within the de novo purine biosynthesis as cancer biomarkers and applying drugs to alter the flux through this pathway may represent an effective means of stratifying patients for therapy and sensitising some to AR-targeted therapies. Overall design: Total RNA of three biological replicates for each condition was extracted using the RNeasy kit (Qiagen), conditions are: 5 h vehicle, 5 h Doxycycline, 12 h vehicle, 12 h Doxycyline...
  7. Myc-dependent purine biosynthesis regulates the expression of oncogenes and tumour suppressors in prostate cancer cells OmicsDI

    ID: E-GEOD-51384

    Date Released: 03-18-2016

    Description: triphosphate within treated cells. This imposes nucleolar stress on cells as determined by significant reductions in the levels of guanine nucleotide binding protein-like 3 (GNL3). In addition the levels of c-Myc, p53 and the androgen receptor are affected and the expression of tumour suppressive microRNA-34b is increased. Combining the IMPDH2 inhibitor with anti-androgens results in a combinatorial inhibition of cell proliferation. In conclusion we propose using enzymes within the de novo purine biosynthesis as cancer biomarkers and applying drugs to alter the flux through this pathway may represent an effective means of stratifying patients for therapy and sensitising some to AR-targeted therapies. Total RNA of three biological replicates for each condition was extracted using the RNeasy kit (Qiagen), conditions are: 5 h vehicle, 5 h Doxycycline, 12 h vehicle, 12 h Doxycyline...


Displaying 7 of 7 results for "GNL3L"