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Displaying 20 of 428 results for "GNAQ"
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  1. eal melanoma cell lines with wild type and mutant G-proteins (GNAQ or GNA11) in response to treatment with BRAD4 inhibitor JQ1... ArrayExpress

    ID: E-GEOD-66048

    Description: G protein alpha q and 11 are mutated in 80% of uveal melanoma. We observed...

  2. eal melanoma cell lines with wild type and mutant G-proteins (GNAQ or GNA11) in response to treatment with BRAD4 inhibitor JQ1... OmicsDI

    ID: E-GEOD-66048

    Date Released: 04-30-2015

    Description: G protein alpha q and 11 are mutated in 80% of uveal melanoma. We observed...

  3. GNAQ_CANLF UniProt:Swiss-Prot

    ID: Q28294

    Description: Guanine nucleotide-binding protein G(q

  4. Genome sequencing coupled with iPSC technology identifies GTDC1 as a novel candidate gene involved in Neurodevelopmental Disorders ArrayExpress

    ID: E-GEOD-51430

    Description: d to the identification of seven disrupted genes (GNAQ, RBFOX3, UNC5D, TMEM47, NCAPG2, GTDC1 and XIAP). For one patient we filtered the entire panel of structural variations (SVs) with his parents and identified a unique SV that disrupted a single gene: GTDC1. We then validated the functional consequences of the chromosomal breakpoint disruption of GTDC1 by using patient-derived iPSCs. By differentiating these cells into neural progenitor cells (NPCs) and...

  5. GNAQ_XENLA UniProt:Swiss-Prot

    ID: P38410

    Description: Guanine nucleotide-binding protein G(q

  6. GNAQ_RAT UniProt:Swiss-Prot

    ID: P82471

    Description: Guanine nucleotide-binding protein G(q

  7. GNAQ_PIG UniProt:Swiss-Prot

    ID: Q2PKF4

    Description: Guanine nucleotide-binding protein G(q

  8. Genomic variant detection in Uveal Melanoma : Identification of genomic variants associated with Uveal Melanoma by exome sequencing of a patient and c... BioProject

    ID: PRJEB4578

    Keywords: Other

    Access Type: download

    dataset.description: ons, putatively causal for UM, were identified in GNAQ, SF3B1 and SOX10. Somatic mutations in GNAQ and SF3B1 genes were probable drivers of UM in the Indian patient, as were also earlier reported in some Caucasian patients. In addition, a novel frame shift deletion in exon 4 of the SOX10 gene, which encodes a transcription factor that acts upstream of Microphthalmia-associated transcription factor (MITF) and synergizes with MITF, reportedly have an essential role in melanocyte development and pigmentation, likely plays a role in the development and progression of UM....
  9. Crystal structure of activated G alpha Q bound to its effector phospholipase C beta 3 PDB

    ID: PDB:3OHM

    Description: Guanine nucleotide-binding protein G(q

  10. Crystal structure of Galphaq in complex with full-length human PLCbeta3 PDB

    ID: PDB:4GNK

    Description: Guanine nucleotide-binding protein G(q

  11. Structure of human regulator of G protein signaling 2 (RGS2) in complex with murine Galpha-q(R183C) PDB

    ID: PDB:4EKD

    Description: Guanine nucleotide-binding protein G(q

  12. Structure of regulator of G protein signaling 8 (RGS8) in complex with AlF4-activated Galpha-q PDB

    ID: PDB:5DO9

    Description: Guanine nucleotide-binding protein G(q

  13. Structure of human regulator of G protein signaling 2 (RGS2) in complex with murine Galpha-q(R183C) PDB

    ID: PDB:4EKC

    Description: Guanine nucleotide-binding protein G(q

  14. Crystal Structure of p63RhoGEF complex with Galpha-q and RhoA PDB

    ID: PDB:2RGN

    Description: Guanine nucleotide-binding protein G(q

  15. Genome sequencing coupled with iPSC technology identifies GTDC1 as a novel candidate gene involved in Neurodevelopmental Disorders BioProject

    ID: PRJNA223164

    Keywords: Variation

    Access Type: download

    dataset.description: d to the identification of seven disrupted genes (GNAQ, RBFOX3, UNC5D, TMEM47, NCAPG2, GTDC1 and XIAP). For one patient we filtered the entire panel of structural variations (SVs) with his parents and identified a unique SV that disrupted a single gene: GTDC1. We then validated the functional consequences of the chromosomal breakpoint disruption of GTDC1 by using patient-derived iPSCs. By differentiating these cells into neural progenitor cells (NPCs) and...
  16. Structure of a fragment of human phospholipase C-beta3 delta472-569, bound to IP3 and in complex with Galphaq PDB

    ID: PDB:4QJ4

    Description: Guanine nucleotide-binding protein G(q

  17. Structure of a fragment of human phospholipase C-beta3 delta472-559, in complex with Galphaq PDB

    ID: PDB:4QJ3

    Description: Guanine nucleotide-binding protein G(q

  18. Structure of a fragment of human phospholipase C-beta3 delta472-581, bound to IP3 and in complex with Galphaq PDB

    ID: PDB:4QJ5

    Description: Guanine nucleotide-binding protein G(q

  19. Crystal Structure of G Protein-Coupled Receptor Kinase 2 in Complex with Galpha-q and Gbetagamma Subunits PDB

    ID: PDB:2BCJ

    Description: G-protein coupled receptor kinase 2 (E.C.2.7.1.126), Guanine nucleotide-

  20. ARHGP_RAT UniProt:Swiss-Prot

    ID: Q6P720

    Description: Rho guanine nucleotide exchange factor 25 DH PH Important for binding to Rho GTPases Sufficient t...


Displaying 20 of 428 results for "GNAQ"