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Displaying 20 of 51 results for "GET4"
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  1. WFUBMC Primate Center X-96-23: Cynomolgus macaque response to hormone replacement therapy BioProject

    ID: PRJNA137499

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: X-96-23 had 5 groups. Each of 4 groups had a different treatment type and there was also a control group. A total of 16 samples was sent for micro array analysis...
  2. The novel SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity PDB

    ID: PDB:5CPR

    Description: Histone-lysine N-methyltransferase SUV420H1 (E.C.2.1.1.43)

  3. DNA methylation analysis of prostate cancer cell lines and tissues using Next Generation Sequencing ArrayExpress

    ID: E-GEOD-27618

    Description: cer tissues were comparable. While approximately 20% of all CpG islands (CGIs) (68,508) were methylated in tissues, promoter CGI methylation gradually increased from ~12.6% in benign samples to 19.3% and 21.8% in localized and metastatic cancer tissues. We found distinct patterns in promoter methylation around transcription start sites, where methylation occurred directly on the CGIs, flanking regions and on CGI sparse promoters. Among the 6,691 methylated promoters in prostate tissues, 2481 differentially methylated regions (DMRs) are cancer specific and several previously studied targets were among them. A novel cancer specific DMR in WFDC2 promoter showed 77% methylation in cancer ...

  4. Methylation profiling in pediatric medulloblastoma BioProject

    ID: PRJNA95829

    Keywords: Epigenomics

    Access Type: download

    dataset.description: sitively digested DNA (Cy5) from the same sample. CGI methylation in 20 pediatric medulloblastomas (M) and normal cerebellum (Cb, pool of five unaffected donors, age 25–33 years)...
  5. GET4_XENTR UniProt:Swiss-Prot

    ID: A4QNE0

    Description: Golgi to ER traffic protein 4 homolog

  6. ReducedRepresentation : Focussing reduced representation CpG sequencing through judicious restriction enzyme choice BioProject

    ID: PRJEB12622

    Keywords: Other

    Access Type: download

    dataset.description: ed, but unbiased, methylome coverage. Since only ~20% of CpGs are dynamically regulated, we characterised the CpG and genomic context surrounding all suitable restriction enzyme sites to identify those that were located in regions rich in dynamically methylated CpGs. The...
  7. MPC_ Deep Sequencing Reveals Distinct Pattern of DNA Methylation in Prostate Cancer BioProject

    ID: PRJNA188782

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: cent and cancer tissues were comparable. Promoter CGI methylation gradually increased from -12.6% in benign samples to 19.3% and 21.8% in localized and metastatic cancer tissues and approximately 20% of all CpG islands (CGIs) (68,508) were methylated in tissues. We observed distinct patterns in promoter methylation around transcription start sites, where methylation occurred directly... (for more see dbGaP study page.)...
  8. Solution structure of the Get5 carboxyl domain from S. cerevisiae PDB

    ID: PDB:2LNZ

    Description: Ubiquitin-like protein MDY2

  9. Crystal structure of the Get5 carboxyl domain from S. cerevisiae PDB

    ID: PDB:3VEJ

    Description: Ubiquitin-like protein MDY2

  10. Evolution of a highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor PDB

    ID: PDB:2P4I

    Description: Tie-2 Kinase

    dataset.creators: Bellon, S.
  11. Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors PDB

    ID: PDB:2OO8

    Description: Tie-2

    dataset.creators: Bellon, S.
  12. Crystal structure of human Pim-1 kinase in complex with a thiadiazolamine-indole inhibitor. PDB

    ID: PDB:4WT6

    Description: Serine/threonine protein kinase pim-1 (E.C.2.7.11.1)

  13. Crystal structure of human Pim-1 kinase in complex with an azaspiro pyrazinyl-indazole inhibitor. PDB

    ID: PDB:4WRS

    Description: Serine/threonine-protein kinase pim-1 (E.C.2.7.11.1)

  14. Zea mays subsp. mays : Zea mays subsp. mays Raw sequence reads BioProject

    ID: PRJNA288155

    Keywords: raw sequence reads

    Access Type: download

    dataset.description: ize genome is relatively large (~2.3Gb) and has a complex organization of interspersed genes and transposable elements which necessities frequent boundaries between different types of chr...
  15. Methylation profiling in pediatric medulloblastoma OmicsDI

    ID: E-GEOD-4857

    Date Released: 03-27-2012

    Description: sitively digested DNA (Cy5) from the same sample. CGI methylation in 20 pediatric medulloblastomas (M) and normal cerebellum (Cb, pool of five unaffected donors, age 25–33 years)...

  16. DNA methylation analysis of prostate cancer cell lines and tissues using Next Generation Sequencing OmicsDI

    ID: E-GEOD-27618

    Date Released: 08-22-2013

    Description: cer tissues were comparable. While approximately 20% of all CpG islands (CGIs) (68,508) were methylated in tissues, promoter CGI methylation gradually increased from ~12.6% in benign samples to 19.3% and 21.8% in localized and metastatic cancer tissues. We found distinct patterns in promoter methylation around transcription start sites, where methylation occurred directly on the CGIs, flanking regions and on CGI sparse promoters. Among the 6,691 methylated promoters in prostate tissues, 2481 differentially methylated regions (DMRs) are cancer specific and several previously studied targets were among them. A novel cancer specific DMR in WFDC2 promoter showed 77% methylation in cancer (17/22), 100% methylation in transform...

  17. Women's Health Initiative dbGaP

    ID: phs000200.v10.p3

    Description: The Women's Health Initiative (WHI) is a long-term national health study that has focused on strategies for preventing heart disease, breast ...

  18. Whole Genome Sequencing of Triple Negative Breast Cancer dbGaP

    ID: phs000245.v1.p1

    Description: ding, RNA, or splice site sequences. Of these, 20 mutations were abundantly present in all three tumors, including mutations in CSMD1 and JAK2. These two genes subsequently were found to be mutated in other breast tumors. The metastasis contained two de novo mutations not present in the primary tumor, and was significantly enriched for 20 shared mutations, suggesting that they may be involved in the metastatic process. The xenograft contained no unique coding, RNA, or splice site mutations and retained all primary tumor mutations, albeit at different frequencies. However, a significant increase in copy number alterations was observed in the xenograft as compared to the primary tumor. We validated 28 large deletions and six inversions, as well as seven translocations ...

  19. AtT 20 endogenous peptides ProteomeXchange

    ID: PXD000186

    Instrument: LTQ Orbitrap

    Date Released: 06-09-2014

  20. Transcriptome analysis of two clonally-derived ICC progenitor cell lines [array] OmicsDI

    ID: E-GEOD-60744

    Date Released: 02-27-2016

    Description: CPM containing 5% cell-free chick embryo extract (CEE; Accurate Chemical). Long-term culturing of both cell lines was associated with further decline in Kit expression while expression of Ano1 and other markers of ICC precursors was maintained. Following spontaneous transformation, both 2xSCS70 and 2xSCS2F10 cells grafted into nude mice gave rise to tumors containing Kit(+)cells and otherwise resembling gastrointestinal stromal tumors (GIST), which originate from the ICC lineage (Bardsley et al., Gastroenterology 2010;139:942-952). This study utilized oligonucleotide microarray analysis to charaterize the transcriptome of non-transformed 2xSCS70 and 2xSCS2F10 cells relative to their source tissues. Total RNA from ICC progenitor cell lines and their source tissue (gastric tunica muscularis from C57BL/6J mice (source of 2xSCS2F10 cells) and H-2Kb-tsA58 mice (source of 2xSCS70 cells) was isolated. Oligonucleotide micorarray studies were performed using 2-3 Affymetrix Mouse Genome 430.2 GeneChips per sample....


Displaying 20 of 51 results for "GET4"