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Displaying 20 of 4,602 results for "GDF15"
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  1. The TGF-b superfamily cytokine GDF15 is a CCN2-regulated autocrine/paracrine factor in the heart BioProject

    ID: PRJNA239002

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Profiling of growth and differentiation factor 15 regulated genes in hepatoma cells BioProject

    ID: PRJNA134131

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Profiling of growth and differentiation factor 15 regulated genes in hepatoma cells ArrayExpress

    ID: E-GEOD-25397

    Description: To systematically profile the GDF15-regulated genes in hepatoma cells and to elucidate the possible role of GDF15 on biological processes, hig...

  4. RNA-seq of GDF15 or TGF-β stimulated NIH3T3 fibroblasts. BioProject

    ID: PRJNA270663

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. GDF15 overexpression dreived from tumor-associated macrophages and cancer cells in the microenvironment of human esophageal squamou... ArrayExpress

    ID: E-GEOD-59948

    Description: NA microarray. Based on the result, we focused on growth differentiation factor 15 (GDF15) among highly expressed genes including IL-6, IL-8 and CXCL1. Immunohistochemical study on 70 cases of surgically resected ESCCs revealed that GDF15 was detected not only in macrophages but also in cancer cells. High expression of GDF15 in ESCCs was significantly correlated with more malignant phenotypes including lymph and blood vessel invasion, lymph node metastasis as well as clinical stages. Patients with high expression of GDF15 showed poor disease-free survival (p = 0.011) and overall survival (p = 0.041). Furthermore, we found that recombinant human GDF15 promote cell proliferation and phosphorylation of both Akt and Erk1/2 in ESCC cell lines in vitro. These results indicate that

  6. GDF15 overexpression dreived from tumor-associated macrophages and cancer cells in the microenvironment of human esophageal squamou... BioProject

    ID: PRJNA257147

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Human intestinal epithelial cells: Control vs. MIC-1 Transfected BioProject

    ID: PRJNA325628

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Serum levels of human MIC-1/GDF15 vary in a diurnal pattern, do not display a profile suggestive of a satiety factor and are related to BMI Figshare

    ID: doi:10.6084/M9.FIGSHARE.1443588

    Release Date: 06-10-2015

    Description:

  9. Serum levels of human MIC-1/GDF15 vary in a diurnal pattern, do not display a profile suggestive of a satiety factor and are related to BMI Figshare

    ID: doi:10.6084/M9.FIGSHARE.1443588.V1

    Release Date: 01-19-2016

    Description:

  10. Profiling of growth and differentiation factor 15 regulated genes in hepatoma cells OmicsDI

    ID: E-GEOD-25397

    Date Released: 05-02-2014

    Description: To systematically profile the GDF15-regulated genes in hepatoma cells and to elucidate the possible role of GDF15 on biological processes, hig...

  11. Serum levels of human MIC-1/GDF15 vary in a diurnal pattern, do not display a profile suggestive of a satiety factor and are related to BMI Figshare

    ID: doi:10.6084/M9.FIGSHARE.1443589

    Release Date: 06-10-2015

    Description:

  12. Serum levels of human MIC-1/GDF15 vary in a diurnal pattern, do not display a profile suggestive of a satiety factor and are related to BMI Figshare

    ID: doi:10.6084/M9.FIGSHARE.1443589.V1

    Release Date: 01-19-2016

    Description:

  13. GDF15 overexpression dreived from tumor-associated macrophages and cancer cells in the microenvironment of human esophageal squamou... OmicsDI

    ID: E-GEOD-59948

    Date Released: 08-09-2014

    Description: NA microarray. Based on the result, we focused on growth differentiation factor 15 (GDF15) among highly expressed genes including IL-6, IL-8 and CXCL1. Immunohistochemical study on 70 cases of surgically resected ESCCs revealed that GDF15 was detected not only in macrophages but also in cancer cells. High expression of GDF15 in ESCCs was significantly correlated with more malignant phenotypes including lymph and blood vessel invasion, lymph node metastasis as well as clinical stages. Patients with high expression of GDF15 showed poor disease-free survival (p = 0.011) and overall survival (p = 0.041). Furthermore, we found that recombinant human GDF15 promote cell proliferation and phosphorylation of both Akt and Erk1/2 in ESCC cell lines in vitro. These results indicate that

  14. Expression data from MAP3K11/GDF15 axis is a critical driver of cancer cachexia BioProject

    ID: PRJNA281929

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. HIP1 mediates prostate carcinogenesis and progression through STAT3 signalling ArrayExpress

    ID: E-GEOD-35211

    Description: h fibroblast transformation, increasing grades of prostate cancer (CaP), and biochemical relapse. Here we demonstrate cellular transformation and phenotypic effects of HIP1 overexpression in a benign prostate...

  16. Gene expression profiles of HMEC-1 after exposure to the chemotherapeutic drugs bleomycin and cisplatin with untreated samples as control BioProject

    ID: PRJNA264363

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Expression data from MAP3K11/GDF15 axis is a critical driver of cancer cachexia ArrayExpress

    ID: E-GEOD-68162

    Description: potential tumor maintenance genes to drive tumor growth in vivo using a directed complementation (DC) approach. This assay involves testing the ability of an introduced gene to maintain tumor growth when expression of an inducible driving oncogene is tu...

  18. GDF15_RAT UniProt:Swiss-Prot

    ID: Q9Z0J6

    Description: Growth/differentiation factor 15 N-linked (GlcNAc...) Interchain

  19. IMR90 bystander experiment 0.5 Gy alpha particle ArrayExpress

    ID: E-GEOD-18760

    Description: expression profiles of matrix metalloproteinases 1 and 3 (MMP1 and MMP3), chemokine ligands 2, 3 and 5 (CXCL2, CXCL3 and CXCL5), interleukins 1a, 1b, 6 and 33 (IL1A, IL1B, IL6 and IL33) growth differentiation factor 15 (GDF15) and superoxide dismutase2 (SOD2) by real time quantitative PCR. These encode proteins involved in cellular signaling via the NFkappaB pathway and time course of mRNA levels revealed an increased response at 30 minutes after irradiation followed by another wave at 4 to 6 hours. We also investigated protein modifications in the AKT-GSK-3 signaling pathway and found that in irradiated cells AKT and GSK3beta are hyper-phosphorylated at 30 minutes and this effect is maintained until 4 hours after exposure. In bystanders there is a similar response with a delay of 30 minutes. In irradiated cells, inactivated GSK3beta led to decreased phosphorylation of beta-catenin. Our results are the first to show that the radiation induced bystander sign...

  20. HIP1 mediates prostate carcinogenesis and progression through STAT3 signalling BioProject

    ID: PRJNA150877

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 20 of 4,602 results for "GDF15"