GCLC | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 342 results for "GCLC"
i
  1. PRJNA343315 BioProject

    Keywords: raw sequence reads

    Access Type: download

    dataset.description: ere, we overexpressed pro-longevity gene encoding glutamate-cysteine ligase catalytic subunit (Gclc) and analyzed age-dependent changes in transcriptome that associated with the longevity, stress resistance, locomotor activity, circadian rhythmicity, and fer...
  2. Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanis... ArrayExpress

    ID: E-GEOD-2565

    Description: ransferase alpha-2, glutathione peroxidase 2, and glutamate-cysteine ligase, catalytic subunit (also known as γ-glutamyl cysteine synthetase). This is in agreement with previous observations describing changes in redox enzyme activity after phosgene exposure. We are also investigating other pathways that are responsive to phosgene exposure to identify mechanisms of toxicity and potential therapeutic targets.,Male CD-1 mice were exposed to air or 32 mg per cubic meter phosgene for 20 min and tissue collected at 30 min, 1 hr, 4 hr, 8 hr, 12 hr, 24 hr, 48 hr, or 72 hr before collection and analysis of lung tissue using oligonucleotide microarrays.,Keyword=phosgene,Keyword=mouse,Keyword=lung,Keyword=carbonyl chloride...

  3. Phosgene exposure in the mouse lung GEMMA

    ID: 1507

    Keywords: functional genomics

    Description: ransferase alpha-2, glutathione peroxidase 2, and glutamate-cysteine ligase, catalytic subunit (also known as ?-glutamyl cysteine synthetase). This is in agreement with previous observations describing changes in redox enzyme activity after phosgene exposure. We are also investigating other pathways that are responsive to phosgene exposure to identify mechanisms of toxicity and potential therapeutic targets. Male CD-1 mice were exposed to air or 32 mg per cubic meter phosgene for 20 min and tissue collected at 30 min, 1 hr, 4 hr, 8 hr, 12 hr, 24 hr, 48 hr, or 72 hr before collection and analysis of lung tissue using oligonucleotide microarrays. Last Updated (by provider): Oct 17 2005 Contributers: Theodore S Moran Alfred M Sciuito James F Dillman L D Orzolek Christopher S Phillips Alison I Hege Includes GDS1244. Update date: Sep 02 2005. Dataset description GDS1244: Analysis of lungs exposed to the toxic industrial compound carbonyl chloride (phosgene). Phosgene exposure results in pulmonary edema and acute lung injury. Lungs examined at several time points up to 72 hours after exposure. Provides insight into molecular events affected in phosgene-injured lungs.....

  4. Phosgene exposure in the mouse lung BioProject

    ID: PRJNA91969

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ransferase alpha-2, glutathione peroxidase 2, and glutamate-cysteine ligase, catalytic subunit (also known as γ-glutamyl cysteine synthetase). This is in agreement with previous observations describing changes in redox enzyme activity after phosgene exposure. We are also investigating other pathways that are responsive to phosgene exposure to identify mechanisms of toxicity and potential therapeutic targets. Male CD-1 mice were exposed to air or 32 mg per cubic meter phosgene for 20 min and tissue collected at 30 min, 1 hr, 4 hr, 8 hr, 12 hr, 24 hr, 48 hr, or 72 hr before collection and analysis of lung tissue using oligonucleotide microarrays. Keyword=phosgene Keyword=mouse Keyword=lung Keyword=carbonyl chloride Keywords: ordered...
  5. GSH1_RAT UniProt:Swiss-Prot

    ID: P19468

    Description: Glutamate--cysteine ligase catalytic subunit N-acetylme...

  6. Genome-wide map of BACH1 binding in HEK 293T cells ArrayExpress

    ID: E-GEOD-28051

    Description: 1, FTL, FTH1, ME1, SLC48A1) and redox regulation (GCLC, GCLM, SLC7A11), we also discovered BACH1 target genes effecting cell cycle and apoptosis pathways (ITPR2, CALM1, SQSTM1, TFE3, EWSR1, CDK6, BCL2L11, MAFG) as well as subcellular transport processes (CLSTN1, PSAP, MAPT, vault RNA). The newly identified impact of BACH1 on genes involved in neurodegenerative processes and proliferation provides an interesting basis for future dissection of BACH1-mediated gene repression in neurodegeneration and virus-induced cancerogenesis. Examination of BACH1 binding in HEK 293T cells by chromatin immunoprecipitation-sequencing (CHIP-seq) with input DNA as control....

  7. ESM 1 - AFM Data Dryad

    DateIssued: 04-29-2016

    Description: Contains calculated Young's moduli from brains assayed in this study. Each sheet represents a different brain. From each brain, 5 slices were taken (l...

  8. Ottowia beijingensis strain:GCS-AN-3 : Ottowia sp. GCS-AN-3 Genome Sequencing BioProject

    ID: PRJNA170397

    Keywords: Genome sequencing

    Access Type: download

  9. Genome-wide map of BACH1 binding in HEK 293T cells BioProject

    ID: PRJNA143131

    Keywords: Epigenomics

    Access Type: download

    dataset.description: 1, FTL, FTH1, ME1, SLC48A1) and redox regulation (GCLC, GCLM, SLC7A11), we also discovered BACH1 target genes effecting cell cycle and apoptosis pathways (ITPR2, CALM1, SQSTM1, TFE3, EWSR1, CDK6, BCL2L11, MAFG) as well as subcellular transport processes (CLSTN1, PSAP, MAPT, vault RNA). The newly identified impact of BACH1 on genes involved in neurodegenerative processes and proliferation provides an interesting basis for future dissection of BACH1-mediated gene repression in neurodegeneration and virus-induced cancerogenesis. Overall design: Examination of BACH1 binding in HEK 293T cells by chromatin immunoprecipitation-sequencing (CHIP-seq) with input DNA as control....
  10. Pseudopedobacter beijingensis strain:GCS-AE-31 : Pedobacter sp. GCS-AE-31 Genome Sequencing BioProject

    ID: PRJNA170396

    Keywords: Genome sequencing

    Access Type: download

  11. rhizosphere metagenome : Global studies on bacterial diversity in response to gamma-caprolactone BioProject

    ID: PRJNA196890

    Keywords: targeted loci

    Access Type: download

  12. Transcription profiling of lung from mouse exposed to carbonyl chloride (phosgene) for different lengths of time to investigate the molecular mechanis... OmicsDI

    ID: E-GEOD-2565

    Date Released: 09-16-2015

    Description: ransferase alpha-2, glutathione peroxidase 2, and glutamate-cysteine ligase, catalytic subunit (also known as γ-glutamyl cysteine synthetase). This is in agreement with previous observations describing changes in redox enzyme activity after phosgene exposure. We are also investigating other pathways that are responsive to phosgene exposure to identify mechanisms of toxicity and potential therapeutic targets.,Male CD-1 mice were exposed to air or 32 mg per cubic meter phosgene for 20 min and tissue collected at 30 min, 1 hr, 4 hr, 8 hr, 12 hr, 24 hr, 48 hr, or 72 hr before collection and analysis of lung tissue using oligonucleotide microarrays.,Keyword=phosgene,Keyword=mouse,Keyword=lung,Keyword=carbonyl chloride...

  13. ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-133,450 (SOT PHE GLY+SCC GCL) PDB

    ID: PDB:1EPQ

    Description: ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) (E.C.3.4.23.22) COMPLEXED WITH PD-133,450 (SOT PHE GLY+SCC GCL)

    material.name: CYSTEINE
  14. Expression data of LCM-dissected retina layers BioProject

    ID: PRJNA125525

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. uitment in primary human ovarian granulosa cells (GCs) transduced with androgen receptor (AR) alternative splice variant (ASV)... BioProject

    ID: PRJNA253042

    Keywords: Epigenomics

    Access Type: download

  16. Genome-wide map of BACH1 binding in HEK 293T cells OmicsDI

    ID: E-GEOD-28051

    Date Released: 06-02-2014

    Description: 1, FTL, FTH1, ME1, SLC48A1) and redox regulation (GCLC, GCLM, SLC7A11), we also discovered BACH1 target genes effecting cell cycle and apoptosis pathways (ITPR2, CALM1, SQSTM1, TFE3, EWSR1, CDK6, BCL2L11, MAFG) as well as subcellular transport processes (CLSTN1, PSAP, MAPT, vault RNA). The newly identified impact of BACH1 on genes involved in neurodegenerative processes and proliferation provides an interesting basis for future dissection of BACH1-mediated gene repression in neurodegeneration and virus-induced cancerogenesis. Examination of BACH1 binding in HEK 293T cells by chromatin immunoprecipitation-sequencing (CHIP-seq) with input DNA as control....

  17. CXBPublish-10670 GeneNetwork

    ID: CXBPublish-10670

    Description: 52 CA(1-2-3)-P/GCL-P

  18. CXBPublish-10669 GeneNetwork

    ID: CXBPublish-10669

    Description: 51 CA3T-CA1T-SL/GCL-TT-SL

  19. Effects of Glucocorticoids in Epidermal Keratinocytes OmicsDI

    ID: E-GEOD-26487

    Date Released: 06-26-2012

    Description: Glucocorticoids (GCs) have a long history of use as therapeutic agents for numerous skin diseases. Surprisingly, their specific molecular effects ar...

  20. Effects of Glucocorticoids in Epidermal Keratinocytes ArrayExpress

    ID: E-GEOD-26487

    Description: Glucocorticoids (GCs) have a long history of use as therapeutic agents for numerous skin diseases. Surprisingly, their specific molecular effects ar...


Displaying 20 of 342 results for "GCLC"