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Displaying 14 of 14 results for "FZD8"
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  1. Homo sapiens : Homo sapiens Transcriptome or Gene expression BioProject

    ID: PRJNA358477

    Keywords: transcriptome

    Access Type: download

    dataset.description: Analysis of PC-3 prostate cancer cells in FZD8 knockdown or overexpression. Results provide insight into the role of FZD8 in the prostate cancer....
  2. FZD8_RAT UniProt:Swiss-Prot

    ID: Q498S8

    Description: Frizzled-8 Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extracellular Helical; Name=3 Cytoplasmic H...

  3. FZD8_HUMAN UniProt:Swiss-Prot

    ID: Q9H461

    Description: Frizzled-8 Extracellular Helical; Name=1 Cytoplasmic Helical; Name=2 Extracellular Helical; Name=3 Cytoplasmic H...

  4. MMTV tumor and host cells ArrayExpress

    ID: E-GEOD-27540

    Description: (GFP- cells). Wnt Fzd 6hrs group: Wnt inhibitor (Fzd8-CRD) treated tumor RNA which will give some clue for direct Wnt target genes only in tumor cells. GFP- Tumor cells (4 biological replicates) and Wnt-inhibitor treated cells (5 biological replicates)...

  5. MMTV tumor and host cells OmicsDI

    ID: E-GEOD-27540

    Date Released: 05-03-2014

    Description: (GFP- cells). Wnt Fzd 6hrs group: Wnt inhibitor (Fzd8-CRD) treated tumor RNA which will give some clue for direct Wnt target genes only in tumor cells. GFP- Tumor cells (4 biological replicates) and Wnt-inhibitor treated cells (5 biological replicates)...

  6. CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MOUSE FRIZZLED 8 (MFZ8) PDB

    ID: PDB:1IJY

    Description: FRIZZLED HOMOLOG 8

  7. Crystal structure of XWnt8 in complex with the cysteine-rich domain of Frizzled 8 PDB

    ID: PDB:4F0A

    Description: Frizzled 8 cysteine-rich domain from Mus musculus, Wnt8 from Xenopus laevis

  8. Frizzled-8 complex with designed surrogate Wnt agonist, crystal form 1 PDB

    ID: PDB:5UN5

    Description: Frizzled-8, Designed Wnt agonist B12

  9. Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset PDB

    ID: PDB:5UN6

    Description: Frizzled-8, Designed Wnt agonist B12

  10. MMTV tumor and host cells BioProject

    ID: PRJNA138559

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: (GFP- cells). Wnt Fzd 6hrs group: Wnt inhibitor (Fzd8-CRD) treated tumor RNA which will give some clue for direct Wnt target genes only in tumor cells. Overall design: GFP- Tumor cells (4 biological replicates) and Wnt-inhibitor treated cells (5 biological replicates)...
  11. Additional file 7: of The human disease network in terms of dysfunctional regulatory mechanisms Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3609011_D2

    Release Date: 12-14-2016

    Description: FZD8, FOXN1 and TLE2 -centered differentially coexpressed links of Allergic asthma, Type 2 diabetes and Chronic kidney disease. (XL...

  12. Human myometrial adaptation to pregnancy BioProject

    ID: PRJNA92629

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: bitor type 1 (PAI-1), milk fat globule-EGF factor 8 protein (MFGE8), secreted frizzled-related protein 4 (sFRP4) and estrogen receptor {alpha} (ER{alpha}). On the microarray these transcripts were up-regulated 7.5-fold for PAI-1 and 4.9-fold for MFGE8 in pregnant myometrium, and down-regulated 3.7-fold for sFRP4 and 2.9-fold for ER{alpha} in pregnancy. Northern blot analyses confirmed these changes. Our findings suggest that microarray technology is a useful tool for examining global changes in gene expression that occur as the myometrium differentiates from non-pregnant to pregnant status. Defining these changes provides new insight into the structural and functional adaptations of human myometrium during pregnancy. Keywords: other Overall design: RNA isolated from a total of 14 samples of non-pregnant myometrium and four samples of pregnant myometrium was analysed using a genomic expression microarray (GEM)....
  13. Transcription profiling of mouse kidney from FGF23, TG and WT mice ArrayExpress

    ID: E-GEOD-6979

    Description: tho gene, a suggested crucial co-factor for FGF23 receptor binding and activation, was the most affected decreased gene. However, other genes proposed to regulate Pi levels, such as secreted Frizzled Related Protein 4 (sFRP4), Na+/H+ exchanger regulatory factor 1 (NHERF1) and the FGF-receptors 1-4, revealed no changes. Interestingly, expression levels of inflammatory response genes were increased and histological analysis revealed tubular nephropathy in the TG mice kidneys. In conclusion, FGF23 TG mice have altered kidney gene expression levels of several genes thought to be part of Pi homeostasis and an increase in inflammatory response genes, data supported by histological analysis. These findings may lead to further understanding of how FGF23 mediates its actions on renal Pi regulation. Experiment Overall Design: Five kidn...

  14. Gene expression analysis of Kidneys from FGF23 TG and WT mice BioProject

    ID: PRJNA99287

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: tho gene, a suggested crucial co-factor for FGF23 receptor binding and activation, was the most affected decreased gene. However, other genes proposed to regulate Pi levels, such as secreted Frizzled Related Protein 4 (sFRP4), Na+/H+ exchanger regulatory factor 1 (NHERF1) and the FGF-receptors 1-4, revealed no changes. Interestingly, expression levels of inflammatory response genes were increased and histological analysis revealed tubular nephropathy in the TG mice kidneys. In conclusion, FGF23 TG mice have altered kidney gene expression levels of several genes thought to be part of Pi homeostasis and an increase in inflammatory response genes, data supported by histological analysis. These findings may lead to further understanding of how FGF23 mediates its actions on renal Pi regulation. Keywords: Genetic Modification Overa...

Displaying 14 of 14 results for "FZD8"