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Displaying 20 of 2,361 results for "FRZB"
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  1. Gene expression in articular cartilage - subchondral bone of FRZB knockout mice ArrayExpress

    ID: E-GEOD-33656

    Description: bone of the tibial plateau from mice deficient in frizzled related protein (Frzb) compared to wild-type mice by transcriptome analysis. Methods : Gene-expression analysis of the articular cartilage and subc...

  2. Secreted frizzled related protein 3 (SFRP3) is required for tumorigenesis of PAX3-FOXO1-positive alveolar rhabdomyosarcoma ArrayExpress

    ID: E-GEOD-67999

    Description: . The majority of aRMS tumors express the fusion protein PAX3-FOXO1 (PF), which has proven chemically intractable. As such, we identified proteins downstream from or cooperate with PF to support tumorigenesis, including SFRP3 (FRZB). Suppres...

  3. Secreted frizzled related protein 3 (SFRP3) is required for tumorigenesis of PAX3-FOXO1-positive alveolar rhabdomyosarcoma BioProject

    ID: PRJNA281475

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. FRZB_MYXXA UniProt:Swiss-Prot

    ID: P43499

    Description: Frizzy aggregation protein FrzB

  5. Secreted frizzled related protein 3 (SFRP3) is required for tumorigenesis of PAX3-FOXO1-positive alveolar rhabdomyosarcoma OmicsDI

    ID: E-GEOD-67999

    Date Released: 12-12-2015

    Description: . The majority of aRMS tumors express the fusion protein PAX3-FOXO1 (PF), which has proven chemically intractable. As such, we identified proteins downstream from or cooperate with PF to support tumorigenesis, including SFRP3 (FRZB). Suppres...

  6. Gene expression in articular cartilage - subchondral bone of FRZB knockout mice OmicsDI

    ID: E-GEOD-33656

    Date Released: 01-23-2012

    Description: bone of the tibial plateau from mice deficient in frizzled related protein (Frzb) compared to wild-type mice by transcriptome analysis. Methods : Gene-expression analysis of the articular cartilage and subc...

  7. Gene expression in articular cartilage - subchondral bone of FRZB knockout mice BioProject

    ID: PRJNA148643

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. rev fritz 10031_appendix Dryad

    DateIssued: 10-29-2015

    Description: Data from sieve analyses of faeces from mammals, reptiles and birds (mean particles sizes) (captive wild animals)

  9. R script for calculating D Dryad

    DateIssued: 06-08-2015

    Description: calculates Fritz & Purvis's D for successional habitat specialization at each site and for the entire phylogeny used in this study

  10. RNA in Trypanosoma brucei heat shock granules BioProject

    ID: PRJEB12996

    Keywords: Other

    Access Type: download

    dataset.description: T bruce were heat shocked for 1 h at 41°C then granules were prepared as per Fritz et al. 2015. After spinning down cytoskeletons with trappe...
  11. RNA in Trypanosoma brucei heat shock granules ArrayExpress

    ID: E-MTAB-4557

    Description: T bruce were heat shocked for 1 h at 41C then granules were prepared as per Fritz et al. 2015. After spinning down cytoskeletons with trapped ...

  12. Global spatial ranges of zoonotic bat viruses Dryad

    DateIssued: 01-12-2016

    Description: iations. Original host distributions sourced from Fritz and Purvis 2010. Shapefiles follow projection 'long-lat' using WGS-1984 co-ordinate system. Created using package 'PBSmapping' in R version 3.1.1....

  13. Myelodysplastic syndrome marrow stroma shows widespread aberrant hypermethylation that is abrogated by treatment with DNMT inhibitors ArrayExpress

    ID: E-GEOD-60233

    Description: sregulated in MDS stroma, and the WNT antagonists FRZB and SFRP1 were aberrantly hypermethylated and underexpressed. These epigenetic changes were validated ina co-culture model of stroma and leukemic cells and in an independent set of MDS samples. Importantly, 5-Aza treatment of MDS stroma enhanced hematopoietic activity and erythroid differentiationfrom co-cultured healthy CD34+ cells. These results reveal widespread aberrant epigenetic changes in the MDS marrow microenvironment and demonstrate that DNA methyl transferase inhibitors alter the epigenomic profiles of stromal cells, potentiallycontributing to theirtherapeutic efficacy. The study population consisted of 6 MDS patients and 3 healthy controls. Individual HpaII restriction digest profiles were compared to an internal MspI digest control, to yield differentially methylated fragments for every sample....

  14. Pelomedusa_Supporting-Information_Table_S1 Dryad

    DateIssued: 05-27-2014

    Description: lineages sensu Vargas-Ramírez et al. (2010) and Fritz et al. (2014) indicated....

  15. Gene expression profiles from joint-matched macroscopically intact and OA affected cartilage of patients undergoing joint replacement surgery due to e... ArrayExpress

    ID: E-GEOD-57218

    Description: olved in skeletal development (e.g. TNFRSF11B and FRZB). Also several inflammatory genes such as CD55, PTGES and TNFAIP6, previously identified in within-joint analyses as well as in analyses comparing preserved cartilage from OA affected joints versus healthy cartilage were among the top genes. A notable new gene was NGF, highly up-regulated in OA cartilage. To identify gene expression profiles associated with OA processes in articular cartilage and determine pathways responsive to the disease process gene e...

  16. Dictyostelium fasciculatum : Dictyostelium fasciculatum SH3 genome sequencing project BioProject

    ID: PRJNA193617

    Keywords: RefSeq Genome sequencing and assembly

    Access Type: download

    dataset.description: /DDBJ by the Leibniz Institute for Age Research - Fritz Lipmann Institute....
  17. Polysphondylium pallidum PN500 : Reference genome sequence BioProject

    ID: PRJNA46447

    Keywords: RefSeq Genome sequencing and assembly

    Access Type: download

    dataset.description: DBJ by the - Leibniz Institute for Age Research - Fritz Lipmann Institute. For additional information, please see the RefSeq Chapter in the NCBI Handbook....
  18. Transduction signaling signature of Wilms tumor revealed by parallel analysis of kidney differentiation ArrayExpress

    ID: E-GEOD-25965

    Description: ed in WT. PAX2, FZD10, SHPK, WNT5B, FZD2, CRABP2, FRZB, GRK7, TESK1, HDGF and IGF2 were up- and MAPK9, PIK3CA, FRAT2, ITPR3, CDH6, HIPK1 and TIMP3 were down-regulated in WT respectively. Hierarchical clustering based on the expression of this gene set grouped DK from both species, human and mouse, and discriminated them from fetal kidney and WT in human, and the earliest kidney stages in mouse, validating the model proposed by this study and reveling a transduction signaling signature of WT. High robustness of this data was detected since expression level was tested by quantitative RT-PCR in the initial and independent sample set, with 75 and 56% of agreement. Agreement of 62% was also observed in protein level assessing blastemal component of an independent group of 137 WT. Protein expression of CRABP2, IGF2, GRK7, TESK1, HDGF, WNT5B, FZD2 and TIMP3 was also characterized in human fetal kidneys revealing interesting aspects of kidney differentiation. This study identified key genes modulated during kidney differentiation which may play a determinant role for WT onset. As far as we know, FZD10, FRZB, HDGF, MAPK9, FRAT2, SHPK, WNT5B, GRK7, TESK1, HDGF, PIK3CA, ITPR3, HIPK1 and TIMP3 were not previously associated to WT. The strong connection be...

  19. FoxO3 modulates endothelial gene expression and function by direct and indirect mechanisms ArrayExpress

    ID: E-GEOD-16573

    Description: binding to a FoxO-responsive DNA binding element (FRE). Here we explored the relative contribution of those mechanisms by comparing the transcriptional responses to conditional activation of FoxO3 and a corresponding FRE-binding mutant in primary human endothelial cells. Microarray analysis revealed several functional gene clusters regulated in absence of an intact DNA-binding domain. Notably, both mutants triggered apoptosis albeit with different efficiencies. This was associated with regulation of ...

  20. Human iPSCs derived under feeder free conditions displays an unqiue cell cycle and DNA replication genotype ArrayExpress

    ID: E-GEOD-21655

    Description: pluripotent gene expression (OCT4, NANOG, SOX2), protein expression (OCT4, NANOG, SSEA4, TRA160) and differentiation capabilities. We conducted a whole genomic transcript analysis using Affymetrix Human Gene 1.0 ST arrays to elucidate the important differences between traditional feeder-derived iPSCs and feeder-free derived iPSCs. We reveal that feeder-free iPSCs have over-represented terms belonging to DNA replication and cell cycle genes which are lacking in feeder-derived iPSCs. Feeder-free iPSCs are in many aspects more similar to hESCs including; apoptosis, chromatin modification enzymes and mitochondrial energy metabolism. We have also identified potential biomarkers for fully reprogrammed iPSCs (FRZB) and partially reprogrammed iPSCs (POTEG, MX2) based on their expr...


Displaying 20 of 2,361 results for "FRZB"