FOSL1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 324 results for "FOSL1"
i
  1. Transcription profiling of rat RK3E cells overexpressing activated TrkB following retroviral silencing of Fra-1 ArrayExpress

    ID: E-NCMF-20

    Description: Silencing of Fra-1 in RK3E cells overexpressing activated TrkB

  2. Effects of hepatocyte-restricted Fra-1 overexpression on hepatic gene expression in High-fat diet (HFD) fed mice BioProject

    ID: PRJNA227334

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Effects of hepatocyte-restricted Fra-1 overexpression on hepatic gene expression BioProject

    ID: PRJNA227329

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Comparative analysis of gene expression in Fra-1+/+ and Fra-1-/- mice lung BioProject

    ID: PRJNA187066

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival BioProject

    ID: PRJNA285461

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Comparative analysis of gene expression in Fra-1+/+ and Fra-1-/- mice lung ArrayExpress

    ID: E-GEOD-43695

    Description: We hypothesized that gene expression in lungs of Fra-1+/+ and Fra-1-/- mice are divergent thus contributing fibrosis. More ...

  7. Transcriptome profiling of control and FOSL1 knockdown Rcho-1 trophoblast stem (TS) cells BioProject

    ID: PRJNA282343

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Transcriptome profiling of control and FOSL1 knockdown Rcho-1 trophoblast stem (TS) cells ArrayExpress

    ID: E-GEOD-68272

    Description: ctions, such as invasive and endocrine phenotype. FOSL1 has been identified as a key regulator for trophoblast differentiation. We used microarray to detail mechanisms underlying FOSL1 signaling pathway in trophoblast differentiation. 3 replicates of differentiated Rcho1 T...

  9. Transcriptome profiling of control and FOSL1 knockdown Rcho-1 trophoblast stem (TS) cells OmicsDI

    ID: E-GEOD-68272

    Date Released: 08-19-2015

    Description: ctions, such as invasive and endocrine phenotype. FOSL1 has been identified as a key regulator for trophoblast differentiation. We used microarray to detail mechanisms underlying FOSL1 signaling pathway in trophoblast differentiation. 3 replicates of differentiated Rcho1 T...

  10. Insights into the invasiveness of triple negative breast cancer from genome-wide profiling of transcription factor AP-1 (expression) BioProject

    ID: PRJNA200345

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Insights into the invasiveness of triple negative breast cancer from genome-wide profiling of transcription factor AP-1 (ChIP-seq) BioProject

    ID: PRJNA197435

    Keywords: Epigenomics

    Access Type: download

  12. FOSL1 as a candidate target gene for 11q12 rearrangements in desmoplastic fibroblastoma BioProject

    ID: PRJNA150791

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. Expression profiling of lung tissue from 6-, 10- and 14-week-old Fra2 transgenic male mice ArrayExpress

    ID: E-GEOD-23745

    Description: The transcription factor complex AP-1 (Activator protein 1) is composed of Jun (c-Jun, JunB, JunD) and Fos proteins (c-<

  14. Transcription profling by array of murine pancreatic cancer cells treated with Fosl1 siRNA or control siRNA ArrayExpress

    ID: E-MTAB-4299

    Description: ocarcinoma cells (PDACs) is characterized by high Fosl1 expression and Fosl1 is linked to the control of pro-inflammatory pathways and growth of PDAC cells. To mimick the human disease in mice (> 90% of...

  15. Insights into the invasiveness of triple negative breast cancer from genome-wide profiling of transcription factor AP-1 (expression) ArrayExpress

    ID: E-GEOD-46440

    Description: TNBC remain largely unknown. We find that the AP-1 transcription factor component, Fra-1, is overexpressed in basal-like breast tumors, and its expression level has high prognostic significance. Depletion of Fra-1 or its heterodimeric partner c-Jun inhibits the proli...

  16. FOSL1 as a candidate target gene for 11q12 rearrangements in desmoplastic fibroblastoma OmicsDI

    ID: E-GEOD-35162

    Date Released: 05-14-2012

    Description: oblastoma (DF) and histologically similar tumors. FOSL1 is identified as a candidate target gene for the 11q12 rearrangments in DF. RNA was extracted from 3 frozen desmoplastic fibroblastoma (DF) biopsies and hybridized onto Affymetr...

  17. Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] BioProject

    ID: PRJNA376601

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: previously reported that the transcription factor Fra-1 not only has an essential role in breast cancer, but also drives the expression of a highly prognostic gene set. Here, we systematically perturbed the function of 31 individual Fra-1-dependent poor-prognosis genes and examined their impact on breast cancer growth in vivo. Because of the considerable number of genes in this gene set, we anticipated that the contribution of single genes to breast cancer progression would be limited. In contrast, we find that stable shRNA depletion of each...
  18. Expression profiling of lung tissue from 6-, 10- and 14-week-old Fra2 transgenic male mice BioProject

    ID: PRJNA130757

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: The transcription factor complex AP-1 (Activator protein 1) is composed of Jun (c-Jun, JunB, JunD) and Fos proteins (c-<
  19. FOSL1 as a candidate target gene for 11q12 rearrangements in desmoplastic fibroblastoma ArrayExpress

    ID: E-GEOD-35162

    Description: oblastoma (DF) and histologically similar tumors. FOSL1 is identified as a candidate target gene for the 11q12 rearrangments in DF. RNA was extracted from 3 frozen desmoplastic fibroblastoma (DF) biopsies and hybridized onto Affymetr...

  20. Transcription profiling of prostate cancer cells with Akt activation ArrayExpress

    ID: E-SMDB-2030

    Description: e inhibitor. One of the identified induced mRNAs, Fra-1, was further studied by transient transfections of a reporter construct containing its 5' regulatory region. This construct was found to be directly induced 4- to 5-fold by co-transfection with constitutively active Akt3 but not kinase dead Akt. The regulation by Akt3 was found to be due to two specific regions in the Fra-1 regulatory sequence which match Sp1 consensus sites. Finally, gel shift studies showed that the binding of Sp1 to one of these sites was dependent on the PI 3-kinase pathway. These results indicate that LY294002 treatment and washout is a useful method to study the activation of Akt in the context of a tumor cell. Moreover, the identification of


Displaying 20 of 324 results for "FOSL1"