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Displaying 20 of 76 results for "FLG"
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  1. inra12-01_mut-flg-FLG-OoPTIMICE BioProject

    ID: PRJNA197385

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. PRJNA360024 BioProject

    Keywords: raw sequence reads

    Access Type: download

    dataset.description: The filaggrin gene (FLG) is essential for skin differentiation and epidermal barrier formation with links to skin diseases, however it has a highly rep...
  3. Zymogen-FLG of the onconase PDB

    ID: PDB:2LT5

    Description: Protein P-30 (E.C.3.1.27.-)

  4. Transcriptome responses to combined biotic and abiotic stresses in Arabidopsis thaliana ArrayExpress

    ID: E-GEOD-41935

    Description: Salt+Heat, Salt+HL, Cold+HL, Heat+HL, as well as FLG (Flagellin, flg22 peptide), Cold+FLG, Heat+FLG...

  5. PRJEB1477 BioProject

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Common loss-of-function variants in FLG encoding the epidermal barrier protein filaggrin are major drivers of atopic dermatitis (AD). Support for inherited skin barrie...
  6. Transcriptome responses to combined biotic and abiotic stresses in Arabidopsis thaliana OmicsDI

    ID: E-GEOD-41935

    Date Released: 02-11-2013

    Description: Salt+Heat, Salt+HL, Cold+HL, Heat+HL, as well as FLG (Flagellin, flg22 peptide), Cold+FLG, Heat+FLG...

  7. Human gene 1.0 ST AD/IV Gene expression ArrayExpress

    ID: E-MTAB-768

    Description: ed to healthy control skin depending on filaggrin(FLG) genotype...

  8. PRJEB11661 BioProject

    Keywords: Other

    Access Type: download

    dataset.description: IV patients had homo- or heterozygous filaggrin (FLG) null alleles (loss-of-function mutation), and the additional existence of atopic dermatitis (AD) was diagnosed. Multiplex 454 pyrosequencing of V3 and V4 hyper-variable regions of cutaneous bacterial 16S rRNA was used to define skin microbial communities....
  9. FILA_MOUSE UniProt:Swiss-Prot

    ID: P11088

    Description: Filaggrin

    gene.name: Flg
  10. Transcriptional responses of Fusarium graminearum when exposed to bacterial MAMPs BioProject

    ID: PRJNA273653

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Associated Molecular Pattern) such as Flagellin (FLG), Lipooligosacharides (LOS) and Peptidoglycans (PGN) and water was used as the control. The results showed that the fungus reacts to the presence of MAMPs within hours and that the 3 MAMPs up-regulated a set of common genes. These significantly up-regulated common genes can be classified into categories such as energy generation, amino acid metabolism, iron uptake, secondary metabolism and transporters related to secondary metabolism. Analysis of the transcriptional reponse from FLG showed that the MAMP which was obtained comercially ...
  11. PRJEB18560 BioProject

    Keywords: Other

    Access Type: download

    dataset.description: c diseases, disease severity, and filaggrin gene (FLG) mutations are examined in AD patients. Methods: 101 adult AD patients were included in the study. Bacterial swabs were taken from lesional skin, non-lesional skin and nose. Swabs positive for S. aureus were characterized by spa and the respective clonal complex (CC) type assigned. Patients were characterized with respect to disease severity (SCORAD) and FLG mutations. Results: 73% of the patients were colonized with S. aureus. No specific bacterial lineage was linked to dis...
  12. Transcriptome responses to combined biotic and abiotic stresses in Arabidopsis thaliana BioProject

    ID: PRJNA178543

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Salt+Heat, Salt+HL, Cold+HL, Heat+HL, as well as FLG (Flagellin, flg22 peptide), Cold+FLG, Heat+FLG...
  13. Major differences between human atopic dermatitis and murine models as determined by global genomic profiling BioProject

    ID: PRJNA321115

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ed models were groupe 1 (Lesional: Flaky tail and FLG mutant; Control: C57BL/6NCrSlc), Group 2 (Lesional: NC/Nga(+mite); Control: NC/Nga(-mite)), Group 3 (Lesional: OVA-ODT 24h; Control: C57BL/6NCrSlc), and Group 4 (Lesional: OXA 2h; Control: BALB/c,Acetone). Overall design: Expression profiles for mice with five murine models were contrasted to their respective controls....
  14. ZNF750 Drives Terminal Epidermal Differentiation via Induction of Klf4 ArrayExpress

    ID: E-GEOD-32685

    Description: utated in numerous human skin diseases, including FLG, LOR, LCE3B, ALOXE3, and SPINK5. ZNF750 potently induced progenitor differentiation via an evolutionarily conserved C2H2 zinc finger motif. The epidermal master regulator, p63, bound the ZNF750 promoter and was necessary for its induction. ZNF750 restored differentiation to p63-deficient tissue, suggesting it acts downstream of p63. A search for functionally important ZNF750 targets via analysis of ZNF750-regulated g...

  15. ZNF750 in late keratinocyte differentiation ArrayExpress

    ID: E-GEOD-38039

    Description: iation complex and skin barrier formation such as FLG, LOR, SPINK5, ALOX12B and DSG1, known to be mutated in various human skin diseases. Furthermore, ZNF750 over-expression in undifferentiated cells induced terminal differentiation genes. Thus, ZNF750 is a regulator of keratinocyte terminal differnetiation, and with its downstream targets can serve in future elucidation of therapeutics for common disease of skin barrier Gene expression analysis: To determine the differentaition signature for HaCaT keratinocytes, with ZNF750 gene silencing, total RNA was isolated in biologic triplicates from cells induced to differentiate for twelve days and hybridized to Affymerix Human Gene 1.0 ST arrays....

  16. Analysis of flg22-induced transcriptional changes in mpk3, mpk4 and mpk6 mutants. - 2 weeks old seedlings compared for transcriptome after a 30min moc... ArrayExpress

    ID: E-GEOD-52587

    Description: inra12-05_mut_flg_ii-FLG-MPKs ra12-05_mut_flg_ii - inra12-05_mut_flg_ii - Analysis of flg22-induced transcriptional changes in mpk3, mpk4 and mpk6 mutan...

  17. Human gene 1.0 ST AD/IV Gene expression OmicsDI

    ID: E-MTAB-768

    Date Released: 01-25-2012

    Description: ed to healthy control skin depending on filaggrin(FLG) genotype...

  18. IL-22 down-regulates filaggrin expression and affects expression of profilaggrin processing enzymes by keratinocytes ArrayExpress

    ID: E-GEOD-28158

    Description: Genome-wide analysis of gene expression after stimulation with cytokines to assess the main processes, molecular functions and cellular components aff...

  19. IL-17 downregulates filaggrin and affects epidermal barrier function gene expression; potential role in the pathogenesis of atopic eczema ArrayExpress

    ID: E-GEOD-27533

    Description: Genome-wide analysis of gene expression after stimulation with cytokines to assess the main processes, molecular functions and cellular components aff...

  20. Transcription profiling by array of Arabidopsis after treatment with LPS, HrpZ, Flg-22 and NPP1 OmicsDI

    ID: E-GEOD-5615

    Date Released: 04-30-2015

    Description: AtGenExpress: A multinational coordinated effort to uncover the transcriptome of the multicellular model organism Arabidopsis thaliana (Hybridisation...


Displaying 20 of 76 results for "FLG"