EIF2AK4 | bioCADDIE Data Discovery Index
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Displaying 20 of 32 results for "EIF2AK4"
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  1. Activation of GCN2 by Ribosome Stalling Links Translation Elongation with Translation Initiation BioProject

    ID: PRJNA317428

    Access Type: download

  2. Crystal structure of the C-terminal regulatory domain of murine GCN2 PDB

    ID: PDB:4OTN

    Description: Eukaryotic translation initiation factor 2-alpha kinase 4 (E.C.2.7.11.1)

    gene.name: Eif2ak4, Gcn2, Kiaa1338
  3. Activation of GCN2 by Ribosome Stalling Links Translation Elongation with Translation Initiation ArrayExpress

    ID: E-GEOD-79930

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  4. Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type Complexed with ATP. PDB

    ID: PDB:1ZYD

    Description: Serine/threonine-protein kinase GCN2 (E.C.2.7.1.37)

  5. Crystal Structure of eIF2alpha Protein Kinase GCN2: Wild-Type in Apo Form. PDB

    ID: PDB:1ZYC

    Description: Serine/threonine-protein kinase GCN2 (E.C.2.7.1.37)

  6. Crystal Structure of eIF2alpha Protein Kinase GCN2: D835N Inactivating Mutant in Apo Form PDB

    ID: PDB:1ZXE

    Description: GCN2 protein kinase domain with D835N inactivating mutation.

  7. Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant in Apo Form. PDB

    ID: PDB:1ZY4

    Description: Serine/threonine-protein kinase GCN2 (E.C.2.7.1.37)

  8. gcn2/WT polysome loading and transcript level in Arabidopsis thaliana BioProject

    ID: PRJNA226718

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. Solution Structure of RWD/GI domain of Saccharomyces cerevisiae GCN2 PDB

    ID: PDB:2YZ0

    Description: Serine/threonine-protein kinase GCN2 (E.C.2.7.11.1)

  10. Crystal Structure of eIF2alpha Protein Kinase GCN2: R794G Hyperactivating Mutant Complexed with AMPPNP. PDB

    ID: PDB:1ZY5

    Description: Serine/threonine-protein kinase GCN2 (E.C.2.7.1.37)

  11. Crystal structure of the C-terminal domain from yeast GCN2 PDB

    ID: PDB:4OTM

    Description: Serine/threonine-protein kinase GCN2 (E.C.2.7.11.1)

  12. Selective control of metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae ArrayExpress

    ID: E-GEOD-22452

    Description: When eukaryotic cells are deprived of amino acids, uncharged tRNAs accumulate and activate the conserved GCN2 protein kinase. We examine how yeast gro...

  13. Transcription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/- ArrayExpress

    ID: E-GEOD-79929

    Description: Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation ...

  14. Examination of gene expression in cerebellum and hippocampus for mouse C57BL/6J WT and nmf205-/- ArrayExpress

    ID: E-GEOD-79926

    Description: Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation ...

  15. Temporally defined neocortical translation and polysome assembly is determined by the RNA-binding protein, Hu antigen R ArrayExpress

    ID: E-GEOD-50809

    Description: ith polysomes depends on the eIF2 alpha kinase 4 (eIF2ak4), which associated with HuR in prenatal developing neocortices. Finally, we found that deletion of HuR prior to embryonic day 10 (E10) disrupts both neocortical lamination and formation of the main neocortical commissure, the corpus callosum. Our study identifies a crucial role for HuR in neocortical development as a translational gatekeeper for functionally related mRNA subgroups and polysomal protein specificity. Cortex was dissected from mouse pups at embryonic day 13 (E13) or the day of birth (P0)....

  16. Response to herbicide treatment in wild type and gcn2 at the transcription and translation level in Arabidopsis thaliana BioProject

    ID: PRJNA226723

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Selective control of metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae BioProject

    ID: PRJNA128539

    Keywords: Transcriptome or Gene expression

    Access Type: download

  18. Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli... Figshare

    ID: doi:10.6084/M9.FIGSHARE.3118507.V1

    Release Date: 03-17-2016

    Description:

  19. Activation of the Integrated Stress Response by a Jumonji Histone Demethylase Inhibitor Induces Pro-Apoptotic Metabolic Reprogramming in Multiple Myel... ArrayExpress

    ID: E-GEOD-60626

    Description: Regulation of gene expression by chromatin modification through methylation of histone lysine residues is a dynamic, reversible process that when dere...

  20. Transcription profiling of mouse liver to assess the translational response following activation of GCN2 versus PERK - super series ArrayExpress

    ID: E-GEOD-11685

    Description: In eukaryotes, regulation of mRNA translation enables a fast, localized and finely tuned expression of gene products. Within the translation process,...


Displaying 20 of 32 results for "EIF2AK4"