EDAR | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 3 of 3 results for "EDAR"
  1. EDAD_MOUSE UniProt:Swiss-Prot

    ID: Q8VHX2

    Description: Ectodysplasin-A receptor-associated adapter protein Death Reduces binding to EDAR (in Ref. 2)

  2. Data from: Detecting genomic signatures of natural selection with principal component analysis: application to the 1000 Genomes data Dryad

    DateIssued: 03-03-2016

    Description: rovide well-known targets for positive selection (EDAR, SLC24A5, SLC45A2, DARC), and also new candidate genes (APPBPP2, TP1A1, RTTN, KCNMA, MYO5C) and noncoding RNAs. In addition to identifying genes involved in biological adaptation, we identify two biological pathways involved in polygenic adaptation that are related to the innate immune system (beta defensins) and to lipid metabolism (fatty acid omega oxidation). An additional analysis of European data shows that a genome scan based on PCA retrieves classical examples of local adaptation even when there are no well-defined populations. PCA-based statistics, implemented in the PCAdapt R package and the PCAdapt fast open-source software, retrieve well-known signals of human adaptation, which is encouraging for future whole-genome sequencing project, especially when defining populations is difficult....

  3. Transcription profiling of Strongyloides ratti larval stage 2 (L2) direct vs indirect development ArrayExpress

    ID: E-MEXP-709

    Description: S. ratti Isofemale line ED321 Heterogonic predominantly undergoes indirect development; isofemale line ED5 Homogonic predominantly undergoes direct de...

Displaying 3 of 3 results for "EDAR"