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Displaying 19 of 19 results for "DVL2"
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  1. DIX domain of human Dvl2 PDB

    ID: PDB:4WIP

    Description: human Dvl2 DIX domain

  2. The Dvl2 PDZ Domain in Complex with the C1 Inhibitory Peptide PDB

    ID: PDB:3CBX

    Description: The Dvl2 PDZ Domain in Complex with a Phage-Derived C-terminal Peptide (C1)

  3. The Dvl2 PDZ Domain in Complex with the N1 Inhibitory Peptide PDB

    ID: PDB:3CBY

    Description: The Dvl2 PDZ Domain in Complex with a Phage-Derived C-terminal Peptide (C1)

  4. The Dvl2 PDZ Domain in Complex with the N3 Inhibitory Peptide PDB

    ID: PDB:3CC0

    Description: Dishevelled-2

  5. The Dvl2 PDZ Domain in Complex with the N2 Inhibitory Peptide PDB

    ID: PDB:3CBZ

    Description: Dishevelled-2

  6. Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from monomeric fraction PDB

    ID: PDB:5LNP

    Description: Segment polarity protein dishevelled homolog DVL-2

    gene.name: DVL2
  7. Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits b-catenin degedation ArrayExpress

    ID: E-GEOD-41892

    Description: on altered the expression of LRP5, Naked 1 and 2, DVL2, DVL3, Axin 1 and GSKβ3 proteins, and also altered expression of several genes regulated by β-catenin. In conclusion, these results provide the first evidence for TSPAN12 playing a role in supporting primary tumor growth and suppressing metastasis. TSPAN12 appears to function by stabilizing FZD4-LRP5 association, in support of canonical Wnt-pathway signaling, leading to enhanced β-catenin expression and function. 4 samples = 2 Control + 2 TSPAN12KD...

  8. DCT1A_XENLA UniProt:Swiss-Prot

    ID: Q8JJ48

    Description: Dapper 1-A Interaction with tcf7l1-A PDZ-binding Abrogates binding to dvl2

  9. Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits β-catenin degradation BioProject

    ID: PRJNA178411

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: lation altered expression of LRP5, Naked 1 and 2, DVL2, DVL3, Axin 1 and GSKβ3 proteins. TSPAN12 ablation also altered expression of several genes regulated by β-catenin (e.g. CCNA1, CCNE2, WISP1, ID4, SFN, ME1) that may help to explain altered tumor growth and metastasis. In conclusion, these results provide the first evidence for TSPAN12 playing a role in supporting primary tumor growth and suppressing metastasis. TSPAN12 appears to function by stabilizing FZD4-LRP5 association, in support of canonical Wnt-pathway signaling, leading to enhanced β-catenin expression and function. Overall design: 4 samples = 2 Control + 2 TSPAN12KD...
  10. Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation ArrayExpress

    ID: E-GEOD-54611

    Description: ecules involved in the canonical pathway, such as DVL2, LEF1, CCND1 and c-Myc, and an up- regulation of DKK, a well-known negative regulator of canonical WNT signaling, in MLK3 mutant cells. Additionally, FZD6 and FZD10 genes, known to act as negative regulators of the canonical WNT signaling cascade and as positive regulators of the planar cell polarity (PCP) pathway, a non-canonic WNT pathway, were found to be up-regulated in P252H cells. 9 samples, 2 conditions with 3 biological replicates per condition...

  11. Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from dimeric fraction PDB

    ID: PDB:5SUY

    Description: Segment polarity protein dishevelled homolog DVL-2

    gene.name: DVL2
  12. Dishevelled PDZ domain homodimer PDB

    ID: PDB:3FY5

    Description: Segment polarity protein dishevelled homolog DVL-2

    gene.name: dsh, dvl2
  13. Crystal Structure of Monomeric Uncomplexed form of Xenopus dishevelled PDZ domain PDB

    ID: PDB:2F0A

    Description: Segment polarity protein dishevelled homolog DVL-2

    gene.name.raw: dvl2
  14. Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh) PDB

    ID: PDB:2REY

    Description: Segment polarity protein dishevelled homolog DVL-2

    gene.name: DVL2
  15. Domain-swapped dimer of human Dishevelled2 DEP domain: C-centered monoclinic crystal form crystallised from monomeric fraction PDB

    ID: PDB:5SUZ

    Description: Segment polarity protein dishevelled homolog DVL-2

    gene.name: DVL2
  16. Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits b-catenin degedation OmicsDI

    ID: E-GEOD-41892

    Date Released: 11-08-2012

    Description: on altered the expression of LRP5, Naked 1 and 2, DVL2, DVL3, Axin 1 and GSKβ3 proteins, and also altered expression of several genes regulated by β-catenin. In conclusion, these results provide the first evidence for TSPAN12 playing a role in supporting primary tumor growth and suppressing metastasis. TSPAN12 appears to function by stabilizing FZD4-LRP5 association, in support of canonical Wnt-pathway signaling, leading to enhanced β-catenin expression and function. 4 samples = 2 Control + 2 TSPAN12KD...

  17. Cell fate and adhesion dynamics rely on Ror2-mediated alternative Wnt signaling during tumor progression BioProject

    ID: PRJNA362571

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: e 1 (ROCK1) activity downstream of Dishevelled-2 (Dvl2) were implicated. Collectively, these studies illustrate the integration and collaboration of Wnt pathways in basal-like breast cancer, where Ror2 provides a spatiotemporal function to regulate the balance of Wnt signaling and cellular heterogeneity during tumor progression. Overall design: Total RNA from murine p53null mammary tumors was hybridized to agilent microarrays for gene expression analysis...
  18. Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation BioProject

    ID: PRJNA237219

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ecules involved in the canonical pathway, such as DVL2, LEF1, CCND1 and c-Myc, and an up- regulation of DKK, a well-known negative regulator of canonical WNT signaling, in MLK3 mutant cells. Additionally, FZD6 and FZD10 genes, known to act as negative regulators of the canonical WNT signaling cascade and as positive regulators of the planar cell polarity (PCP) pathway, a non-canonic WNT pathway, were found to be up-regulated in P252H cells. Overall design: 9 samples, 2 conditions with 3 biological replicates per condition...
  19. Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation OmicsDI

    ID: E-GEOD-54611

    Date Released: 06-03-2014

    Description: ecules involved in the canonical pathway, such as DVL2, LEF1, CCND1 and c-Myc, and an up- regulation of DKK, a well-known negative regulator of canonical WNT signaling, in MLK3 mutant cells. Additionally, FZD6 and FZD10 genes, known to act as negative regulators of the canonical WNT signaling cascade and as positive regulators of the planar cell polarity (PCP) pathway, a non-canonic WNT pathway, were found to be up-regulated in P252H cells. 9 samples, 2 conditions with 3 biological replicates per condition...


Displaying 19 of 19 results for "DVL2"