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Displaying 20 of 220 results for "DOT1L"
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  1. Effect of Dot1l deletion on LSKs and GMPs BioProject

    ID: PRJNA236783

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse Dot1l ko RNA-seq] BioProject

    ID: PRJNA308488

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Gene expression changes upon Dot1L knockdown and Dot1L inhibitor treatment during reprogramming BioProject

    ID: PRJNA139971

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse Mll1 ko RNA-seq] BioProject

    ID: PRJNA308489

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Global gene expression analysis of Dot1l-deficient and control intestinal villus cells in mouse BioProject

    ID: PRJNA178007

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Expression profiling of MDA-MB-231 breast cancer cells treated with DOT1L inhibitors and siDOT1L BioProject

    ID: PRJNA244410

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Expression Profiling of Mixed Lineage Leukemia Cells Treated with a Potent Small-Molecule DOT1L Inhibitor BioProject

    ID: PRJNA140999

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Functional interdependency of BRD4 and DOT1L in MLL leukaemia BioProject

    ID: PRJNA292064

    Access Type: download

  9. The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse Dot1l ko RNA-seq] ArrayExpress

    ID: E-GEOD-76748

    Description: hanges associated with homozygous inactivation of Dot1l or Mll1 in MN1 driven AML Methods: We sequenced mRNA from murine LSK-cells transformed using forced expression of MN1 (MSCV-MN1-IRES-GFP), and transduced with Cre-vect...

  10. Gene expression induced by DOT1L and Menin inhibition in cell line models of leukemia BioProject

    ID: PRJNA268658

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Effect of Dot1l deletion on LSKs and GMPs ArrayExpress

    ID: E-GEOD-54498

    Description: We wanted to investigate the effects of Dot1l deletion on gene expression in LSKs and GMPs of C57/BL6 mice Aberrant Hox gene activation is a recurrent feature in several d...

  12. Solution NMR structure of DOT1L in complex with AF9 (DOT1L-AF9) PDB

    ID: PDB:2MV7

    Description: Protein AF-9, Histone-lysine N-methyltransferase, H3 lysine-79 specific (E.C.2.1.1.43)

  13. Expression changes after loss of Dot1l in murine MLL-AF9 leukemia cells BioProject

    ID: PRJNA135857

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. Global gene expression analysis of Dot1l-deficient and control intestinal villus cells in mouse ArrayExpress

    ID: E-GEOD-41710

    Description: tion, which is catalyzed by the methyltransferase DOT1L. Human leukemias carrying MLL gene rearrangements show DOT1L-mediated H3K79 methylation and aberrant expression of leukemogenic genes. DOT1L inhibitors reverse these effects but their clinical use is potentially limited by toxicity in Wnt-dependent tissues such as intestinal epithelium. Genome-wide positioning of the H3K79me2 mark in ...

  15. Gene expression changes upon Dot1L knockdown and Dot1L inhibitor treatment during reprogramming ArrayExpress

    ID: E-GEOD-29253

    Description: that inhibition of the histone methyltransferase, Dot1L, accelerated somatic cell reprogramming, significantly increased the yield of induced pluripotent stem (iPS) cell colonies, and substituted for Klf4 and c-Myc in the reprogramm...

  16. Gene expression changes upon Dot1L knockdown and Dot1L inhibitor treatment during reprogramming OmicsDI

    ID: E-GEOD-29253

    Date Released: 05-02-2014

    Description: that inhibition of the histone methyltransferase, Dot1L, accelerated somatic cell reprogramming, significantly increased the yield of induced pluripotent stem (iPS) cell colonies, and substituted for Klf4 and c-Myc in the reprogramm...

  17. The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse Dot1l ko RNA-seq] OmicsDI

    ID: E-GEOD-76748

    Date Released: 01-16-2016

    Description: hanges associated with homozygous inactivation of Dot1l or Mll1 in MN1 driven AML Methods: We sequenced mRNA from murine LSK-cells transformed using forced expression of MN1 (MSCV-MN1-IRES-GFP), and transduced with Cre-vect...

  18. Effect of Dot1l deletion on LSKs and GMPs OmicsDI

    ID: E-GEOD-54498

    Date Released: 09-15-2014

    Description: We wanted to investigate the effects of Dot1l deletion on gene expression in LSKs and GMPs of C57/BL6 mice Aberrant Hox gene activation is a recurrent feature in several d...

  19. The Leukemia-associated Mllt10/Af10- Dot1l, dedicated b-catenin coactivators essential for intestinal homeostasis BioProject

    ID: PRJNA126101

    Keywords: Transcriptome or Gene expression

    Access Type: download

  20. complex of Dot1l with SS148 PDB

    ID: PDB:5JUW

    Description: Histone-lysine N-methyltransferase, H3 lysine-79 specific (E.C.2.1.1.43)


Displaying 20 of 220 results for "DOT1L"