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Displaying 20 of 40 results for "DNASE1L2"
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  1. ADDB_STAAM UniProt:Swiss-Prot

    ID: Q99VC4

    Description: ATP-dependent helicase/deoxyribonuclease subunit B UvrD-like helicase ATP-binding UvrD-like helicase C-terminal ATP ...

  2. ADDB_STAAN UniProt:Swiss-Prot

    ID: Q7A6H5

    Description: ATP-dependent helicase/deoxyribonuclease subunit B UvrD-like helicase ATP-binding UvrD-like helicase C-terminal ATP ...

  3. ADDB_BACP2 UniProt:Swiss-Prot

    ID: A8FBR0

    Description: ATP-dependent helicase/deoxyribonuclease subunit B UvrD-like helicase ATP-binding UvrD-like helicase C-terminal ATP ...

  4. type controls to study the influence of ubiquitin-like proteases in plant transcriptional modulation... ArrayExpress

    ID: E-GEOD-43883

    Description: tive is to determinate the influence of Ubiquitin-Like Proteases in plant transcriptional modulation. The experiment will also allow us to find what transcriptional cues are particularly affected in the mutants relatively to wild-typ...

  5. Structure of recombinant human DNase I (rhDNaseI) in complex with Magnesium and Phosphate. PDB

    ID: PDB:4AWN

    Description: DEOXYRIBONUCLEASE-1 (E.C.3.1.21.1)

  6. Virus purification methods for metagenomes : Evaluation of methods to purify virus-like particles for the sequencing of intestinal viromes BioProject

    ID: PRJEB6941

    Keywords: Other

    Access Type: download

  7. Transcription profiling of Enterococcus faecalis wild type, delta-relA and delta-relAsp (partial deletion) strains ArrayExpress

    ID: E-MEXP-2112

    Description: RNeasy Midi Kit (QIAGEN). RNAs were subjected to 2 DNase treatments, and prepared for chips hybridization....

  8. Alterations in Cell Growth and Signaling in ErbB3 Binding Protein -1 (Ebp1) Deficient Mice ArrayExpress

    ID: E-GEOD-13718

    Description: ent mice carrying a gene trap insertion in intron 2 of the Ebp1 (pa2g4) gene. Results: Ebp1 -/- mice were on average 30% smaller than wild type and heterozygous sex matched littermates. Growth retardation was apparent from Day 10 until Day 30. IGF-1 production and IGBP-3 and 4 protein levels were reduced in both embryo fibroblasts and adult knock-out mice. The proliferation of fibroblasts derived from Day 12.5 knock out embryos was also d...

  9. Rattus norvegicus strain:FAO : Comprehensive identification of insulin-dependently changed genes in rat hepatoma FAO cells BioProject

    ID: PRJDB4376

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ve previously shown that the additional secretion-like pulse stimulation induced a transient activation of S6K, and productions of fructose-1,6-bisphosphate and glycogen, and that the basal secretion-like ramp stimulation induced sustained suppressions of G6Pase and PEPCK at low-dose of insulin. Here we performed RNA sequencing to comprehensively identify insulin-dependently changed genes in rat hepatoma FAO cells, prior to analysis of the temporal patte...
  10. cDNA microarray analysis of gene expression in blood mononuclear cells of Yorkshire pigs with SLA-DRB1 defined genotypes BioProject

    ID: PRJNA100085

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: lly new allele). Total RNA was treated with Dnase I treated and amplified. The amplified RNA was reverse transcribed using random primers and incorporating 5-(3-aminoallyl)-dUTP for post-synthesis labelling of the cDNA with the appropriate fluor dyes. Hybridization was performed on a bovine immune-endocrine in-house cDNA microarray printed on glass slides. Microarray fold-change analysis revealed that animals carrying confirmed SLA alleles (SLA-DRB1*070701 and SLA-DRB1*050502) showed consistent differences in gene expression when compared to the two other groups. On the other hand, the group carrying a potentially new allele showed differences that varied depending on the group it was being compared to. Genes that were identified as differentially expressed include macrophage inflammatory protein 1, interleukin 1, toll-like receptor 2 and caspase 1. A bet...
  11. Transcription profiling by array of Drosophila testes mutant for bam, aly or sa ArrayExpress

    ID: E-GEOD-28728

    Description: instructions. The genomic DNA was degraded using 2 Units of DNase I (Fermentas, #EN0521, Glen Burnie, MD, USA) at 37 degreeC for 20 minutes. RNA integrity was checked by gel electrophoresis (1% agarose). Approximately 4 μg of total RNA from each biological replicate were used to generate labeling probes to hybridize with the Affymetix GeneChip Drosophila Genome 2.0 Array according to the Affymetrix protocol. Three biological replicates were performed for each genotype. Microarray hybridization was processed at the Core Facility at the Stanford University School of Medicine and the raw data were exported from the Affymetrix Microarray Suite (MAS). The CEL files were used for signal normalization with RMA as part of the limma package from the Bioconductor R packages ()....

  12. Proliferating Langerhans cells dampen inflammation in established mouse psoriatic lesions BioProject

    ID: PRJNA273651

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ve role. Topical application of Imiquimod, a Toll-like receptor 7 agonist, induces psoriasis in patients and psoriasiform inflammation in mice. We showed that daily application of Imiquimod for 14 days recapitulated both the initiation and the maintenance phase of psoriasis. Based on our ability to discriminate Langerhans cells (LCs), conventional DCs, monocytes, monocyte-derived DCs and macrophages in the skin, w...
  13. The genome-wide transcriptional response to light in Pseudomonas putida KT2440 BioProject

    ID: PRJNA347918

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: (cyclopropane synthase), folE (GTP cyclohydrolase I), cryB (cryptochrome-like protein), and multiple hypothetical genes. Transcriptional analysis based on a β-galactosidase reporter assay with single-, double-, and triple-knockout mutants of pplR1–pplR3 showed that deletion of pplR1–pplR3 completely abolished the light-inducible transcription in P. putida, which indicates that the transcription of light-inducible genes is under the ternary regulation of PplR proteins. DNase I footprint assay showed that PplR1 protein specifically binds to the pro...
  14. Protective monocytes in cerebral ischemia BioProject

    ID: PRJNA328868

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: d in brain by systemic administration of the Toll-like receptor-4 ligand lipopolysaccharide (LPS). Different populations of immune cell could potentially play a role in PC induced by LPS. In particular, monocytes, which are the main target of LPS, can exert a powerful protective effect either directly or by modulating the immune system. Overall design: C57Bl/6 male mice (8-12 weeks old) were treated with 0.5 mg/kg LPS i.p. (experimental) or saline (control). Twentyfour hours later mice were transcardially perfused with cold PBS and brains were harvested. Brains from 3-4 mice were pooled and enzymatically digested with Liberase DH (Roche Diagnostics) and 50 U/ml DNase I (Worthington Biochemical) at 37°C for 45 min in an orbital shaker at 160 rpm. Mono...
  15. TGFbeta- and IMR induced epithelial cell differentiation in a three-dimensional intestinal crypt-villus axis model BioProject

    ID: PRJNA96579

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: esign: Human intestinal epithelial T84 cells (CCL 2´48, ATCC Rockville, MD, USA) were cultured in three-dimensional type I collagen gel as previously described Halttunen et al 1996 . T84 cells were induced to differentiate either by adding 20 ng/ml human recombinant TGFbeta1 (hTGF-beta1, R&D Systems Europe, Oxon, UK) or by soluble factors secreted by IMR-90 type human embryonic lung fibroblasts (CCL 186, ATCC). IMR fibroblasts, cultured on the top of the epithelial cells, were separated from the epithelial cells by cell-free collagen layer. T84 cells cultured within collagen gel supplemented with medium were used as undifferentiated cont...
  16. Alterations in Cell Growth and Signaling in ErbB3 Binding Protein -1 (Ebp1) Deficient Mice BioProject

    ID: PRJNA110395

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ent mice carrying a gene trap insertion in intron 2 of the Ebp1 (pa2g4) gene. Results: Ebp1 -/- mice were on average 30% smaller than wild type and heterozygous sex matched littermates. Growth retardation was apparent from Day 10 until Day 30. IGF-1 production and IGBP-3 and 4 protein levels were reduced in both embryo fibroblasts and adult knock-out mice. The proliferation of fibroblasts derived from Day 12.5 knock out embryos was also d...
  17. Transcription profiling of mouse NR3B-null model to study NRB3 subunit role on motor neuron function ArrayExpress

    ID: E-GEOD-5035

    Description: n related to ablation of the NR3B gene. We would like to use the facility provided by the NINDS/NIMH Microarray Consortium to identify true outlier genes that show abnormal expression patterns in these mice. Analysis of these outlier genes will help to identify changes in networks and pathways that may cause the death of NR3B-null mice. These studies will further help to elucidate the functional role of NR3B in motor neurons. We will compare samples from the hindbrain and spinal cord of wild type and NR3B null mice to identify true outlier genes that show abnormal expression patterns, which may be implicated in the death of NR3B-null mice; We hypothesize that genes with their transc...

  18. zhang-affy-arabi-50806 GEMMA

    ID: 269

    Keywords: functional genomics

    Description: n related to ablation of the NR3B gene. We would like to use the facility provided by the NINDS/NIMH Microarray Consortium to identify true outlier genes that show abnormal expression patterns in these mice. Analysis of these outlier genes will help to identify changes in networks and pathways that may cause the death of NR3B-null mice. These studies will further help to elucidate the functional role of NR3B in motor neurons. We will compare samples from the hindbrain and spinal cord of wild type and NR3B null mice to identify true outlier genes that show abnormal expression patterns, which may be implicated in the death of NR3B-null mice We hypothesize that genes with their transcr...

  19. Lithium promotes longevity through GSK3/NRF2-dependent hormesis ArrayExpress

    ID: E-MTAB-3809

    Description: the transcription factor nuclear factor erythroid 2-related factor (NRF-2). Combining genetic loss of the NRF-2 repressor Kelch-like ECH-associated protein 1 (Keap1) with lithium treatment revealed that high levels of NRF-2 activation conferred stress resistance, while low levels additionally promoted longevity. The discovery of GSK-3 as a new therapeutic target for aging will likely lead to more effective treatments that can modulate mammalian aging and further improve health in later life. The microarray experiment examines the transcriptional profiles of wild-type (w1118...

  20. Mechanisms and disease associations of haplotype-dependent allele specific DNA methylation: Methyl-seq data for the identification of hap-ASM BioProject

    ID: PRJNA315118

    Keywords: Epigenomics

    Access Type: download

    dataset.description: pG islands, CpG island shores, shelves, and DNAse I hypersensitive sites. DNA was sheared to an average size of 250 bp and bisulfite converted with the EZ DNA methylation kit (Zymo). Paired-end reads (150 bp) were generated with an Illumina HiSeq2000 sequencer. One of the brain samples (5984) was relatively under-represented in the library, so additional sequences were generated on a MiSeq sequencer to improve the coverage for this sample. After trimming for low-quality bases (Phred score<30) and reads with a length <40 bp with TrimGalore, the reads were aligned to the human genome (GRCh37) using Bismark and duplicate reads were removed using Samtools. Methylation calling was performed using Bismark and and SNP calling was performed with BisSNP with default settings and dbSNP137 as references. ASM calling was performed with Bismark, after separating the valid SNP-containing reads by allele....

Displaying 20 of 40 results for "DNASE1L2"