DMC1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 49 results for "DMC1"
i
  1. ssDNA mapping in dmc1 strains BioProject

    ID: PRJNA155157

    Keywords: Variation

    Access Type: download

  2. ssDNA mapping in dmc1 strains ArrayExpress

    ID: E-GEOD-30071

    Description: hment was used to map and compare DSB hotspots in dmc1, pch2 dmc1, sir2 dmc1, orc1-161 dmc1, dmc1 rdnadelete and

  3. ssDNA mapping in dmc1 strains OmicsDI

    ID: E-GEOD-30071

    Date Released: 05-02-2014

    Description: hment was used to map and compare DSB hotspots in dmc1, pch2 dmc1, sir2 dmc1, orc1-161 dmc1, dmc1 rdnadelete and

  4. Humanized PRDM9 Mouse Testis H3K4me3 and DMC1 ChIP-seq BioProject

    ID: PRJNA298164

    Keywords: Other

    Access Type: download

  5. Filament of octameric rings of DMC1 recombinase from Homo sapiens PDB

    ID: PDB:4HYY

    Description: Meiotic recombination protein DMC1/LIM15 homolog

  6. Crystal structure of the human Dmc1 protein PDB

    ID: PDB:1V5W

    Description: Meiotic recombination protein DMC1/LIM15 homolog

  7. Crystal structure of the human Dmc1-M200V polymorphic variant PDB

    ID: PDB:2ZJB

    Description: Meiotic recombination protein DMC1/LIM15 homolog

  8. Homo sapiens : The DMC1-ssDNA complex preferentially targets to the nucleosome-free DNA region in human chromosomes BioProject

    ID: PRJDB2814

    Keywords: Other

    Access Type: download

  9. Data from: Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks Dryad

    DateIssued: 01-28-2014

    Description: t to the conserved, meiosis-specific recombinase, Dmc1, which preferentially repairs programmed DSBs using homologs. Despite the different preferences for repair templates, both Rad51 and Dmc1 are required for interhomolog recombination during meiosis. This paradox has recently been explained by the finding that Rad51 protein, but not its strand exchange activity, promotes Dmc1 function in budding yeast. Rad51 activity is inhibited in dmc1Δ mutants, where the failure to re...

  10. Meiotic DNA double strand breaks in the yeast Saccaromyces cerevisiae OmicsDI

    ID: E-GEOD-8981

    Date Released: 05-02-2014

    Description: in rad50S mutants, analysis of meiotic ssDNA from dmc1? shows that most of these regions have significant DSB activity. Thus, DSBs are distributed much more uniformly than was previously believed. Southern-blot assays of DSBs in selected regions in dmc1?, rad50S and wild-type cells confirm these findings. Comparisons of DSB signals in dmc1, dmc1 rad51, and dmc1 spo11 mutant strains identify Dmc1 as the primary strand transfer activity genome-wide, and Spo11-induced lesions as initiating all meiotic recombination. Keywords: DSB mapping, ChIP-chip, single strand DNA , BND cellulose We use two different strategies to map the genome-wide distribution of meiotic DSBs in the yeast Saccharomyces cerevisiae. The first is a chromatin immunoprecipitation (ChIP) based approach that targets the Spo11p protein, which remains covalently attached to DSB ends in the rad50S mutant background. The second approach involves BND cellulose enrichment of the single strand DNA (ssDNA) recombination intermediate formed by end-r...

  11. During Meiosis in Yeast Prevents Competition with Dmc1 for Repair of Double-Strand Breaks... BioProject

    ID: PRJNA217886

    Keywords: genome sequencing

    Access Type: download

  12. DMC1_LILLO UniProt:Swiss-Prot

    ID: P37384

    Description: Meiotic recombination protein DMC1 homolog ATP ssDNA or dsDNA ssDNA ssDNA or dsDNA ssDNA or dsDNA ssDNA

  13. Meiotic DNA double strand breaks in the yeast Saccaromyces cerevisiae ArrayExpress

    ID: E-GEOD-8981

    Description: in rad50S mutants, analysis of meiotic ssDNA from dmc1? shows that most of these regions have significant DSB activity. Thus, DSBs are distributed much more uniformly than was previously believed. Southern-blot assays of DSBs in selected regions in dmc1?, rad50S and wild-type cells confirm these findings. Comparisons of DSB signals in dmc1, dmc1 rad51, and dmc1 spo11 mutant strains identify Dmc1 as the primary strand transfer activity genome-wide, and Spo11-induced lesions as initiating all meiotic recombination. Keywords: DSB mapping, ChIP-chip, single strand DNA , BND cellulose We use two different strategies to map the genome-wide distribution of meiotic DSBs in the yeast Saccharomyces cerevisiae. The first is a chromatin immunoprecipitation (ChIP) based approach that targets the Spo11p protein, which remains covalently attached to DSB ends in the rad50S mutant background. The second approach involves BND cellulose enrichment of the single strand DNA (ssDNA) recombination intermediate formed by end-r...

  14. DMC1_MOUSE UniProt:Swiss-Prot

    ID: Q61880

    Description: Meiotic recombination protein DMC1/LIM15 homolog ATP ssDNA or dsDNA ssDNA ssDNA or dsDNA ssDNA or dsDNA ssDNA

  15. DMC1_SOYBN UniProt:Swiss-Prot

    ID: Q96449

    Description: Meiotic recombination protein DMC1 homolog ATP ssDNA or dsDNA ssDNA ssDNA or dsDNA ssDNA or dsDNA ssDNA

  16. Genome wide maps of Dmc1 in testis of Hop2 null mice. BioProject

    ID: PRJNA132675

    Keywords: Epigenomics

    Access Type: download

  17. Meiotic DNA double strand breaks in the yeast Saccaromyces cerevisiae BioProject

    ID: PRJNA102441

    Keywords: Epigenomics

    Access Type: download

    dataset.description: in rad50S mutants, analysis of meiotic ssDNA from dmc1? shows that most of these regions have significant DSB activity. Thus, DSBs are distributed much more uniformly than was previously believed. Southern-blot assays of DSBs in selected regions in dmc1?, rad50S and wild-type cells confirm these findings. Comparisons of DSB signals in dmc1, dmc1 rad51, and dmc1 spo11 mutant strains identify Dmc1 as the primary strand transfer activity genome-wide, and Spo11-induced lesions as initiating all meiotic recombination. Keywords: DSB mapping, ChIP-chip, single strand DNA , BND cellulose Overall design: We use two different strategies to map the genome-wide distribution of meiotic DSBs in the yeast Saccharomyces cerevisiae. The first is a chromatin immunoprecipitation (ChIP) based approach that targets the Spo11p protein, which remains covalently attached to DSB ends in the rad50S mutant background. The second approach involves BND cellulose enrichment of the single strand DNA (ssDNA) recombination intermediate...
  18. PGENETICS_D_13_01530R2_ReCombine_data Dryad

    DateIssued: 01-28-2014

    dataset.keywords: Dmc1
  19. Saccharomyces cerevisiae S96 X YJM789 : Saccharomyces cerevisiae S96 X YJM789 Genome sequencing BioProject

    ID: PRJNA217883

    Keywords: Genome sequencing

    Access Type: download

    dataset.description: Down-regulation of Rad51 Activity During Meiosis in Yeast Prevents Competition with Dmc1 for Repair of Double-Strand Breaks
  20. Meiotic DNA double strand breaks in wild-type and set1∆ cells ArrayExpress

    ID: E-GEOD-12879

    Description: iled the DSB sites by immunoprecipitating Rfa1 in dmc1∆ cells, at 5h for the wild-type experiment and at 7h for the set1∆ cells....


Displaying 20 of 49 results for "DMC1"