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Displaying 16 of 16 results for "DKC1"
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  1. Study the transcriptional level changes of induced pluripotent stem (iPS) cells from X-linked Dyskeratosis Congenita (DC) Patients BioProject

    ID: PRJNA278084

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Next generation sequencing identifies polyadenylated species of hTR BioProject

    ID: PRJNA299280

    Keywords: Other

    Access Type: download

    dataset.description: ated to Flag-tagged versions of PABPN1, hTERT and Dyskerin. In total, we obtained 2,716,342, 3,152,013, and 3,077,395 hTR-specific reads for the PABPN1, hTERT, and Dyskerin purifications, respectively. We found that the majority of polyadenylated telomerase RNA recovered in the PABPN1, hTERT, and Dyskerin
  3. Comparison of ribosomes between control and dyskerin-depleted human cells OmicsDI

    ID: PXD001274

    Date Released: 05-07-2015

    Description: Dyskerin is a pseudouridine synthase involved in fundamental cellular processes (including rRNA and snRNA modification and telomer...

  4. Transcriptome-wide mapping reveals widespread dynamic regulated pseudouridylation of mRNA BioProject

    ID: PRJNA257386

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: to mammals, but are reduced in cells derived from dyskeratosis congenita patients, where the pseudouridine synthase DKC1 is mutated, compared to age matched controls. Our results establish pseudouridine as a ubiquitous and dynamic modification in mRNA, and provide a sensitive, quantitative and transcriptome-wide methodology to address its underlying mechanisms and function. Overall design: Examination of m6A methylation in human Hek293 and A549 cell lines, in human embryonic stem cells (ESCs) undergoing differentiation to neural progenitor cells (NPCs), in OKMS inducible fibroblasts reprogrammed into iPSC, and upon knockdown of factors using siRNAs or shRNAs....
  5. Transcriptome-wide mapping reveals widespread dynamic regulated pseudouridylation of mRNA ArrayExpress

    ID: E-GEOD-60047

    Description: to mammals, but are reduced in cells derived from dyskeratosis congenita patients, where the pseudouridine synthase DKC1 is mutated, compared to age matched controls. Our results establish pseudouridine as a ubiquitous and dynamic modification in mRNA, and provide a sensitive, quantitative and transcriptome-wide methodology to address its underlying mechanisms and function. Examination of m6A methylation in human Hek293 and A549 cell lines, in human embryonic stem cells (ESCs) undergoing differentiation to neural progenitor cells (NPCs), in OKMS inducible fibroblasts reprogrammed into iPSC, and upon knockdown of factors using siRNAs or shRNAs....

  6. Solution structure of the dyskeratosis congenita mutant P2b hairpin from human telomerase RNA PDB

    ID: PDB:1Q75

    Description: DKC mutant P2b telomerase RNA

  7. Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing BioProject

    ID: PRJNA186963

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: oRNP core proteins NOP56, NOP58, Fibrillarin, and Dyskerin in HEK293 cells. Small RNA profiling using RNA-seq in HEK293 and HeLa cells, small RNA profiling using IP-seq of Ago2 associated small RNAs....
  8. Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing ArrayExpress

    ID: E-GEOD-43666

    Description: oRNP core proteins NOP56, NOP58, Fibrillarin, and Dyskerin in HEK293 cells. Small RNA profiling using RNA-seq in HEK293 and HeLa cells, small RNA profiling using IP-seq of Ago2 associated small RNAs....

  9. Transcriptome-wide mapping reveals widespread dynamic regulated pseudouridylation of mRNA OmicsDI

    ID: E-GEOD-60047

    Date Released: 09-12-2014

    Description: to mammals, but are reduced in cells derived from dyskeratosis congenita patients, where the pseudouridine synthase DKC1 is mutated, compared to age matched controls. Our results establish pseudouridine as a ubiquitous and dynamic modification in mRNA, and provide a sensitive, quantitative and transcriptome-wide methodology to address its underlying mechanisms and function. Examination of m6A methylation in human Hek293 and A549 cell lines, in human embryonic stem cells (ESCs) undergoing differentiation to neural progenitor cells (NPCs), in OKMS inducible fibroblasts reprogrammed into iPSC, and upon knockdown of factors using siRNAs or shRNAs....

  10. Expression data from Zea mays cultivars Tietar and DKC 6575 ArrayExpress

    ID: E-GEOD-59533

    Description: Maize transgenic event MON810, grown and commercialised worldwide, is the only cultivated GM event in EU. Maize MON810, variety DKC6575, and the corre...

    datasetDistributions.accessURL: https://www.ebi.ac.uk/arrayexpress/files/E-GEOD-59533/E-GEOD-59533.raw.1.zip
  11. DNA Methylation in PRDM8 is a Biomarker for Dyskeratosis Congenita BioProject

    ID: PRJNA303165

    Keywords: Epigenomics

    Access Type: download

  12. Comparison of ribosomes between control and dyskerin-depleted human cells ProteomeXchange

    ID: PXD001274

    Instrument: LTQ Orbitrap Velos

    Date Released: 05-07-2015

  13. Solution structure of the P22S mutant of N-terminal CS domain of human Shq1 PDB

    ID: PDB:2MNW

    Description: Protein SHQ1 homolog

    dataset.keywords: Dyskerin
  14. Crystal structure of the P22S mutant of N-terminal CS domain of human Shq1 PDB

    ID: PDB:4PCK

    Description: P22S mutant of CS domain of human Shq1

    dataset.keywords.raw: dyskerin
  15. Crystal structure of the N-terminal CS domain of human Shq1 PDB

    ID: PDB:4PBD

    Description: CS domain of human Shq1

    dataset.keywords.raw: dyskerin
  16. Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing OmicsDI

    ID: E-GEOD-43666

    Date Released: 06-06-2013

    Description: oRNP core proteins NOP56, NOP58, Fibrillarin, and Dyskerin in HEK293 cells. Small RNA profiling using RNA-seq in HEK293 and HeLa cells, small RNA profiling using IP-seq of Ago2 associated small RNAs....


Displaying 16 of 16 results for "DKC1"