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Displaying 12 of 12 results for "DIO1"
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  1. IOD1_FELCA UniProt:Swiss-Prot

    ID: Q6V915

    Description: Type I iodothyronine deiodinase Helical Selenocysteine

  2. IOD1_ORENI UniProt:Swiss-Prot

    ID: O42449

    Description: Type I iodothyronine deiodinase Helical Selenocysteine

  3. IOD1_FUNHE UniProt:Swiss-Prot

    ID: Q804E1

    Description: Type I iodothyronine deiodinase Helical Selenocysteine

  4. IOD1_RABIT UniProt:Swiss-Prot

    ID: A4GT88

    Description: Type I iodothyronine deiodinase Helical Selenocysteine

  5. IOD1_CHICK UniProt:Swiss-Prot

    ID: O42411

    Description: Type I iodothyronine deiodinase Helical Selenocysteine

  6. IOD1_PIG UniProt:Swiss-Prot

    ID: Q6QN13

    Description: Type I iodothyronine deiodinase Helical Selenocysteine

  7. IOD1_XENLA UniProt:Swiss-Prot

    ID: Q2QEI3

    Description: Type I iodothyronine deiodinase Helical Selenocysteine

  8. IOD1_RAT UniProt:Swiss-Prot

    ID: P24389

    Description: Type I iodothyronine deiodinase Helical Selenocysteine Loss of enzyme acti...

  9. IOD1_SUNMU UniProt:Swiss-Prot

    ID: Q95N00

    Description: Type I iodothyronine deiodinase Helical Selenocysteine

  10. IOD1_CANLF UniProt:Swiss-Prot

    ID: P49894

    Description: Type I iodothyronine deiodinase Helical Selenocysteine

  11. Genome-wide association and epistatic studies in sporadic medullary and juvenile papillary thyroid carcinomas BioProject

    ID: PRJNA278802

    Keywords: Variation

    Access Type: download

    dataset.description: RNU1-55P) and three in juvenile PTC (RP11-648k4.2-DIO1, RP11-648k4.2-DMGDH and RP11-648k4.2-LOXL1). Interestingly, each interacting gene pair included a non-coding RNA, providing thus support to the relevance that these elements are increasingly gaining to explain cancer development and progression. Overall, this study contributes to the understanding of the genetic basis of thyroid cancer susceptibility in two different case scenarios such as sMTC and juvenile PTC. It opens further ways of knowledge of new heritable components of genetic risk to disease through association and statistical viewpoints. Overall design: DNA derived from peripheral blood was hybridized to Affymetrix Genome-Wide Human SNP 6.0 arrays. Two different series of patients were recruited, one with 66 sporadic medullary thyroid cancer (sMTC) patients, with no family history suggestive of MEN 2. The second group compiled 30 ju...
  12. Methyome profiling in serrated carcinoma BioProject

    ID: PRJNA281639

    Keywords: Epigenomics

    Access Type: download

    dataset.description: fferential methylation of 15 genes, including the iodothyronine deiodinase DIO3 and the forkhead family transcription factor FOXD2 genes which were validated at the CpG, mRNA and protein level. A quantification study of the methylation status of CpG sequences in FOXD2 demonstrated a novel region controlling gene expression. Moreover, differences in these markers were also evident when comparing SAC with CRC showing molecular and histological features of high level microsatellite instability. This methylome study demonstrates that SAC has a distinct epigenetic regulation pattern resulting in different biological functions and that DIO3 and FOXD2 might be molecular targets for a specific histology-oriented treatment of CRC. Overall design: HumanMethylation450K BeadChip (Illumina, Inc, San Diego, CA), using Infinium HD Methylation assay for genome-wide DNA methylation screening, was employed. In brief, genomic DNA (1000 ng) from each sample was bisulfite converted with the EZ DNA Methylation Kit (Zymo Research, Orange, CA) according to the manufacturer┬┤s recommendations. Bisulfite-treated DNA was isothermally amplified at 37┬░C (20-24h) and the DNA product was fragmented b...

Displaying 12 of 12 results for "DIO1"