DHRS7B | bioCADDIE Data Discovery Index
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Displaying 20 of 34 results for "DHRS7B"
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  1. DRS7B_XENLA UniProt:Swiss-Prot

    ID: Q0IH28

    Description: Dehydrogenase/reductase SDR family member 7B

  2. DRS7B_XENTR UniProt:Swiss-Prot

    ID: Q0VFE7

    Description: Dehydrogenase/reductase SDR family member 7B

  3. DRS7B_BOVIN UniProt:Swiss-Prot

    ID: Q3T0R4

    Description: Dehydrogenase/reductase SDR family member 7B

  4. DRS7B_DANRE UniProt:Swiss-Prot

    ID: Q566S6

    Description: Dehydrogenase/reductase SDR family member 7B

  5. GWAS of Familial Lung Cancer dbGaP

    ID: phs000629.v1.p1

    Description: ial cases for this study came from three sources: 1) one case each from families (at least 3 affected lung cancer cases in the family) included in the linkage analysis; 2) one case from linkage-eligible families (at least 3 affected lung cancer cases in the family) but where there were insufficient biospecimens available to make them informative for linkage analysis; and 3) one case from families not eligible for the linkage study with a

    Study Types: Case-Control

  6. Genome-Wide Association Study of Leprosy dbGaP

    ID: phs000217.v1.p1

    Description: d the follow-up study was performed by genotyping 93 SNPs in three independent samples consisting of 3254 cases and 5955 controls. We identified significant association (P<10-10) within six genes CCDC122 (13q14), C13orf31 (13q14), NOD2 (16q12), TNFSF15 (9q32), HLA-DR (6p21) and RIPK2 (8q21), and suggestive association (P=5.68x10-6) within LRRK2 (12q12). We also revealed suggestive evidence for C13orf31, LRRK2, NOD2 and RIPK2 to show stronger association in the multibacillary form than the paucibacillary form of leprosy. Our findings highlight the importance of the innate immune response, particularly NOD2-mediated signaling, in leprosy and suggests a new therapeutic target for leprosy. Here, the summary statistics from the initial genome-wide association analysis were reported....

    Study Types: Case-Control

  7. DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes dbGaP

    ID: phs000086.v2.p1

    Description: betes Control and Complications Trial (DCCT, 1982-93) and the Epidemiology of Diabetes Interventions and Complications follow-up study (EDIC, 1994-2016) have been ongoing for more tha...

  8. DCCT-EDIC Clinical Trial and Follow-up of Persons with Type 1 Diabetes dbGaP

    ID: phs000086.v3.p1

    Description: betes Control and Complications Trial (DCCT, 1982-93) and the Epidemiology of Diabetes Interventions and Complications follow-up study (EDIC, 1994-2016) have been ongoing for more than twe...

  9. SLCO1B1 Variants and Methotrexate Clearance dbGaP

    ID: phs000426.v1.p1

    Description: ALL who received methotrexate and identified 93 single nucleotide polymorphisms (SNPs). We found several common and rare non-synonymous (NS) SNPs associated with methotrexate clearance. NS SNPs predicted to be functionally damaging (common or rare) were more likely to be found among patients with the lowest adjusted methotrexate clearance (lowest 10%) than patients with high clearance (highest 10%). Four SLCO1B1 haplotypes were associated with reduced methotrexate clearance and we verified that these haplotypes have lower function with in vitro transport assays. We were able to quantitatively account for a third of the population variability in clearance of methotrexate with clinical and genetic covariates. This data set includes the dependent variable of methotrexate clearance and all of the SNP data available from arrays, sequencing, and genotyping....

    Study Types: Cohort

  10. Genome-Wide Association Analysis of Biomarkers in the InCHIANTI and BLSA dbGaP

    ID: phs000215.v2.p1

    Description: Version 1 The aim of this study was to identify gene(s) associated with serum iron concentrations. This dataset contains the results from a...

  11. Expression QTL (eQTL) Analysis in Human Primary Cells dbGaP

    ID: phs000225.v1.p1

    Description: The common genetic variants associated with complex traits typically lie in non-coding DNA and may alter gene regulation in a cell type-specific man...

    access.landingpage: http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000225.v1.p1
  12. PAGE: CALiCo: Atherosclerosis Risk in Communities (ARIC) dbGaP

    ID: phs000223.v1.p1

    Description: CALiCo ARIC The Atherosclerosis Risk in Communities Study (ARIC), sponsored by the National Heart, Lung and Blood Institute (NHLBI), is a prospective ...

    Study Types: Longitudinal

    studyGroup.Identifier: 1
  13. NIDDK IBDGC Crohn's Disease Genome-Wide Association Study dbGaP

    ID: phs000130.v1.p1

    Description: birth. Subjects were drawn from two cohorts: (1) persons with non-Jewish, European ancestry (561 cases and 563 controls), and (2) persons with Jewish ancestry (407 cases and 432 controls). Genotyping was performed at the Feinstein Institute for Medical Research. Seven-hundred fifty-four of the samples (468 cases and 286 controls) were taken from the NIDDK IBD Genetics Consortium cell line repository. These samples are identified in the IBD_Sample file. The subject IDs for these individuals may be used to r...

    Study Types: Case-Control

  14. Genome-wide Analysis of Lymphoma dbGaP

    ID: phs000328.v2.p1

    Description: Version 1. Diffuse Large B-cell Lymphoma (DLBCL) represents the most common form of B-cell non-Hodgkin Lymphoma (B-NHL), accounting for ~30...

  15. Genome-Wide Association Study of Leprosy and Dapsone Hypersensitivity Syndrome (DHS) dbGaP

    ID: phs000217.v2.p1

    Description: d the follow-up study was performed by genotyping 93 SNPs in three independent samples consisting of 3254 cases and 5955 controls. We identified significant association (P<10-10) within six genes CCDC122 (13q14), C13orf31 (13q14), NOD2(16q12), TNFSF15 (9q32), HLA-DR (6p21) and RIPK2 (8q21), and suggestive association (P=5.68x10-6) within LRRK2 (12q12). We also revealed suggestive evidence for C13orf31, LRRK2, NOD2 and RIPK2 to show stronger association in the multibacillary form than the paucibacillary form of leprosy. Our findings highlight the importance of the innate immune response, particularly NOD2-mediated signaling, in leprosy and suggests a new therapeutic target for leprosy. DHS GWAS Dapsone (DDS), as both an antibiotic and an anti-inflammatory agent, has been widely used for preventing and treating ...

    Study Types: Case-Control

  16. Whole-Genome Sequencing of Acute Myeloid Leukemia dbGaP

    ID: phs000159.v6.p4

    Description: We used massively parallel sequencing technology to sequence the genomic DNA of tumor cells (leukemic bone marrow) and normal cells (skin biopsy) obta...

    studyGroup.Identifier: 1
  17. Oncoarray Consortium - Lung Cancer Studies dbGaP

    ID: phs001273.v1.p1

    Description: ollution and passive smoking), diet, personal and family history of cancer, and occupational history from each participant. Peripheral blood samples (or mouthwash samples when they refused to donate blood) were collected from all participants. Coding of histology was based on 2001 WHO/IASLC. Genomic DNA was extracted based on standard protocol. The Canadian screening study. It includes the nested case-control samples from 3 screening programs: IELCAP-Toronto: Ever smokers of more than 10 pack-years age 50 and above were eligible for the I-ELCAP screening program since 2003, and a total of 4782 individuals have been enrolled in the Greater Toronto Area. Participants were administered a LDCT scan along with a standard study questionnaire at baseline. Blood samples were systematically collected at baseline since 2006. Participants who had an abnormality in a CT scan were followed up every 1 to 2 years. The screening program was organized by the Princess Margaret Hospital. PanCan: Ever smokers between the ages of 50-75 with no previous history of invasive cancer are eligible to participate in the study. The study was carried out across Canada in Vancouver, Calgary, Hamilton, Toronto, Ottawa, Quebec, Halifax, and St. John's. A total of 2537 smokers have been screened from 2008 to 2011. All study participants completed a detailed questionnaire, spirometry, collection of blood specimens for biomarker measurement and LDCT at baseline. All participants are followed for a minimum of 3 years. On yearly follow up, an updated shorter questionnaire is administered, blood is collected and CT scans are performed. Blood samples are available from all 2537 individuals. BCCA Screening Program: From 1990 to 2007, 4274 smokers above 40 years old who had smoked 20 pack-years or more were enrolled at BCCA. Upon enrollment, subjects completed a questionnaire for their lifestyle and medical history. Baseline spirometry was conducted using a flow-sensitive spirometer in accordance with the American Thoracic Society recommendations. Since 2000, a LDCT was obtained in 2440 individuals. The participants were followed prospectively to determine whether they developed lung cancer. A total of 9759 individuals participated in the CT screening program in Canada from these 3 programs. The samples included in this project is based on a subset of n...

    Study Types: Case-Control

  18. Whole-Genome Sequencing of Acute Myeloid Leukemia dbGaP

    ID: phs000159.v5.p3

    Description: We used massively parallel sequencing technology to sequence the genomic DNA of tumor cells (leukemic bone marrow) and normal cells (skin biopsy) obta...

    studyGroup.Identifier: 1
  19. Whole-Genome Sequencing of Acute Myeloid Leukemia dbGaP

    ID: phs000159.v7.p4

    Description: We used massively parallel sequencing technology to sequence the genomic DNA of tumor cells (leukemic bone marrow) and normal cells (skin biopsy) obta...

    studyGroup.Identifier: 1
  20. Whole-Genome Sequencing of Acute Myeloid Leukemia dbGaP

    ID: phs000159.v8.p4

    Description: We used massively parallel sequencing technology to sequence the genomic DNA of tumor cells (leukemic bone marrow) and normal cells (skin biopsy) obta...

    studyGroup.Identifier: 1

Displaying 20 of 34 results for "DHRS7B"