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Displaying 20 of 23 results for "CUL7"
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  1. Solution structure of the CUL7-CPH domain from Homo Sapiens; Northeast Structural Genomics Consortium target HT1. PDB

    ID: PDB:2JNG

    Description: Cullin-7

  2. CUL7_RAT UniProt:Swiss-Prot

    ID: D3ZEF4

    Description: Cullin-7 DOC Glu-rich Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in NEDD8)

  3. CUL7_PONAB UniProt:Swiss-Prot

    ID: Q5RCJ3

    Description: Cullin-7 DOC Phosphoserine Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in NEDD8)

  4. IRS1_HUMAN UniProt:Swiss-Prot

    ID: P35568

    Description: YXXM motif 4 YXXM motif 5 YXXM motif 6 YXXM motif 7 YXXM motif 8 YXXM motif 9 Poly-Gly Ser-rich Poly-Ser Poly-Ser Poly-Gln Pro-rich Phosphoserine Phosphoserine; by CK2 Phosphoserine; by RPS6KB1 Phosphoserine; by RPS6KB1 Phosphoserine; by IKKB, MAPK8 and RPS6KB1 Phosphoserine Phosphoserine Phosphoserine Phosp...

  5. LT_SV40 UniProt:Swiss-Prot

    ID: P03070

    Description: se T-ag OBD T-ag D1-type ATP Binding of LT to the CUL7 complex Binding to host TP53 protein ATPase activity C-terminal region CPD LXCXE motif Nuclear localization signal Poly-Asp N-acetylmethionine; by host Ph...

  6. Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis ArrayExpress

    ID: E-GEOD-60185

    Description: st tissue, involving almost 7000 genes (including CUL7 and ICAM2). Changes between DCIS and IBC involved around 1000 genes. In tumors, DNA methylation was associated with gene expression of almost 3000 genes (p<0.05, Bonferroni corrected) including both negative and positive correlations. A prognostic signature based on methylation level of 18 CpGs (representing genes such as IRF6, TBX5, ZNF259, KCTD21, EPN3, MACF1 and CSNK1G2) was associated to survival of breast cancer patients with invasive tumors, as well as to survival of patients with DCIS and mixed lesions of DCIS and IBC. This work demonstrates that changes in the epigenome occurs early in the neoplastic progression, provide evidence for the possible utilization of DNA methylation based markers of progression in the clinic, and highlights the importance of epigenetic changes in carcinogenesis. Bisulphite converted DNA from the 285 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip...

  7. CAND1_CAEEL UniProt:Swiss-Prot

    ID: G5ED41

    Description: Cullin-associated NEDD8-dissociated protein 1 HEAT 1 HEAT 2 HEAT 3 HEAT 4 HEAT 5 HEAT 6 HEAT 7 HEAT 8 HEAT 9 Asp...

  8. M4K1_HUMAN UniProt:Swiss-Prot

    ID: Q92918

    Description: 825. Retains kinase activity. Not degraded by the Cul7-RING ubiquitin-protein ligase complex containing FBXW8...

  9. CAND1_SCHPO UniProt:Swiss-Prot

    ID: Q9P3A8

    Description: Cullin-associated NEDD8-dissociated protein 1 HEAT 1 HEAT 2 HEAT 3 HEAT 4 HEAT 5 HEAT 6 HEAT 7 HEAT 8 HEAT 9 HEA...

  10. CAND1_CANAL UniProt:Swiss-Prot

    ID: Q5ADW3

    Description: Cullin-associated NEDD8-dissociated protein 1 HEAT 1 HEAT 2 HEAT 3 HEAT 4 HEAT 5 HEAT 6 HEAT 7 HEAT 8

  11. CAND1_BOVIN UniProt:Swiss-Prot

    ID: A7MBJ5

    Description: Removed Cullin-associated NEDD8-dissociated protein 1 HEAT 1 HEAT 2 HEAT 3 HEAT 4 HEAT 5 HEAT 6 HEAT 7 HEAT 8 HEAT 9 HEA...

  12. CAND1_PONAB UniProt:Swiss-Prot

    ID: Q5R6L5

    Description: Removed Cullin-associated NEDD8-dissociated protein 1 HEAT 1 HEAT 2 HEAT 3 HEAT 4 HEAT 5 HEAT 6 HEAT 7 HEAT 8 HEAT 9 HEA...

  13. CAND1_RAT UniProt:Swiss-Prot

    ID: P97536

    Description: Removed Cullin-associated NEDD8-dissociated protein 1 HEAT 1 HEAT 2 HEAT 3 HEAT 4 HEAT 5 HEAT 6 HEAT 7 HEAT 8 HEAT 9 HEA...

  14. Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis BioProject

    ID: PRJNA257696

    Keywords: Epigenomics

    Access Type: download

    dataset.description: st tissue, involving almost 7000 genes (including CUL7 and ICAM2). Changes between DCIS and IBC involved around 1000 genes. In tumors, DNA methylation was associated with gene expression of almost 3000 genes (p<0.05, Bonferroni corrected) including both negative and positive correlations. A prognostic signature based on methylation level of 18 CpGs (representing genes such as IRF6, TBX5, ZNF259, KCTD21, EPN3, MACF1 and CSNK1G2) was associated to survival of breast cancer patients with invasive tumors, as well as to survival of patients with DCIS and mixed lesions of DCIS and IBC. This work demonstrates that changes in the epigenome occurs early in the neoplastic progression, provide evidence for the possible utilization of DNA methylation based markers of progression in the clinic, and highlights the importance of epigenetic changes in carcinogenesis. Overall design: Bisulphite converted DNA from the 285 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip...
  15. Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis OmicsDI

    ID: E-GEOD-60185

    Date Released: 08-16-2014

    Description: st tissue, involving almost 7000 genes (including CUL7 and ICAM2). Changes between DCIS and IBC involved around 1000 genes. In tumors, DNA methylation was associated with gene expression of almost 3000 genes (p<0.05, Bonferroni corrected) including both negative and positive correlations. A prognostic signature based on methylation level of 18 CpGs (representing genes such as IRF6, TBX5, ZNF259, KCTD21, EPN3, MACF1 and CSNK1G2) was associated to survival of breast cancer patients with invasive tumors, as well as to survival of patients with DCIS and mixed lesions of DCIS and IBC. This work demonstrates that changes in the epigenome occurs early in the neoplastic progression, provide evidence for the possible utilization of DNA methylation based markers of progression in the clinic, and highlights the importance of epigenetic changes in carcinogenesis. Bisulphite converted DNA from the 285 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip...

  16. Post-transcriptional fine-tuning of COP9 signalosome subunit biosynthesis is regulated by the c-Myc/Lin28B/let-7 pathway ArrayExpress

    ID: E-GEOD-19085

    Description: ubiquitin (Ub) specific protease 15. It regulates cullin-RING Ub ligases (CRLs) that label proteins for proteolysis with poly-Ub chains in the Ub proteasome system (UPS). CRLs contain one of the scaffolding cullins 1 – 7, a RING domain protein e. g. Rbx1, and one of hundreds of substrate binding units such as F-box or BTB proteins that specifically target proteins for ubiquitination. The CSN forms functional supercomplexes with CRLs. It removes the Ub-like prot...

  17. Post-transcriptional fine-tuning of COP9 signalosome subunit biosynthesis is regulated by the c-Myc/Lin28B/let-7 pathway BioProject

    ID: PRJNA120499

    Keywords: Transcriptome or Gene expression

    Access Type: download

  18. Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution PDB

    ID: PDB:5LCW

    Description: E.C.2.7.11.1), Anaphase-promoting complex subunit 7, Mitotic spindle assembly checkpoint protein MAD2A...

  19. Post-transcriptional fine-tuning of COP9 signalosome subunit biosynthesis is regulated by the c-Myc/Lin28B/let-7 pathway OmicsDI

    ID: E-GEOD-19085

    Date Released: 05-02-2014

    Description: ubiquitin (Ub) specific protease 15. It regulates cullin-RING Ub ligases (CRLs) that label proteins for proteolysis with poly-Ub chains in the Ub proteasome system (UPS). CRLs contain one of the scaffolding cullins 1 – 7, a RING domain protein e. g. Rbx1, and one of hundreds of substrate binding units such as F-box or BTB proteins that specifically target proteins for ubiquitination. The CSN forms functional supercomplexes with CRLs. It removes the Ub-like prot...

  20. Selective Degradation of Splicing Factor CAPER-alpha by Anticancer Sulfonamides BioProject

    ID: PRJNA362543

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: articular, the substrate receptor proteins of the cullin ubiquitin ligase system play a key role in selective protein degradation, which is an essential component of the anti-myeloma activity of immunomodulatory drugs (IMiDs) represented by lenalidomide. Here, we demo...

Displaying 20 of 23 results for "CUL7"