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Displaying 15 of 15 results for "CPT1B"
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  1. TXCL1_CALPA UniProt:Swiss-Prot

    ID: P14531

    Description: Delta-hormotoxin-Cpt1b (in Ref. 2; AA sequence)

  2. Epigenetic Dysregulation in the Developing Down Syndrome Brain BioProject

    ID: PRJNA297812

    Keywords: Epigenomics

    Access Type: download

    dataset.description: and growth in cortical neurons. Dysregulation of CPT1B and NOX5 may be associated with mitochondrial dysfunction and increased cell damage in the developing DS brain. Since constitutive hypermethylation of PCDHG and other genes affects multiple tissues, including blood, it may provide useful biomarkers for DS brain development and pharmacologic targets for therapeutic interventions. Overall design: Bisulphite converted DNA from the 72 samples were hybridised to the Illumina HumanMethylation450 BeadChip...
  3. CPT1B_PIG UniProt:Swiss-Prot

    ID: Q8HY46

    Description: Carnitine O-palmitoyltransferase 1, muscle isoform Cytoplasmic Helical Mitochondrial intermembrane Helical Cytoplasmic Coenzyme A binding Proton accep...

    gene.name: CPT1B
  4. CPT1B_RAT UniProt:Swiss-Prot

    ID: Q63704

    Description: Carnitine O-palmitoyltransferase 1, muscle isoform Cytoplasmic Helical Mitochondrial intermembrane Helical Cytoplasmic Coenzyme A binding Proton accep...

    gene.name: Cpt1b
  5. Longissimus Thoracis and subcutaneous fat transcriptome study in lambs BioProject

    ID: PRJNA269055

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: tabolic and lipid process (down-regulated, except CPT1B) (CPT1B, PLA2G16, SPSB1, LRTOMT, PLCD4, FBXO9, CNBP and CYP27A1) and muscle organ differentiation (down-regulated) (CPT1B, MYOD1, MYLK2 and MSTN) in ALF; whereas intracellular signaling cascade (IGF1R, DEF8, AKAP7 and CISH) was down-regulated. In SF, vitamin E supplementation had an important effect; most of the genes were up-regulated. DAVID analysis showed that biosynthesis lipid pathway was the most represented with 20 genes, such as EBP, MVD, CYP51A1, DHCR7, HMGCS1, LSS and FDFT1 implicated in cholesterol synthesis. Further exploration of the links between these genes and vitamin E will lead to a better understanding of how vitamin E affects the oxidative process that occurs in meat products. Overall design: 21 male lambs were employed. 7 animals were fed basal concentrate, 7 animals were fed concentrate supplemented with 500 mg dl-α-tocopheryl acetate/kg concentrate and 7 animals grazed in alfalfa paddocks. Animals were slaughtered at 22-24 kg of live weight. Just after slaughter, a piece of Longissimus Thoracis muscle and a piece of subcutaneous fat were sampled from each animal....
  6. Comparative gene expression profiling between cultured and tissue human skeletal muscle BioProject

    ID: PRJNA118915

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: re genes encoding metabolic proteins AMPD1, PYGM, CPT1B and UCP3, muscle-system proteins TMOD4, MYBPC1, MYOZ1 and XIRP2, the proteolytic CAPN3 and the myogenic regulator MYF6. Within the most upregulated group were genes encoding senescence/apoptosis-related proteins CDKN1A and KIAA1199 and potential regulatory factors HIF1A, TOP2A and CCDC80. In conclusion, cultured muscle cells display reductive metabolic and muscle-system transcriptome adaptations as observed in muscle atrophy and they activate tissue-remodeling and senescence/apoptosis processes. Novel candidate regulators in SM dysfunction are revealed Overall design: 5 biopsies, 5 cell cultures obtained from the biopsies, paired samples. The supplementary file 'GSE17503_non-normalized_data.txt' contains non-normalized data for Samples GSM436162, GSM436164, and GSM436432-GSM436439....
  7. Estrus Synchronization and Ovarian Hyper Stimulation Treatments Have Negligible Effects on Cumulus Oocyte Complexes Gene Expression: Induction of Ovul... ArrayExpress

    ID: E-GEOD-41836

    Description: amino acid degradation and ketogenesis (Hmgcs2 , Cpt1b) were downregulated in G+E+Htrt. These results on rat model show that hormones used for estrus synchronization (Gtrt) and ovarian hyper stimulation (G+Etrt) had minimal effects on gene expression. However, induction of ovulation (G+E+Htrt) caused major changes in gene expression of rat COCs. This study provides comprehensive information about regulated genes during late follicle development and ovulation induction. Four experimental groups were used and there were 6 animals in each group. Total of 24 arrays were used. Only raw data used in publication....

  8. Effects of long-term intake of RPS on gene expression in the colon and liver of pigs ArrayExpress

    ID: E-GEOD-71305

    Description: tomic results showed that the expression of CD36, CPT1B and ACADM was down-regulated, while AGPAT4, GPAT, FABP1 and FABP3 were up-regulated by the RPS diet, indicating a decrease in fatty acid intake and synthesis, and an increase in fatty acid oxidation and glycerophospholipid synthesis.Analysis of the colonic transcriptome profiles revealed that the RPS diet changed the colonic expression profile of the host genes mainly involved in immune response pathways. RPS significantly increased proinflammartory cytokine IL-1β gene expression and suppressed genes involved in lysosome. Thirty-six Duroc × Landrace × Large White growing barrows (70 days of age, 23.78 ± 1.87 kg) were randomly allocated to two groups, each group consisti...

  9. Comparative gene expression profiling between cultured and tissue human skeletal muscle GEMMA

    ID: 1356

    Keywords: functional genomics

    Description: re genes encoding metabolic proteins AMPD1, PYGM, CPT1B and UCP3, muscle-system proteins TMOD4, MYBPC1, MYOZ1 and XIRP2, the proteolytic CAPN3 and the myogenic regulator MYF6. Within the most upregulated group were genes encoding senescence/apoptosis-related proteins CDKN1A and KIAA1199 and potential regulatory factors HIF1A, TOP2A and CCDC80. In conclusion, cultured muscle cells display reductive metabolic and muscle-system transcriptome adaptations as observed in muscle atrophy and they activate tissue-remodeling and senescence/apoptosis processes. Novel candidate regulators in SM dysfunction are revealed Last Updated (by provider): Aug 07 2009 Contributers: Sylviane Metairon Anna-Maria Gomez-Foix Martin Kussmann Andres Nascimento Jaume Colomer Frederic Raymond Celia Garcia-Martinez...

  10. Estrus Synchronization and Ovarian Hyper Stimulation Treatments Have Negligible Effects on Cumulus Oocyte Complexes Gene Expression: Induction of Ovul... BioProject

    ID: PRJNA178294

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: amino acid degradation and ketogenesis (Hmgcs2 , Cpt1b) were downregulated in G+E+Htrt. These results on rat model show that hormones used for estrus synchronization (Gtrt) and ovarian hyper stimulation (G+Etrt) had minimal effects on gene expression. However, induction of ovulation (G+E+Htrt) caused major changes in gene expression of rat COCs. This study provides comprehensive information about regulated genes during late follicle development and ovulation induction. Overall design: Four experimental groups were used and there were 6 animals in each group. Total of 24 arrays were used. Only raw data used in publication....
  11. B6BTBRF2Publish-10023 GeneNetwork

    ID: B6BTBRF2Publish-10023

    Description: Delta Ct numbers of carnitine palmitoyltransferase 1, muscle (Cpt1b) (NM 009948) measured by quatitative real-time RT-PCR

  12. Effects of long-term intake of RPS on gene expression in the colon and liver of pigs BioProject

    ID: PRJNA290868

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: tomic results showed that the expression of CD36, CPT1B and ACADM was down-regulated, while AGPAT4, GPAT, FABP1 and FABP3 were up-regulated by the RPS diet, indicating a decrease in fatty acid intake and synthesis, and an increase in fatty acid oxidation and glycerophospholipid synthesis.Analysis of the colonic transcriptome profiles revealed that the RPS diet changed the colonic expression profile of the host genes mainly involved in immune response pathways. RPS significantly increased proinflammartory cytokine IL-1β gene expression and suppressed genes involved in lysosome. Overall design: Thirty-six Duroc × Landrace × Large White growing barrows (70 days of age, 23.78 ± 1.87 kg) were randomly allocated to two groups, eac...
  13. Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death BioProject

    ID: PRJNA312537

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: oA processing by carnitine palmitoyl transferase (CPT1B) as well as TCA cycle inhibition. We present a model in which hallmarks of acute signaling in HF, including Ca2+ dysregulation and low cAMP levels, are coupled to mitochondrial metabolic and antioxidant defects, through a CREB/PGC1-alpha transcriptional axis. Overall design: 18 total samples were analyzed. The experiment consisted of 3 treatment groups: 1) HYP (ACi-2wk), 2) HF (ACi-4w) 3) SHAM (Shami-4w). Each group consisted of 6 samples. Samples were compared, pairwise using an ANOVA to obtain an estimate of variance, followed by unpaired two-sample t-test using PARTEK Genomics Suite (Genomics Solutions). Specifically comparisons were HYP vs. Sham, HF vs. Sham and HF vs. HYP. False discovery was assessed for named genes by the method of Story (Journal of the Royal Statistical Society: Series B (Statistical Methodology). 2002;64(3):479-98.)...
  14. Estrus Synchronization and Ovarian Hyper Stimulation Treatments Have Negligible Effects on Cumulus Oocyte Complexes Gene Expression: Induction of Ovul... OmicsDI

    ID: E-GEOD-41836

    Date Released: 06-02-2014

    Description: amino acid degradation and ketogenesis (Hmgcs2 , Cpt1b) were downregulated in G+E+Htrt. These results on rat model show that hormones used for estrus synchronization (Gtrt) and ovarian hyper stimulation (G+Etrt) had minimal effects on gene expression. However, induction of ovulation (G+E+Htrt) caused major changes in gene expression of rat COCs. This study provides comprehensive information about regulated genes during late follicle development and ovulation induction. Four experimental groups were used and there were 6 animals in each group. Total of 24 arrays were used. Only raw data used in publication....

  15. Effects of long-term intake of RPS on gene expression in the colon and liver of pigs OmicsDI

    ID: E-GEOD-71305

    Date Released: 08-20-2015

    Description: tomic results showed that the expression of CD36, CPT1B and ACADM was down-regulated, while AGPAT4, GPAT, FABP1 and FABP3 were up-regulated by the RPS diet, indicating a decrease in fatty acid intake and synthesis, and an increase in fatty acid oxidation and glycerophospholipid synthesis.Analysis of the colonic transcriptome profiles revealed that the RPS diet changed the colonic expression profile of the host genes mainly involved in immune response pathways. RPS significantly increased proinflammartory cytokine IL-1β gene expression and suppressed genes involved in lysosome. Thirty-six Duroc × Landrace × Large White growing barrows (70 days of age, 23.78 ± 1.87 kg) were randomly allocated to two groups, each group consisti...


Displaying 15 of 15 results for "CPT1B"