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Displaying 9 of 9 results for "CLN5"
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  1. Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases OmicsDI

    ID: E-MEXP-1333

    Date Released: 09-09-2014

    Description: rom targeted knock out mice produced for Cln1 and Cln5 to explore NCL-associated molecular pathways. Combined microarray datasets from both mouse models exposed a common affected pathway: genes regulating cytoskeletal dynamics and neuronal growth cone stabilization display similar aberrations. We analyzed locus specific gene expression and showed regional clustering of Cln1 and three major genes of this pathway, further supporting a close functional relationship between the corresponding gene products, Cap1, Ptprf and Ptp4a2. The evidence from the gene expre...

  2. Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases ArrayExpress

    ID: E-MEXP-1333

    Description: rom targeted knock out mice produced for Cln1 and Cln5 to explore NCL-associated molecular pathways. Combined microarray datasets from both mouse models exposed a common affected pathway: genes regulating cytoskeletal dynamics and neuronal growth cone stabilization display similar aberrations. We analyzed locus specific gene expression and showed regional clustering of Cln1 and three major genes of this pathway, further supporting a close functional relationship between the corresponding gene products, Cap1, Ptprf and Ptp4a2. The evidence from the gene expre...

  3. Exacerbated neuronal ceroid lipofuscinosos phenotype in Cln1/5 double knock-out mice OmicsDI

    ID: E-GEOD-37643

    Date Released: 11-08-2012

    Description: Both CLN1 and CLN5 deficiency leads to severe neurodegenerative diseases of childhood, known as neuronal ceroid lipofuscinoses (NCL). The broadly...

  4. Exacerbated neuronal ceroid lipofuscinosos phenotype in Cln1/5 double knock-out mice ArrayExpress

    ID: E-GEOD-37643

    Description: Both CLN1 and CLN5 deficiency leads to severe neurodegenerative diseases of childhood, known as neuronal ceroid lipofuscinoses (NCL). The broadly...

  5. Exacerbated neuronal ceroid lipofuscinosos phenotype in Cln1/5 double knock-out mice BioProject

    ID: PRJNA162369

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Both CLN1 and CLN5 deficiency leads to severe neurodegenerative diseases of childhood, known as neuronal ceroid lipofuscinoses (NCL). The broadly...
  6. CLN5_BOVIN UniProt:Swiss-Prot

    ID: Q1ZYR0

    Description: Ceroid-lipofuscinosis neuronal protein 5 N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-li...

    gene.name: CLN5
  7. CLN5_SHEEP UniProt:Swiss-Prot

    ID: A2TJ54

    Description: Ceroid-lipofuscinosis neuronal protein 5 N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-li...

    gene.name: CLN5
  8. CLN5B_DICDI UniProt:Swiss-Prot

    ID: Q54WC3

    Description: Cln5-like protein 2 N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-link...

  9. CLN5C_DICDI UniProt:Swiss-Prot

    ID: Q54C37

    Description: Cln5-like protein 3 Helical Poly-Gly N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (GlcNAc...) N-linked (...


Displaying 9 of 9 results for "CLN5"