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Displaying 20 of 64 results for "CLDN8"
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  1. CLD8_MOUSE UniProt:Swiss-Prot

    ID: Q9Z260

    Description: Claudin-8 Cytoplasmic Helical Extracellular Helical Cytoplasmic Helical Extracellular Helical Cytoplasmic Intera...

  2. Gene Expression Profiling Separates Chromophobe Renal Cell Carcinoma from Oncocytoma BioProject

    ID: PRJNA113527

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: as also performed for two selected gene products, Claudin 8 and MAL2....
  3. Transcription profiling by array of human chromophobe renal cell carcinoma and oncocytoma ArrayExpress

    ID: E-GEOD-12090

    Description: as also performed for two selected gene products, Claudin 8 and MAL2....

  4. Diarrhea in lymphocytic colitis: ERK1/2-dependent ENaC dysregulation and claudin-4-, -5- and -8-related barrier defects BioProject

    ID: PRJNA273003

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Structure of Clostridium perfringens Enterotoxin with a peptide derived from a modified version of ECL-2 of Claudin 2 PDB

    ID: PDB:4P5H

    Description: Claudin-2, Heat-labile enterotoxin B chain

  6. Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer (miRNA expression data). BioProject

    ID: PRJNA178026

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer (mRNA expression data). BioProject

    ID: PRJNA177639

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer (aCGH data). BioProject

    ID: PRJNA177952

    Keywords: Variation

    Access Type: download

  9. The Tight Junction Protein Claudin-2 Controls Mucosal Permeability, Immune Tolerance and Colitis in Mice BioProject

    ID: PRJNA196867

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasion ArrayExpress

    ID: E-GEOD-26055

    Description: on and function. Previous studies have shown that claudin-7 is frequently upregulated in epithelial ovarian cancer (EOC) along with claudin-3 and claudin-4. Here, we investigate in detail the expression patterns of

  11. Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasion BioProject

    ID: PRJNA135561

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Knockout mice reveal key roles for claudin-18 in alveolar fluid homeostasis ArrayExpress

    ID: E-GEOD-48443

    Description: Claudin proteins are major constituents of epithelial and endothelial tight junctions (TJ), where they serve as regulators of parac...

  13. Metastatic Cascade is Reflected in the Gene Expression of Metastatic Canine Mammary Carcinomas Similar to Human Breast Cancer ArrayExpress

    ID: E-GEOD-22516

    Description: GFR, KRT17, MAP2K6, STAT5), cell adhesion (CLDN5, CLDN8, CTNNAL1, MCAM, MUC1, PECAM1) and angiogenesis (ANGPT2, ANGPTL1, ANGPTL2, ANGPTL4, FGFR1, FIGF, TIE1) were mostly down-regulated. Interestingly, tumors had a significant decrease in membrane receptors and growth factor pathway gene expression (EGFR, FGFR1, GHR, LYVE1, PDGFR, PDGFR, TGFBR, TIE1), indicating a potential independence from these proliferative stimuli. Several of the identified deregulated pathways overlap with gene expression profiles of human breast cancer. Gene expression profiling of metastatic carcinomas therefore identified complex molecular pathways and functional gene families that are deregulated during malignant progression in the tumors. This study provides new insights into canine mammary tumor metastasis and suggests that canine mammary tumors may serve as a valuable model for the human disease. 13 simple mammary carcinomas with lymph node metastases at the time of tumor resection were compared with the non-neoplastic mammary gland of the same dogs. Sufficient amounts of normal mammary gland were not available for dogs no. 1 (822) and 9 (61). In addition, one normal sample without matching tumor sample was analyzed (no. 8; 2609). All patients had no radiographically detectable pulmon...

  14. Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasion OmicsDI

    ID: E-GEOD-26055

    Date Released: 10-01-2012

    Description: on and function. Previous studies have shown that claudin-7 is frequently upregulated in epithelial ovarian cancer (EOC) along with claudin-3 and claudin-4. Here, we investigate in detail the expression patterns of

  15. Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4-alpha cascades BioProject

    ID: PRJNA330979

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4-alpha cascades OmicsDI

    ID: E-GEOD-84742

    Date Released: 07-31-2016

    Description: Analysis of the complex expression of claudin genes and transcription factors during intestinal epithelial cell differentiation across the crypt-to-surface colonic axis....

  17. epithelial cells from mice expressing transgenic claudin-2 and wild type controls with or without dextran sodium sulfate (DSS)-induced colitis... OmicsDI

    ID: E-GEOD-46006

    Date Released: 04-30-2015

    Description: sociated with mucosal inflammation. Expression of claudin-2, a pore-forming tight junction protein, is highly upregulated during inflammatory bowel disease (IBD) and, due to its association with epithelial permeability, has been postulated to promote inflammation. Furthermore, claudin-...

  18. epithelial cells from mice expressing transgenic claudin-2 and wild type controls with or without dextran sodium sulfate (DSS)-induced colitis... ArrayExpress

    ID: E-GEOD-46006

    Description: sociated with mucosal inflammation. Expression of claudin-2, a pore-forming tight junction protein, is highly upregulated during inflammatory bowel disease (IBD) and, due to its association with epithelial permeability, has been postulated to promote inflammation. Furthermore, claudin-...

  19. Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer (miRNA expression data) ArrayExpress

    ID: E-GEOD-41723

    Description: s consist of 2 normal tissues, 7 MMTV-Met tumors, 8 MMTV-Met;Trp53fl/+;Cre tumors, and 8 Trp53;Cre tumors....

  20. Madin Darby Canine Kidney (MDCK) Cells: Early & Late Passage ArrayExpress

    ID: E-GEOD-14837

    Description: tinin (PNA), a decrease in steady state levels of claudin-1 and a slight decrease in E-cadherin expression in the context of an apparently claudin-2-negative system. Late passage cells grew in more densely packed monolayers and exhibited characteristics of a competent, functional cultured monolayer including inducible vectorial ion transport in response to norepinephrine (NE) and sphere formation in three dimensional laminin gel culture. Microarray analysis of gene expression levels in early and late passage cells revealed an increase in transcript abundance for SGK and GLUT-3, and a reduction Id-3. The steady state protein expression levels of GLUT-3, however, were found to be equivalent. These findings suggest that the expression of claudin-2 in MDCK cells could be contingent on signaling via lateral cell contacts...


Displaying 20 of 64 results for "CLDN8"