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Displaying 20 of 71 results for "CLDN5"
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  1. CLD5_BOVIN UniProt:Swiss-Prot

    ID: Q2HJ22

    Description: Claudin-5 Cytoplasmic Helical Extracellular Helical Cytoplasmic Helical Extracellular Helical Cytoplasmic Intera...

  2. Knockout mice reveal key roles for claudin-18 in alveolar fluid homeostasis ArrayExpress

    ID: E-GEOD-48443

    Description: Claudin proteins are major constituents of epithelial and endothelial tight junctions (TJ), where they serve as regulators of parac...

  3. Knockout mice reveal key roles for claudin-18 in alveolar fluid homeostasis. BioProject

    ID: PRJNA210147

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Diarrhea in lymphocytic colitis: ERK1/2-dependent ENaC dysregulation and claudin-4-, -5- and -8-related barrier defects BioProject

    ID: PRJNA273003

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Knockout mice reveal key roles for claudin-18 in alveolar fluid homeostasis. OmicsDI

    ID: E-GEOD-48443

    Date Released: 06-03-2014

    Description: Claudin proteins are major constituents of epithelial and endothelial tight junctions (TJ), where they serve as regulators of parac...

  6. Genes up-regulated by VE-cadherin expression and clustering at junctions GEMMA

    ID: 1633

    Keywords: functional genomics

    Description: al genes up-regulated by VE-cadherin, among which claudin-5 reached remarkably high levels. The up-regulation of these genes required not only VE-cadherin expression but also cell confluence suggesting that VE-cadherin clustering at junctions was needed. Last Updated (by provider): Mar 15 2009 Contributers: Ferruccio Breviario Fabrizio Orsenigo Annarita Conti Elisabetta Dejana Andrea Taddei...

  7. Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasion BioProject

    ID: PRJNA135561

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasion ArrayExpress

    ID: E-GEOD-26055

    Description: on and function. Previous studies have shown that claudin-7 is frequently upregulated in epithelial ovarian cancer (EOC) along with claudin-3 and claudin-4. Here, we investigate in detail the expression patterns of

  9. Transcription profiling of mouse VE-cadherin null cell line vs contrik ArrayExpress

    ID: E-GEOD-11674

    Description: al genes up-regulated by VE-cadherin, among which claudin-5 reached remarkably high levels. The up-regulation of these genes required not only VE-cadherin expression but also cell confluence suggesting that VE-cadherin clustering at junctions was needed. Experiment Overall Design: VEC null or positive cells in the sparse and confluent conditions have been starved in MCDB 131 medium 1% BSA for 36 h. Next, RNA has been extracted with standard guanidinium isothiocyanate lysis buffer and cesium chloride ultracentrifugation. Synthesis of biotinylated cRNA targets, array hybridization (GeneChips MG_U74Av2 and MG_U74Bv2), staining and scanning were performed according to the Affymetrix standard protoco...

  10. Isolation of subtype-specific N-Ras responsive genes in basal-like breast cancer cells ArrayExpress

    ID: E-GEOD-61768

    Description: epress N-RAS in basal-like SUM102PT, SUM149PT and claudin-low SUM159PT cells. We seek the genes regulated only in basal-like, but not in claudin-low cells, to isolate the genes controlled by N-Ras in a breast cancer subtype-specific fashion. We...

  11. Isolation of subtype-specific N-Ras responsive genes in basal-like breast cancer cells BioProject

    ID: PRJNA262083

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: epress N-RAS in basal-like SUM102PT, SUM149PT and claudin-low SUM159PT cells. We seek the genes regulated only in basal-like, but not in claudin-low cells, to isolate the genes controlled by N-Ras in a breast cancer subtype-specific fashion. We...
  12. supplementary files for figures Figshare

    ID: doi:10.6084/M9.FIGSHARE.4508786.V1

    Release Date: 01-01-2017

    Description: induction for figure 1.Excel 3: Data of occludin 5, ZO-1 AND claudin-5 protein levels in cortex after sham or subarachnoid hemorrhage induction with deferoxamine (DFX) treatment or vehicle at day 3 for figure 3.Excel 4: Data of ferritin heavy chain (FTH) and light chain (FTL) protein levels in cortex at day 3 after sha...

  13. Isolation of subtype-specific N-Ras responsive genes in basal-like breast cancer cells OmicsDI

    ID: E-GEOD-61768

    Date Released: 06-13-2015

    Description: epress N-RAS in basal-like SUM102PT, SUM149PT and claudin-low SUM159PT cells. We seek the genes regulated only in basal-like, but not in claudin-low cells, to isolate the genes controlled by N-Ras in a breast cancer subtype-specific fashion. We...

  14. supplementary files for figures Figshare

    ID: doi:10.6084/M9.FIGSHARE.4508786

    Release Date: 01-01-2017

    Description: induction for figure 1.Excel 3: Data of occludin 5, ZO-1 AND claudin-5 protein levels in cortex after sham or subarachnoid hemorrhage induction with deferoxamine (DFX) treatment or vehicle at day 3 for figure 3.Excel 4: Data of ferritin heavy chain (FTH) and light chain (FTL) protein levels in cortex at day 3 after sha...

  15. Genes up-regulated by VE-cadherin expression and clustering at junctions BioProject

    ID: PRJNA106073

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: al genes up-regulated by VE-cadherin, among which claudin-5 reached remarkably high levels. The up-regulation of these genes required not only VE-cadherin expression but also cell confluence suggesting that VE-cadherin clustering at junctions was needed. Overall design: VEC null or positive cells in the sparse and confluent conditions have been starved in MCDB 131 medium 1% BSA for 36 h. Next, RNA has been extracted with standard guanidinium isothiocyanate lysis buffer and cesium chloride ultracentrifugation. Synthesis of biotinylated cRNA targets, array hybridization (GeneChips MG_U74Av2 and MG_U74Bv2), staining and scanning were performed according to the Affymetrix standard protocols, startin...
  16. Expression data for human epithelium from subjects with atopic dermatitis, psoriasis and nonatopic controls BioProject

    ID: PRJNA136959

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: d function of tight junction genes, in particular claudin-1, was studied in order to further understanding of the biology underlying atopic dermatitis. Overall design: Gene expression profiling was ...
  17. Expression data for human epithelium from subjects with atopic dermatitis, psoriasis and nonatopic controls ArrayExpress

    ID: E-GEOD-26952

    Description: d function of tight junction genes, in particular claudin-1, was studied in order to further understanding of the biology underlying atopic dermatitis. Gene expression profiling was performed on tot...

  18. Cell culture of p63 knock out and wild type bladder epithelial stem cell BioProject

    ID: PRJNA282371

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: . From wild type bladder, we have cloned keratin 5-positive stem cells, and from p63 knockout epithelium, which loses basal cell fraction, we have cloned morphologically-distinct keratin 8 and claudin 3 positive stem cells, which may be reminiscent of intestinal metaplasia in bladder. Overall design: From newborn mice (p63 knockout and wild type), bladder were collected and digested with collagenase for stem cell culture. Epithelial stem cells were cultured on 3T3 feeder cells. Colonies of epithelial stem cells from p63 knockout and wild t...
  19. Characterization of human breast cancer xenografts BioProject

    ID: PRJNA139023

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: tumor subtype (Basal-like, Luminal A, Luminal B, Claudin-low, HER2+/ER- and Normal breast-like). [1] Dabney AR (2005) Classification of microarrays to nearest centroids. Bioinformatics 21:4148-4154. [2] Herschkowitz JI, et al. (2007) Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 8:R76. Overall design: Total RNA obtained from xenograft tumors from 5 different patients have been profiled in triplicate on the Illumina HT-12 BeadChip platform....
  20. on identifies trophoblast invasion-related genes: Claudin-4 and Fucosyltransferase IV control mobility via altering matrix metalloproteinase activity... ArrayExpress

    ID: E-GEOD-60885

    Description: K-treated EVT. Among these genes, CLDN4 (encoding claudin-4) and FUT4 (encoding fucosyltranferase IV) were chosen for follow-up studies because of the biological relevance found in the research on tumor cells. The results showed that the mRNA and protein expressions of both CLDN4 and FUT4 in dNK-treated EVT were significantly reduced, and were inversely correlated with DNA methylation. Knocking down CLDN4 and FUT4 by siRNA reduced trophoblast invasion, possibly through the altered MMP-2 and/or MMP-9 expression and activity. Taken together, dNK alter EVT mobility at least partially in association with an alteration of DNA methylation profile. Hypermethylation of CLDN4 and FUT4 reduce protein expressions. CLDN4 and FUT4 are representative genes that participate in modulating trophoblast mobility. This studied analyzed 17 samples of placental villous explant cultre exposed to different growt...


Displaying 20 of 71 results for "CLDN5"