CLASP1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 177 results for "CLASP1"
i
  1. A Cryptic TOG Domain with a Distinct Architecture Underlies CLASP-Dependent Bipolar Spindle Formation PDB

    ID: PDB:4K92

    Description: CLIP-associating protein 1

  2. CLAP1_XENTR UniProt:Swiss-Prot

    ID: A1A5G0

    Description: CLIP-associating protein 1 HEAT 1 HEAT 2 HEAT 3 HEAT 4 HEAT 5 HEAT 6 HEAT 7 HEAT 8 Ser-rich

  3. LN28A_HUMAN UniProt:Swiss-Prot

    ID: Q9H9Z2

    Description: Removed Protein lin-28 homolog A CSD CCHC-type 1 CCHC-type 2 Flexible linker N-acetylglycine Phosphos...

  4. NTAL_CHICK UniProt:Swiss-Prot

    ID: Q5S7W5

    Description: Linker for activation of T-cells family member 2 Extracellular Helical; Signal-anchor for type III membrane protein

  5. Nuclear Envelope Retention of LINC Complexes Is Promoted by SUN-1 Oligomerization in the Caenorhabditis elegans Germ Line BioProject

    ID: PRJNA308570

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Gene expression profiling in ovarian cancer ArrayExpress

    ID: E-GEOD-63885

    Description: me group or on the independent group of patients. CLASP1 was the only gene that was found to be important for DFS in the independent group, whereas in the preceding experiments it showed associations with other clinical endpoints and with BRCA1 gene mutation; thus, it may be worthy of further testing. Our results confirm that histological tumor type may be a strong confounding factor and we conclude that gene expression studies of ovarian carcinomas should be performed on histologically homogeneous groups. Among the reasons of poor reproducibility of statistical results may be the fact that despite relatively large patients’ group, in some analyses one has to compare small and unequal classes of samples. In addition, arbitrarily performed division of samples into classes compared may not always reflect their true biological diversity. And finally, we think that clinical endpoints of the tumor probably depend on subtle changes in many and, possibly, alternative molecular pathways, and such changes may be difficult to demonstrate. Here, we provide gene expression data from 101 ovarian cancer surgical samples: 73 serous, 12 endometrioid, 9 clear cell and 7 undifferentiated. The majority of patients (98 out of 101) were tested for BRCA1 gene mutation: ...

  7. Chromatin-associated protein kinase C-0 regulates an inducible gene expression program and microRNAs in human T lymphocytes ArrayExpress

    ID: E-GEOD-26035

    Description: onstrated that signalling kinases with well known cytoplasmic functions have a surprisingly active role in the nucleus, where they are tethered to chromatin and modulate gene expression programs. Here we pr...

  8. Chromatin-associated protein kinase C-0 regulates an inducible gene expression program and microRNAs in human T lymphocytes BioProject

    ID: PRJNA135505

    Keywords: Epigenomics

    Access Type: download

  9. Chromatin-associated protein kinase C-0 regulates an inducible gene expression program and microRNAs in human T lymphocytes OmicsDI

    ID: E-GEOD-26035

    Date Released: 05-02-2014

    Description: onstrated that signalling kinases with well known cytoplasmic functions have a surprisingly active role in the nucleus, where they are tethered to chromatin and modulate gene expression programs. Here we pr...

  10. AN EXAMINATION OF THE HONG KONG AIRPORT THIRD RUNWAY PROJECT (HKATRP) USING THE MODE 2 STRATEGIC ASSUMPTIONS AND SURFACING TECHNIQUE (SAST) RATIONALE Figshare

    ID: doi:10.6084/M9.FIGSHARE.1618695

    Release Date: 12-08-2015

    Description:

  11. Solution structure of the 1st CAP-Gly domain in human CLIP-115/CYLN2 PDB

    ID: PDB:2CP2

    Description: CLIP-115

    datasetDistributions.storedIn: Protein Data Bank
  12. Solution structure of the 2nd CAP-Gly domain in human CLIP-115/CYLN2 PDB

    ID: PDB:2CP3

    Description: CLIP-115

    datasetDistributions.storedIn: Protein Data Bank
  13. Gene expression profiling in ovarian cancer BioProject

    ID: PRJNA269331

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: me group or on the independent group of patients. CLASP1 was the only gene that was found to be important for DFS in the independent group, whereas in the preceding experiments it showed associations with other clinical endpoints and with BRCA1 gene mutation; thus, it may be worthy of further testing. Our results confirm that histological tumor type may be a strong confounding factor and we conclude that gene expression studies of ovarian carcinomas should be performed on histologically homogeneous groups. Among the reasons of poor reproducibility of statistical results may be the fact that despite relatively large patients’ group, in some analyses one has to compare small and unequal classes of samples. In addition, arbitrarily performed division of samples into classes compared may not always reflect their true biological diversity. And finally, we think that clinical endpoints of the tumor probably depend on subtle changes in many and, possibly, alternative molecular pathways, and such changes may be difficult to demonstrate. Overall design: Here, we provide gene expression data from 101 ovarian cancer surgical samples: 73 serous, 12 endometrioid, 9 clear cell and 7 undifferentiated. The majority of patients (98 out of 101) were tested for BRCA1...
  14. Expression profiling of NM1 KO and WT mice BioProject

    ID: PRJNA305129

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: endocytosis and exocytosis. Unconventional class 1 myosins are potent regulators of plasma membrane tension because they physically link the plasma membrane with the adjacent cytoskeleton. We identified nuclear myosin 1 (NM1) - a putative nuclear isoform of myosin 1c (Myo1c) - as a new player in t...
  15. Expression profiling of NM1 KO and WT mice ArrayExpress

    ID: E-GEOD-75709

    Description: endocytosis and exocytosis. Unconventional class 1 myosins are potent regulators of plasma membrane tension because they physically link the plasma membrane with the adjacent cytoskeleton. We identified nuclear myosin 1 (NM1) - a putative nuclear isoform of myosin 1c (Myo1c) - as a new player in t...

  16. Transcriptome analysis of monocytic leukemia cell differentiation ArrayExpress

    ID: E-GEOD-1865

    Description: is of gene expression (SAGE) and developed a SADE linker-anchored PCR assay to investigate the pattern of expression of known genes and to identify new transcripts in proliferating cells and during cell growth arrest and differentiation. We implemented new informatic tools to compare expression profiles before and after exposure of cells...

  17. Solution NMR Structure of Microtubule-associated serine/threonine-protein kinase 1 from Homo sapiens, Northeast Structural Genomics... PDB

    ID: PDB:2M9X

    Description: Microtubule-associated serine/threonine-protein kinase 1 (E.C.2.7.11.1)

  18. PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1 PDB

    ID: PDB:3PS4

    Description: ---

  19. The mammalian LINC complex controls mechanosensing at a genome-wide level: miRNA-sequencing BioProject

    ID: PRJNA310700

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: clear organelles and cause direct dissociation of protein complexes inside nuclei. Yet, the extent to which such signals impact gene expression is not understood. Because mechanical forces from the cytoskeleton to the nucleus interior are transmitted by the LINC (linker of nucleoskeleton-to-cytoskeleton) complex, we disrupted the LINC complex and performed genome wide expression studies using RNA sequencing. LINC disruption altered the expression of hundreds of genes at a genome-wide scale. We asked how LINC disruption affected the mechanosensitivity of i...
  20. The mammalian LINC complex controls mechanosensing at a genome-wide level: RNA-Seq BioProject

    ID: PRJNA310599

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: clear organelles and cause direct dissociation of protein complexes inside nuclei. Yet, the extent to which such signals impact gene expression is not understood. Because mechanical forces from the cytoskeleton to the nucleus interior are transmitted by the LINC (linker of nucleoskeleton-to-cytoskeleton) complex, we disrupted the LINC complex and performed genome wide expression studies using RNA sequencing. LINC disruption altered the expression of hundreds of genes at a genome-wide scale. We asked how LINC disruption affected the mechanosensitivity of i...

Displaying 20 of 177 results for "CLASP1"