CDKL5 | bioCADDIE Data Discovery Index
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Displaying 20 of 147 results for "CDKL5"
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  1. ell clones expressing either wild-type or mutated CDKL5 gene to study the gene's role in transcriptional regulation... ArrayExpress

    ID: E-MTAB-2223

    Description: Mutations in the human CDKL5 gene have been associated with early onset seizure variant of Rett Syndrome. In order to investigate the potential involvemen...

  2. Transcription profiling by array of human clonal primary fibroblasts from patients with CDKL5 mutations ArrayExpress

    ID: E-MEXP-2833

    Description: Mutations in the human CDKL5 gene have been shown to cause infantile spasms, as well as Rett syndrome-like phenotype. Because CDKL5 is ...

  3. Crystal structure of the human CDKL5 kinase domain PDB

    ID: PDB:4BGQ

    Description: CYCLIN-DEPENDENT KINASE-LIKE 5 (E.C.2.7.11.22)

  4. ell clones expressing either wild-type or mutated CDKL5 gene to study the gene's role in transcriptional regulation... OmicsDI

    ID: E-MTAB-2223

    Date Released: 06-03-2014

    Description: Mutations in the human CDKL5 gene have been associated with early onset seizure variant of Rett Syndrome. In order to investigate the potential involvemen...

  5. Transcription profiling by array of human clonal primary fibroblasts from patients with CDKL5 mutations OmicsDI

    ID: E-MEXP-2833

    Date Released: 06-03-2014

    Description: Mutations in the human CDKL5 gene have been shown to cause infantile spasms, as well as Rett syndrome-like phenotype. Because CDKL5 is ...

  6. Sequential elution interactome analysis of Mind bomb 1 and a novel role in dendritic spine outgrowth OmicsDI

    ID: PXD001255

    Date Released: 07-06-2016

    Description: delta-catenins; regulators of Wnt signaling; and CDKL5, which is mutated in EIEE2, a severe form of mental retardation. We demonstrated that Mib1 downregulates CDKL5, limits its effects on dendritic spine outgrowth, and inhibits spine outgrowth itself. These data further elaborate upon the signaling networks and biological functions influenced by this critical protein and expand our understanding of the signaling networks involved in neuronal development....

  7. De novo genic mutations among a Chinese autism spectrum disorder cohort NIMH

    ID: doi:10.15154/1252218

    Release Date: 01-30-2017

    attributes.description: implicated in ASD (ARHGAP32, NCOR1, PHIP, STXBP1, CDKL5 and SHANK1). Patient follow-up confirms phenotypic features associated with the genetic subtypes and highlights how large global cohorts might be leveraged to identify individually rare mutations in genes that together prove pathogenic significance....
  8. GDC-0941 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1046

    protein.name: CDKL5
  9. CGP60474 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1040

    protein.name: CDKL5
  10. LY-317615 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1140

    protein.name: CDKL5
  11. Gefitinib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1142

    protein.name: CDKL5
  12. HG-14-10-04 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1120

    protein.name: CDKL5
  13. ABT-869 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1163

    protein.name: CDKL5
  14. INCB018424 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1154

    protein.name: CDKL5
  15. VX-745 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1159

    protein.name: CDKL5
  16. AT-7519 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1172

    protein.name: CDKL5
  17. GW843682 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1018

    protein.name: CDKL5
  18. CEP-701 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1170

    protein.name: CDKL5
  19. Dabrafenib KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1117

    protein.name: CDKL5
  20. ZM-447439 KINOMEscan LINCS

    Data Type: Binding Protein binding profile

    Assay: KINOMEscan kinase-small molecule binding assay

    Biological Process: Small molecule metabolic process

    ID: LDS-1033

    protein.name: CDKL5

Displaying 20 of 147 results for "CDKL5"