CDK10 | bioCADDIE Data Discovery Index
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Displaying 20 of 152 results for "CDK10"
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  1. CDK10_BOVIN UniProt:Swiss-Prot

    ID: Q2TBL8

    Description: Cyclin-dependent kinase 10 Protein kinase ATP Proton ac...

  2. CDK10_RAT UniProt:Swiss-Prot

    ID: Q4KM47

    Description: Cyclin-dependent kinase 10 Protein kinase ATP Proton ac...

  3. Comparative genomic hybridization of frozen salivary or pulmonary adenoid cystic carcinoma samples and normal tissue to identify copy number alteratio... ArrayExpress

    ID: E-TABM-267

    Description: cancer genes, including TP53, CDKN2A/CDKN2B, SKI, CDK10, and VEGF. CDK10 was the only oncogene that localized to the MCR of gain at 16q24.1-24.3. In addition, we identified LIMA1 as the sole putative tumor suppressor gene residing in the MCR of deletion at 12q12q12-13.2. Among well defined and narrow, but unique alterations, there were gains harboring MDM2, cyclin D1, and KIT, as well as one loss involving the hsa-mir-124a-2 miRNA. Using immunohistochemistry, we found abnormal protein expression in the cases with gain of cyclin D1 or MDM2. In conclusion, the majority of previousl...

  4. Cdk10KO mouse tissues BioProject

    ID: PRJNA385774

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: To study the function of Cdk10 in the developing mouse embryo, we isolated eight tissues [heart, brain, liver, stomach, thymus, lung, spleen, kidney, intest...
  5. Comparative genomic hybridization of frozen salivary or pulmonary adenoid cystic carcinoma samples and normal tissue to identify copy number alteratio... OmicsDI

    ID: E-TABM-267

    Date Released: 05-02-2014

    Description: cancer genes, including TP53, CDKN2A/CDKN2B, SKI, CDK10, and VEGF. CDK10 was the only oncogene that localized to the MCR of gain at 16q24.1-24.3. In addition, we identified LIMA1 as the sole putative tumor suppressor gene residing in the MCR of deletion at 12q12q12-13.2. Among well defined and narrow, but unique alterations, there were gains harboring MDM2, cyclin D1, and KIT, as well as one loss involving the hsa-mir-124a-2 miRNA. Using immunohistochemistry, we found abnormal protein expression in the cases with gain of cyclin D1 or MDM2. In conclusion, the majority of previousl...

  6. CDK10_DICDI UniProt:Swiss-Prot

    ID: Q55GS4

    Description: Probable cyclin-dependent kinase 10 Protein kinase ATP Asn-rich ...

  7. CDK1_ORYCU UniProt:Swiss-Prot

    ID: Q9DGA5

    Description: Cyclin-dependent kinase 1 Protein kinase ATP Proton acceptor ATP Phosphoth...

  8. CDK1_ORYLU UniProt:Swiss-Prot

    ID: Q9DG98

    Description: Cyclin-dependent kinase 1 Protein kinase ATP Proton acceptor ATP Phosphoth...

  9. P27(KIP1)/CYCLIN A/CDK2 COMPLEX PDB

    ID: PDB:1JSU

    Description: CYCLIN-DEPENDENT KINASE-2, CYCLIN A, P27

  10. Crystal Structure of Pho85-Pcl10 Complex PDB

    ID: PDB:4KRD

    Description: Cyclin-dependent protein kinase PHO85 (E.C.2.7.11.22), PHO85 cyclin-

  11. HUMAN CYCLIN-DEPENDENT KINASE 2 PDB

    ID: PDB:1HCK

    Description: HUMAN CYCLIN-DEPENDENT KINASE 2, ADENOSINE-5'-TRIPHOSPHATE

  12. Crystal Structure of Pho85-Pcl10-ATP-gamma-S Complex PDB

    ID: PDB:4KRC

    Description: Cyclin-dependent protein kinase PHO85 (E.C.2.7.11.22), PHO85 cyclin-

  13. STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis Figshare

    ID: doi:10.6084/M9.FIGSHARE.3141727.V1

    Release Date: 03-30-2016

    Description:

  14. CDN1B_CANLF UniProt:Swiss-Prot

    ID: Q6SLL5

    Description: Cyclin-dependent kinase inhibitor 1B Nuclear localization signal Phosphoserine; by UHMK1 Phos...

  15. Expression data from human corneal endothelial cells BioProject

    ID: PRJNA144299

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: he corneal stroma, mainly through the Na+- and K+-dependent ATPase (Na+/K+-ATPase). Because HCEC proliferative activity is low in vivo,we tried to activate proliferation of HCEC by inhibiting cyclin-dependent kinase inhibitors.We have here demonstrated microarray data of transduced human corneal endothelial cell lines. Overall design: Affy...
  16. p53 family members in myogenic differentiation and rhabdomyosarcoma development BioProject

    ID: PRJNA96121

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: s the retinoblastoma gene, p63 and p73 induce the cyclin-dependent kinase inhibitor p57 to maintain RB in an active, hypophosphorylated state. DeltaNp73 inhibits these functions of the p53 family in differentiation control, prevents myogenic differentiation, and enables cooperating oncogenes to transform myoblasts to tumorigenicity. DeltaNp73 is frequently overexpressed in rhabdomyosarcoma and essential for tumor progression in vivo. These findings establish differentiation control as a key tumor...
  17. Cyclin-dependent kinase 6 is a chromatin-bound cofactor for nuclear factor kappaB-dependent gene expression [ChIP-Seq] BioProject

    ID: PRJNA229063

    Keywords: Epigenomics

    Access Type: download

  18. The dependency of cpr5-altered genes on SIM and SMR1 in Arabidopsis ArrayExpress

    ID: E-GEOD-40322

    Description: A genetic screen revealed that the Cip/Kip CKIs (cyclin-dependent kinase inhibitors), SIM (siamese) and SMR1 (siamese-related 1), are essential for CPR5 signaling, as the sim smr1 double mutant fully suppressed the cpr5 phenotype. More significantly, PCD and ETI are compromised in sim smr1 even with the wild-type CPR5. 10-day-old wild type (Col-0), cpr5, sim smr1 and cpr5 sim smr1. 12 samples total. Replicates are derived from three independent biological experiments. We used microarrays to identify differentially expressed genes. We focused on those genes that were cpr5-altered (>2-fold) and SIM/SMR1-dependent...

  19. MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression ArrayExpress

    ID: E-GEOD-14831

    Description: ers multiple targets of the family, including the cyclin-dependent kinase inhibitor p21/CDKN1A. We show that p21 is a direct target of miR-106b and that its silencing plays a key role in miR-106b-induced cell cycle phenotypes. We also show that miR-106b overrides a doxorubicin-induced DNA damage checkpoint. Thus, miR-106b family members contribute to tumor cell proliferation in part by regulating cell cycle progression and by modulating checkpoint functions. HCT116 Dic...

  20. Shp2 Signaling Suppresses Senescence in PyMT-induced Mammary Gland Cancer in Mice [Mouse430_2 array] ArrayExpress

    ID: E-GEOD-50517

    Description: tion of senescence-associated β-gal (SA-β-gal), cyclin-dependent kinase inhibitor 1B (p27), p53, and histone 3 trimethylated lysine 9 (H3K9me3). Senescence induction leads to inhibition of self-renewal of tumor cells and blockage of tumor formation and growth. A signaling cascade was identified that acts downstream of Shp2 to counter senescence: Src, Focal adhesion kinase and Map kinase inhibit...


Displaying 20 of 152 results for "CDK10"