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Displaying 10 of 10 results for "CDH19"
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  1. Identification of Novel Cholesteatoma-related Gene Expression Signatures Using Full-genome Microarrays OmicsDI

    ID: E-GEOD-42256

    Date Released: 05-03-2014

    Description: steatoma. 334 genes were down-regulated more than 2-fold. Significantly regulated genes with protein metabolism activity include matrix metalloproteinases as well as PI3, SERPINB3 and SERPINB4. Genes like SPP1, KRT6B, PRPH, SPRR1B and LAMC2 are known as genes with cell growth and/or maintenance activity. Transport activity genes and signal transduction genes are LCN2, GJB2 and CEACAM6. The three cell communication genes are CDH19 and genes belonging to the S100 family. Two samples from each patient (cholesteatoma vs. normal auditory canal skin) for each two-colour hybridisation experiment...

  2. Identification of Novel Cholesteatoma-related Gene Expression Signatures Using Full-genome Microarrays ArrayExpress

    ID: E-GEOD-42256

    Description: steatoma. 334 genes were down-regulated more than 2-fold. Significantly regulated genes with protein metabolism activity include matrix metalloproteinases as well as PI3, SERPINB3 and SERPINB4. Genes like SPP1, KRT6B, PRPH, SPRR1B and LAMC2 are known as genes with cell growth and/or maintenance activity. Transport activity genes and signal transduction genes are LCN2, GJB2 and CEACAM6. The three cell communication genes are CDH19 and genes belonging to the S100 family. Two samples from each patient (cholesteatoma vs. normal auditory canal skin) for each two-colour hybridisation experiment...

  3. Transcription profiling of human Schwann cells FROM HMSN1A, HMSN-LOM AND congenital cateracts facial dysmophism neuropathy (CCFDN) syndrome TO ident... OmicsDI

    ID: E-GEOD-7423

    Date Released: 05-02-2014

    Description: expression signatures specific for each genotype. 2. Genes commonly (dys)regulated in all screened neuropathies. Interestingly, these include genes that play a role in reorganization of sodium channels in central and peripheral nerves (S100A10, CD90), or extracellular matrix remodeling (e.g. TGFBI, SERPINE1, THBS1). We also found high up-regulation of genes involved in Schwann cell lineage and in particular, genes that are associated with an immature or pre-myelinating Schwann cell phenotype (i.e. Sox2, Sox10, COL18A1, TFAP2A, Pax3, CDH19). Our study shows that many genes, possibly contributing to nerve pathology can be identified by this approach. Experiment Overall Design: Experimental design: in total 12 (two-color) arrays were run. All neuropathy samples were in duplicate (technical replicates). Two CCFDN and two HMSN1A patients were also analyzed as biological replicates. Three healthy subjects were included from which one was in duplicate. All samples (Cy3) were compared to a common reference pool (Cy5) which consisted of a mix of all samples....

  4. Transcription profiling of human Schwann cells FROM HMSN1A, HMSN-LOM AND congenital cateracts facial dysmophism neuropathy (CCFDN) syndrome TO ident... ArrayExpress

    ID: E-GEOD-7423

    Description: expression signatures specific for each genotype. 2. Genes commonly (dys)regulated in all screened neuropathies. Interestingly, these include genes that play a role in reorganization of sodium channels in central and peripheral nerves (S100A10, CD90), or extracellular matrix remodeling (e.g. TGFBI, SERPINE1, THBS1). We also found high up-regulation of genes involved in Schwann cell lineage and in particular, genes that are associated with an immature or pre-myelinating Schwann cell phenotype (i.e. Sox2, Sox10, COL18A1, TFAP2A, Pax3, CDH19). Our study shows that many genes, possibly contributing to nerve pathology can be identified by this approach. Experiment Overall Design: Experimental design: in total 12 (two-color) arrays were run. All neuropathy samples were in duplicate (technical replicates). Two CCFDN and two HMSN1A patients were also analyzed as biological replicates. Three healthy subjects were included from which one was in duplicate. All samples (Cy3) were compared to a common reference pool (Cy5) which consisted of a mix of all samples....

  5. Identification of Novel Cholesteatoma-related Gene Expression Signatures Using Full-genome Microarrays BioProject

    ID: PRJNA179448

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: steatoma. 334 genes were down-regulated more than 2-fold. Significantly regulated genes with protein metabolism activity include matrix metalloproteinases as well as PI3, SERPINB3 and SERPINB4. Genes like SPP1, KRT6B, PRPH, SPRR1B and LAMC2 are known as genes with cell growth and/or maintenance activity. Transport activity genes and signal transduction genes are LCN2, GJB2 and CEACAM6. The three cell communication genes are CDH19 and genes belonging to the S100 family. Overall design: Two samples from each patient (cholesteatoma vs. normal auditory canal skin) for each two-colour hybridisa...
  6. CADH7_CHICK UniProt:Swiss-Prot

    ID: Q90763

    Description: Cadherin-7 Extracellular Helical Cytoplasmic Cadherin 1 Cadherin 2

  7. Down-stream effects in demyelinating neuropathies BioProject

    ID: PRJNA97857

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: expression signatures specific for each genotype. 2. Genes commonly (dys)regulated in all screened neuropathies. Interestingly, these include genes that play a role in reorganization of sodium channels in central and peripheral nerves (S100A10, CD90), or extracellular matrix remodeling (e.g. TGFBI, SERPINE1, THBS1). We also found high up-regulation of genes involved in Schwann cell lineage and in particular, genes that are associated with an immature or pre-myelinating Schwann cell phenotype (i.e. Sox2, Sox10, COL18A1, TFAP2A, Pax3, CDH19). Our study shows that many genes, possibly contributing to nerve pathology can be identified by this approach. Keywords: disease state analysis, genotype down-stream effects analysis Overall design: Experimental design: in total 12 (two-color) arrays were run. All neuropathy samples were in duplicate (technical replicates). Two CCFDN and two HMSN1A patients were also analyzed as biological replicates. Three healthy subjects were included from which one was in duplicate. All samples (Cy3) were compared to a common reference pool (Cy5) which consisted of a mix of all samples....
  8. Expression of microRNAs and their gene targets are dysregulated in pre-invasive breast cancer (microRNA) BioProject

    ID: PRJNA133521

    Keywords: Other

    Access Type: download

    dataset.description: creased the expression of CBX7 (which regulates E-cadherin expression), DOK4, NMT2, and EGR1. Augmentation of CBX7 by knockdown of miR-182 expression, in turn, positively regulated the expression of E-cadherin, a key protein involved in maintaining normal epithelial cell morphology which is commonly lost during neoplastic progression. Conclusions: These data provide the first miRNA expression profile of normal breast epithelium and of pre-invasive breast carcinoma. Further, we demonstrate that altered miRNA expression can modulate gene expression changes that characterize these early cancers. We conclude that miRNA dysregulation likely plays a substantial role in early breast cancer development. Overall design: The expression of 365 microRNAs were measured in 19 total samples via multiplex reverse transcription PCR using the TaqMan Human MicroRNA Low Density Array. Patients age ranged from 42-75. Equal amounts of total RNA from 9 reduction mammoplasty samples (age range 42-75) were combined into a pooled RM control (PRM), this sample was run in triplicate. Remaining 16 samples consist of matched samples of ductal carcinoma in situ and adjacent histologically normal breast epithelium, these are identified by case number and histologic lesion....
  9. Cell Image Library Dataset CIL:39002 CIL

    ID: 39002

    Description: he tube. The blue stain shows the location of the cadherin 7 mRNA in the neural crest migrating down alongside the neural tube and in an intense band across the centre of the neural tube. Cadherin 7 is a transmembrane protein that affects cell-cell adherance....

    Data Types: image

  10. miRNA-mediated expression switch of cell adhesion genes driven by microcirculation in chip BioProject

    ID: PRJNA322822

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ip. We identified 7 up-regulated CAM genes (CD44, CDH7, CEACAM5, CEACAM6, CYR61, L1CAM and VCAN), 7 down-regulated genes (COL12A1, FGA, FGB, FGG, GJA1, ITGA5 and LAMA1) and 69 miRNAs targeting them under the influence of microcirculation. The revealed network comprised CAM genes known to interact with each other and 13 miRNAs simultaneously regulating more than one of them. Overall design: Undifferentiated Caco2 cells were seeded on individual polyether membrane inserts with 0.143 cm2 surface area and 1.0 μm pore diameter, cut out from HTS Transwell®-96 well permeable support (Corning Inc., USA), with cell density approximately 60,000 cells/well. The cells were ...

Displaying 10 of 10 results for "CDH19"