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Displaying 20 of 87 results for "CCNB1"
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  1. ulated restriction of the exit from pluripotency (CCNB1 overexpression)... ArrayExpress

    ID: E-GEOD-63215

    Description: nd neuroectodermic genes. Total RNA obtained from CCNB1 overexpressing hESCs incubated in medium without bFGF and TGF-beta for 0, 48 and 96 hours....

  2. ulated restriction of the exit from pluripotency (CCNB1 overexpression)... BioProject

    ID: PRJNA266997

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. ulated restriction of the exit from pluripotency (CCNB1 overexpression)... OmicsDI

    ID: E-GEOD-63215

    Date Released: 08-19-2015

    Description: nd neuroectodermic genes. Total RNA obtained from CCNB1 overexpressing hESCs incubated in medium without bFGF and TGF-beta for 0, 48 and 96 hours....

  4. Identification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors [ChIP-se... ArrayExpress

    ID: E-GEOD-52098

    Description: ber of cell cycle genes including PLK, AURKB, and CCNB1. FOXM1 ChIP-seq in asynchronous HeLa cells...

  5. Human CDK1/CyclinB1/CKS2 With Inhibitor PDB

    ID: PDB:4Y72

    Description: Human CDK1 (E.C.2.7.11.22), Cyclin B1, CKS2

    gene.name: CCNB1, CCNB
  6. Ternary complex of human proteins CDK1, Cyclin B and CKS2, bound to an inhibitor PDB

    ID: PDB:5HQ0

    Description: Cyclin-dependent kinase 1 (E.C.2.7.11.22,2.7.11.23), G2/mitotic-specific cyclin-B1, Cyclin-dependent kinases regulatory subunit 2

    gene.name: CCNB1, CCNB
  7. RAS signaling in colon carcinoma: Target gene deregulation and growth control through Y-box-binding protein 1 ArrayExpress

    ID: E-GEOD-18232

    Description: n reporter gene assays by using a fragment of the CCNB1 promoter as a model. We discovered YBX1 to be associated with the endogenous CCNB1 promoter and the promoters of 62 additional genes within the proliferation associated gene groups by a ChIP-on-chip assay. Silencing of YBX1 expression by siRNA prevents CCNB1 expression and partially inhibits proliferation of HCT116 cells. In view of multiple known YBX1 functions in stress response, chromatin remodeling, transcriptional and translational regulation, our results indicate that this factor may also contribute to RAS-induced pleiotropic effects in cancer. The cells were treated with certain inhibitors for 48 hours. We used one sample per cell line treated with DMSO as a control, and one sample for each of the treatments....

  8. RAS signaling in colon carcinoma: Target gene deregulation and growth control through Y-box-binding protein 1 OmicsDI

    ID: E-GEOD-18232

    Date Released: 06-02-2014

    Description: n reporter gene assays by using a fragment of the CCNB1 promoter as a model. We discovered YBX1 to be associated with the endogenous CCNB1 promoter and the promoters of 62 additional genes within the proliferation associated gene groups by a ChIP-on-chip assay. Silencing of YBX1 expression by siRNA prevents CCNB1 expression and partially inhibits proliferation of HCT116 cells. In view of multiple known YBX1 functions in stress response, chromatin remodeling, transcriptional and translational regulation, our results indicate that this factor may also contribute to RAS-induced pleiotropic effects in cancer. The cells were treated with certain inhibitors for 48 hours. We used one sample per cell line treated with DMSO as a control, and one sample for each of the treatments....

  9. Gene expression signatures for bladder cancer tissues and normal adjacent tissues ArrayExpress

    ID: E-GEOD-45184

    Description: xpression of six mRNAs and lincRNAs (E2F1, CCNE2, CCNB1, lincRNA:chr1:205404014-205407007, lincRNA:chr7:130723313-130727663, lincRNA:chr4:15669186-15683175) from this signature was quantified in the same RNA samples by real-time PCR, confirming good quality of the microarray analysis. Data in the matrix are log2 transformed. Three pairs of fresh frozen bladder cancer tissues and corresponding normal adjacent tissues were used in the microarray analysis....

  10. Identification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors [ChIP-se... BioProject

    ID: PRJNA226675

    Keywords: Epigenomics

    Access Type: download

    dataset.description: ber of cell cycle genes including PLK, AURKB, and CCNB1. Overall design: FOXM1 ChIP-seq in asynchronous HeLa cells...
  11. CCNB1_ANGJA UniProt:Swiss-Prot

    ID: Q60FY0

    Description: G2/mitotic-specific cyclin-B1

    gene.name: ccnb1
  12. CCNB1_RAT UniProt:Swiss-Prot

    ID: P30277

    Description: G2/mitotic-specific cyclin-B1 Interaction with CDK2 Interaction with CDK2 Lys-rich Phosphoserine; by CDK1 Phosphoserine Phosphoserine; by PLK1 Phospho...

    gene.name: Ccnb1
  13. CCNB1_CARAU UniProt:Swiss-Prot

    ID: Q92162

    Description: G2/mitotic-specific cyclin-B1

    gene.name: ccnb1
  14. CCNB1_BOVIN UniProt:Swiss-Prot

    ID: Q1LZG6

    Description: G2/mitotic-specific cyclin-B1 Interaction with CDK2 Interaction with CDK2 Lys-rich N6-acetyllysine Phosphoserine; by CDK1 Phosphoserine Phosphoserine;...

    gene.name: CCNB1
  15. CCNB1_ORYLU UniProt:Swiss-Prot

    ID: Q9DG97

    Description: G2/mitotic-specific cyclin-B1

    gene.name: ccnb1
  16. CCNB1_MESAU UniProt:Swiss-Prot

    ID: P37882

    Description: G2/mitotic-specific cyclin-B1 Interaction with CDK2 Interaction with CDK2 N6-acetyllysine Phosphoserine; by CDK1 Phosphoserine Phosphoserine; by PLK1 ...

    gene.name: CCNB1
  17. CCNB1_CRIGR UniProt:Swiss-Prot

    ID: Q08301

    Description: G2/mitotic-specific cyclin-B1 Interaction with CDK2 Interaction with CDK2 Lys-rich N6-acetyllysine Phosphoserine; by CDK1 Phosphoserine Phosphoserine;...

    gene.name: CCNB1
  18. CCNB1_ORYJA UniProt:Swiss-Prot

    ID: Q9DGA0

    Description: G2/mitotic-specific cyclin-B1

    gene.name: ccnb1
  19. CCNB1_ORYCU UniProt:Swiss-Prot

    ID: Q9DGA4

    Description: G2/mitotic-specific cyclin-B1

    gene.name: ccnb1
  20. Chip-on-chip analysis of direct Nkx2.1 target genes in proliferating and differentiating epithelium in mouse lung development ArrayExpress

    ID: E-GEOD-23043

    Description: de proliferation related genes such as E2F3, Met, Ccnb1, and Ccnb2. Nkx2.1 downregulation in mouse epithelial and human carcinoma cell lines reduced cell proliferation by arresting cells in the G2/M phase. Reduced expression of Nkx2.1 target genes in both cell lines supports a direct role of Nkx2.1 in regulation of cell proliferation genes. The identification of these transcriptional regulatory pathways in vivo aid us to understand Nkx2.1 function in lung development and link it to disease, since many of the identified targets are aberrantly up regulated in cancer cells. Developing mouse lung, 2 developmental time points E11.5 and E19.5, genomic DNA fragments immunoprecipitated with a-Nkx2.1 (07-601, Upstate-Millipore) vs input, E11.5, 2 biological replicates and E19.5, 3 biological replicates...


Displaying 20 of 87 results for "CCNB1"