CCNA1 | bioCADDIE Data Discovery Index
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Displaying 8 of 8 results for "CCNA1"
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  1. CCNA1_RAT UniProt:Swiss-Prot

    ID: Q6AY13

    Description: Cyclin-A1

    gene.name: Ccna1
  2. CCNA1_XENLA UniProt:Swiss-Prot

    ID: P18606

    Description: Cyclin-A1

    gene.name: ccna1
  3. Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits β-catenin degradation BioProject

    ID: PRJNA178411

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: on of several genes regulated by β-catenin (e.g. CCNA1, CCNE2, WISP1, ID4, SFN, ME1) that may help to explain altered tumor growth and metastasis. In conclusion, these results provide the first evidence for TSPAN12 playing a role in supporting primary tumor growth and suppressing metastasis. TSPAN12 appears to function by stabilizing FZD4-LRP5 association, in support of canonical Wnt-pathway signaling, leading to enhanced β-catenin expression and function. Overall design: 4 samples = 2 Control + 2 TSPAN12KD...
  4. Expression data from 22 human myotubes ArrayExpress

    ID: E-GEOD-44874

    Description: Expression data from 22 human myotubes (7 healthy controls, 4 Dysferlinopathy (DYSF), 4 Caveolinopathy 3 (CAV3), 4 Facioscapulohumeral muscular dystr...

  5. Expression data from 22 human myotubes BioProject

    ID: PRJNA192214

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. cAMP Ca2+ NFAT signalling in RPTEC control vs. CAA BioProject

    ID: PRJNA96707

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: DK5, IL2, PLN, SRF, GCG, SGK, JUNB, BDNF, S100A6, CCNA1, MIF, HK2, SST and EGR2 by CAA was observed in two independent experiments. From the AP-1 family expression of junD and fosB were not altered. Overexpression by CAA of CREB and DDIT3 were only observed in one of two experiments. JUND, FOSB, FOSL1, CREM and CREBBP expression was not influenced in reproducible manner, as well as all members of the NFAT-family. In the Ca2+/NFAT-Arrays, PPP3CB, VAV3, NFATC1, IL8, IL6, FASLG, IL3, IFNB1, FOS, BCL2, EGR3, CD3G, HRAS, EP300, IL4, CALM3, RELA, EGR2, NPPB, IFNG, NFATC4, KPNA5, CAMK2BNFKB2 , VEGF, IL8RA, IL2,GATA4, MEF2A, PTPRC, ICOS, NFKBIE, CDKN1A, CSNK2B, ACTB, MEF2B and JUNB mRNA´s were repeatedly reduced by CAA exposure. The only gene with upregulation in both experiments was found to be IFN-alpha. Thus CAA exposure f...
  7. Transcription profiling of human Hela CD4+ cells transfected with epitope tagged eTat or parental vector to identify therapeutic targets for HIV-1 inf... ArrayExpress

    ID: E-GEOD-6431

    Description: Despite the success of Highly Active Anti-Retroviral Therapy (HAART), patients often stop treatment due to the inception of side effects. Furthermore,...

  8. Cytoscan HD arrays data for Nodal marginal zone lymphoma (NMZL) BioProject

    ID: PRJNA281882

    Keywords: Variation

    Access Type: download

    dataset.description: ing CDKN2A, PARK2, PARKG (9%), CDC16, CDCA2 (6%), CCNA1, CCNT2, CDK5, CDK13, CDK20, BTG2, HECA and PLK2 (3%). Most (71%) NMZL harbored genetic lesions affecting epigenetic modifiers (MLL2: 34%; CREBBP: 9%; EP300: 6%; TRRAP: 6%), histones (20%) or transcriptional co-repressors (TBL1XR1: 14%; ARID1A: 14%; RCOR1: 11%; NCOR2: 9%, ARID1B: 9%). Finally, the TNFRSF14 and FAS genes, involved in T cell-mediated tumor surveillance, were disrupted by mutations and/or deletions in 17% and 14% NMZL, respectively. A number of actionable cellular programs are molecularly deregulated in NMZL, including JAK/STAT, NOTCH, NF-κB and TLR signaling, cell cycle and chromatin remodeling. PTPRD lesions are among the most recurrent alterations in NMZL and appear to be specific for this lymphoma type across mature B-cell tumors. Cytoscan HD arrays (Affymetrix, Santa Clara, CA) experiments were performed according to the manufacturer's directions on DNA extracted from cryopreserved diagnostic samples. Overall design: Copy number aberration analysis of Cytoscan HD arrays (Affymetrix) was performed for 35 NMZL samples. Paired normal (non-tumoral) DNA samples were available for 23 out of 35 NMZL patients that were analyzed and processed....

Displaying 8 of 8 results for "CCNA1"