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Displaying 20 of 1,147 results for "CAPRIN1"
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  1. Crystal structure of the HR-1 domain of human caprin-1 in the P3121 space group PDB

    ID: PDB:4WBP

    Description: Cytoplasmic activation/proliferation-associated protein...

  2. Crystal structure of the HR-1 domain of human caprin-1 in the C121 space group PDB

    ID: PDB:4WBE

    Description: Cytoplasmic activation/proliferation-associated protein...

  3. Distinct translational control in CD4+ T-cell subsets ArrayExpress

    ID: E-GEOD-45401

    Description: on-studies have defined canonical signatures of T-cell subsets. Changes in steady-state mRNA levels do, however, often not reflect those of corresponding proteins due to post-transcriptional mechanisms including mRNA translation. Here, we unveil a unique translational signature, contrasting CD4+Foxp3+ regulatory T (TFoxp3+) and CD4+Foxp3- non-regulatory T (TFoxp3-) cells, which i...

  4. Gene expression of rat uterine endometrial stromal cells treated with ethanol (vehicle) or 0.1 nM progestin R5020 BioProject

    ID: PRJNA242117

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: changes that take place as a consequence of their activation. Progesterone controls proliferation of rat endometrial stromal cells during the peri-implantation phase of pregnancy. We showed that picomolar concentration of progestin R5020 mimics this control in UIII endometrial stromal cells via ER...
  5. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts [PAR-CLIP] ArrayExpress

    ID: E-GEOD-38201

    Description: Protein-RNA interactions are fundamental to core biological processes, such as mRNA splicing, localization, degradation and transla...

  6. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly BioProject

    ID: PRJNA308553

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: s a previously unidentified mediator of mTORC1 on protein synthesis and proliferation. In addition, we demonstrate a formerly undocumented role for CK2 in regulation of translation initiation, whereby CK2 stimulates phosphorylation of eIF2β and simultaneously bolsters eIF4F complex assembly via the mTORC1/4E-BP pathway. These findings imply a previously unrecognized mode of translation regulation whereby mTORC1 and CK2 coordinate TC and eIF4F complex assembly to stimulate cell proliferation. Overall design: Comparisons of polysome-associated and cytoplasmic mRNA from starved cells or cells stimulated with insulin in the presence or absence of Torin-1....
  7. A Phase 2 Study of Tipifarnib in Large Granular Lymphocyte (LGL) Leukemia dbGaP

    ID: phs000594.v1.p1

    Description: LGL leukemia can be divided into three subsets including the following: αβ or γδT-LGL and NK-LGL leukemia. All three subtypes will...

    studyGroup.Identifier: 1
  8. The PKA Pathway of Endometrial Stromal Fibroblasts Reveals Differentiation and Proliferative Potential in Endometriosis BioProject

    ID: PRJNA118917

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: hout (hESFnon-endo) endometriosis, in response to activation of the PKA pathway with 8-Br-cAMP. hESFnon-endo (n=4) and hESFendo (mild endometriosis, n=4) were isolated from eutopic endometrium and treated +/- 0.5mM 8-Br-cAMP for 96 hours. Purified total RNA was subjected to microarray analysis using the whole genome Gene 1.0 ST Affymetrix platform. 733 genes were regulated in cAMP-treated hESFnon-endo versus 172 genes in hESFendo, suggesting a b...
  9. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts [PAR-CLIP] BioProject

    ID: PRJNA167443

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. CDCA3_XENLA UniProt:Swiss-Prot

    ID: P0C2X8

    Description: Cell division cycle-associated protein 3 F-box-like KEN box

  11. CDCA3_RAT UniProt:Swiss-Prot

    ID: Q68FW2

    Description: Cell division cycle-associated protein 3 F-box-like KEN box Phosphoserine ...

  12. Major Depressive Disorder blood gene expression ArrayExpress

    ID: E-GEOD-19738

    Description: n age 41.9 years)), we identified a set of genes (CAPRIN1, CLEC4A, KRT23, MLC1, PLSCR1, PROK2, ZBTB16) that serves as a molecular signature of MDD. These findings were validated for the primary cohort using an independent quantitative PCR method (P = 0.007). The difference between depressive patients and controls was confirmed (P = 0.019) in a replication cohort of 13 patients with MDD (mean age 42.8 years) and 14 controls (mean age 45.6 years). The MDD-signature score comprised of expression levels of 7 genes could discriminate depressive patients from controls with sensitivity of 76.9% and specificity of 71.8%. Conclusions: We show for the first time that molecular analysis of stimulated blood cells can be used as an endophenotype for MDD diagnosis, which is a milestone in establishing biomarkers for neuropsychiatric disorders with moderate heritability in general. Our results may provide a new entry point for following and predict...

  13. CDCA2_BOVIN UniProt:Swiss-Prot

    ID: Q29RT4

    Description: Cell division cycle-associated protein 2 PP1-binding Lys-rich Phosphoserin...

  14. Crystal structure of zebrafish Caprin-2 C1q domain PDB

    ID: PDB:4OUS

    Description: Caprin-2

  15. Crystal structure of human Caprin-2 C1q domain PDB

    ID: PDB:4OUM

    Description: Caprin-2

  16. Proliferating normal human peripheral blood mononuclear cells infected with HIV type 1 RF BioProject

    ID: PRJNA85235

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Effect of PTP inhibition on changes in gene expression after Cr(VI) exposure BioProject

    ID: PRJNA113435

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ough the consequences of genotoxic injury include cell cycle arrest and apoptosis, cell survival responses after genotoxic injury can produce intri...
  18. FTSQ_ECOLI UniProt:Swiss-Prot

    ID: P06136

    Description: Cell division protein FtsQ Cytoplasmic Helical Periplasmic POTRA No change in activity. Corre...

  19. STRUCTURE OF AURORA-A 122-403, PHOSPHORYLATED ON THR287, THR288 AND BOUND TO TPX2 1-43 PDB

    ID: PDB:1OL5

    Description: NE KINASE 6 (E.C.2.7.1.37), RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100...

  20. Crystal structure of human Caprin-2 C1q domain PDB

    ID: PDB:4OUL

    Description: Caprin-2


Displaying 20 of 1,147 results for "CAPRIN1"