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Displaying 20 of 92 results for "BUB1"
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  1. Structure of Bub1 kinase domain PDB

    ID: PDB:4QPM

    Description: Mitotic checkpoint serine/threonine-protein kinase

  2. Crystal structure of the conserved N-terminal domain of the mitotic checkpoint component BUB1 PDB

    ID: PDB:3ESL

    Description: Checkpoint serine/threonine-protein kinase BUB1

  3. Solution NMR Structure of Mitotic checkpoint serine/threonine-protein kinase PDB

    ID: PDB:2LAH

    Description: Mitotic checkpoint serine/threonine-protein kinase

  4. Structure and substrate recruitment of the human spindle checkpoint kinase bub1 PDB

    ID: PDB:4R8Q

    Description: Mitotic checkpoint serine/threonine-protein kinase

  5. Structure of human Bub1 kinase domain phosphorylated at Ser969 PDB

    ID: PDB:5DMZ

    Description: Mitotic checkpoint serine/threonine-protein kinase

  6. Kinetochore-BUBR1 kinase complex PDB

    ID: PDB:3SI5

    Description: Mitotic checkpoint serine/threonine-protein kinase

  7. The crystal structure of the human Bub1 TPR domain in complex with the KI motif of Knl1 PDB

    ID: PDB:4A1G

    Description: MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE

  8. CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF BUBR1 PDB

    ID: PDB:2WVI

    Description: MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE

  9. some (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution... PDB

    ID: PDB:5KHU

    Description: subunit 2, Anaphase-promoting complex subunit 5, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (E.C.2.7.11.1), Cell division cycle protein 20 homolog, Mitotic spindle assembly checkpoint protein MAD2A, unknown, Anaphase-promoting complex subunit 7...

  10. Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 4.2 angstrom resolution PDB

    ID: PDB:5LCW

    Description: ubunit 5, Cell division cycle protein 20 homolog, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (E.C.2.7.11.1), Anaphase-promoting complex subunit 7, Mitotic spindle assembly checkpoint protein MAD2A...

  11. Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. PDB

    ID: PDB:4GGD

    Description: Cell division cycle protein 20 homolog, Mitotic checkpoint serine/threonine-protein kinase

  12. Crystal structure of yeast Bub3-Bub1 bound to phospho-Spc105 PDB

    ID: PDB:4BL0

    Description: CELL CYCLE ARREST PROTEIN BUB3, CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 (E.C.2....

  13. Bub3 complex with Bub1 GLEBS motif PDB

    ID: PDB:2I3S

    Description: Cell cycle arrest protein BUB3, Checkpoint serine/threonine-protein kinase BUB1 (E.C.2....

  14. Expression profiling of MRC5 senescent fibroblasts ArrayExpress

    ID: E-GEOD-15919

    Description: pathways, cell cycle (PKMYT1, CDC7, CCNE2, MCM4, BUB1, CDC25A, CDKN1B, MCM6, PLK1, CDKN2C, CCNB2, MCM3, BUB1B, CCNA2, CDC2), cytokine-cytokine receptor interaction (KITLG, IL11, TNFSF4, CCL2, PDGFRA, TNFRSF11B, TGFBR1, IL1R1, TNFRSF19), and DNA replication (POLE, RFC2, MCM4, RNASEH2B, POLA1, DNA2, MCM6, PRIM1, RFC4, MCM3). Along with p53 transcriptional targets (CDKN1A, PERP, WIG1), genes encoding secreted factors (WNT16, MMP10, MMP3) were among the most strongly increased in senescent cells. Six arrays were hybridized with complex probes consisting of RNA isolated from MRC5 fibroblasts at population doubling 63 (undergoing replicative senescence) and RNA isolated from MRC5 fibroblats at population doubling 28 (young). The six arrays correspond to three biological replicates, each with a dye-swap technical replicate....

  15. Expression profiling of MRC5 senescent fibroblasts BioProject

    ID: PRJNA116923

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: pathways, cell cycle (PKMYT1, CDC7, CCNE2, MCM4, BUB1, CDC25A, CDKN1B, MCM6, PLK1, CDKN2C, CCNB2, MCM3, BUB1B, CCNA2, CDC2), cytokine-cytokine receptor interaction (KITLG, IL11, TNFSF4, CCL2, PDGFRA, TNFRSF11B, TGFBR1, IL1R1, TNFRSF19), and DNA replication (POLE, RFC2, MCM4, RNASEH2B, POLA1, DNA2, MCM6, PRIM1, RFC4, MCM3). Along with p53 transcriptional targets (CDKN1A, PERP, WIG1), genes encoding secreted factors (WNT16, MMP10, MMP3) were among the most strongly increased in senescent cells. Overall design: Six arrays were hybridized with complex probes consisting of RNA isolated from MRC5 fibroblasts at population doubling 63 (undergoing replicative senescence) and RNA isolated from MRC5 fibroblats at population doubling 28 (young). The six arrays correspond to three biological replicates, each with a dye-swap technical replicate....
  16. Effects of soy supplementation on gene expression in breast cancer ArrayExpress

    ID: E-GEOD-58792

    Description: promote cell proliferation, such as FGFR2, E2F5, BUB1, CCNB2, MYBL2, CDK1, and CDC20 (P < .01). Soy intake did not result in statistically significant changes in Ki67 or Cas3. Conclusions Gene expression associated with soy intake and high plasma genistein define a signature characterized by overexpression of FGFR2 and genes that drive cell cycle and proliferation pathways. These findings raise the concerns that in a subset of women soy could adversely affect gene expression in breast cancer. Genome-wide expression analysis was performed on breast cancer tissue from women following treatment with soy (n=28) or placebo (n=23)....

  17. Mus musculus strain:Bub1b H/H or Trisomy 19 : Single cell sequencing of Bub1bH/H tissues and sequencing of trisomy 19 blood cell population BioProject

    ID: PRJNA322660

    Keywords: genome sequencing

    Access Type: download

  18. Effects of soy supplementation on gene expression in breast cancer BioProject

    ID: PRJNA253495

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: promote cell proliferation, such as FGFR2, E2F5, BUB1, CCNB2, MYBL2, CDK1, and CDC20 (P < .01). Soy intake did not result in statistically significant changes in Ki67 or Cas3. Conclusions Gene expression associated with soy intake and high plasma genistein define a signature characterized by overexpression of FGFR2 and genes that drive cell cycle and proliferation pathways. These findings raise the concerns that in a subset of women soy could adversely affect gene expression in breast cancer. Overall design: Genome-wide expression analysis was performed on breast cancer tissue from women following treatment with soy (n=28) or placebo (n=23)....
  19. Chromosomal abnormalities in hepatic cysts point to novel polycystic liver disease genes ArrayExpress

    ID: E-GEOD-78808

    Description: events: a 2q13 complex rearrangement resulting in BUB1 haploinsufficiency, a 47XXX karyotype, chromosome 9q copy number loss, and LOH on chromosome 3p. The latter region was overlapping with an LOH region identified in two other cysts. Unique germline and somatic abnormalities occur frequently in and outside of known genes underlying cysts. Each liver cyst has a unique genetic makeup. LOH driver gene BUB1 may imply germline causes of genetic instability in PLD. 24 liver cysts from 23 patients...

  20. miR-10b*, a master inhibitor of the cell cycle, is downregulated in human breast tumors ArrayExpress

    ID: E-GEOD-40525

    Description: and in vivo three novel target mRNAs of miR-10b*, BUB1, PLK1 and CCNA2 genes, which play a remarkable role in cell cycle regulation and whose high expression in breast cancer patients reduced disease free survival, relapse free survival and metastasis free survival when compared to low expressors. This also suggests that restoration of microRNA-10b* expression might bear therapeutic promise. In exploring the potential involvement of miRs in breast tumorigenesis, we profiled the miRs expression of 64 primary breast cancer patients, comprising 56 matched tumor and adjacent peritumoral breast tissues, 5 tumor and 3 peritumor unmatched tissues, using the Agilent microarray platform. For 14 samples technical replicate were also performed....


Displaying 20 of 92 results for "BUB1"