BHMT | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 16 of 16 results for "BHMT"
i
  1. BHMT FROM RAT LIVER PDB

    ID: PDB:1UMY

    Description: BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE (E.C.2.1.1.5)

  2. BHMT1_XENLA UniProt:Swiss-Prot

    ID: Q5XGM3

    Description: Betaine--homocysteine S-methyltransferase 1 Hcy-binding Zinc Zinc Zinc

    gene.name: bhmt
  3. BHMT1_PIG UniProt:Swiss-Prot

    ID: Q95332

    Description: Removed Betaine--homocysteine S-methyltransferase 1 Hcy-binding Zinc N6-succinyllysine N6-succinyllysine N6-succinyllysine N6-succinyllysine N6-succin...

    gene.name: BHMT
  4. BHMT1_PONAB UniProt:Swiss-Prot

    ID: Q5RFG2

    Description: Removed Betaine--homocysteine S-methyltransferase 1 Hcy-binding Zinc Zinc Zinc N6-succinyllysine N6-succinyllysine N6-succinyllysine N6-succinyllysine...

    gene.name: BHMT
  5. Betaine-Homocysteine S-Methyltransferase from Homo sapiens complexed with Homocysteine PDB

    ID: PDB:4M3P

    Description: Betaine--homocysteine S-methyltransferase 1 (E.C.2.1.1.5)

    gene.name: BHMT
  6. Comparative transcriptome analysis on alteration of gene expression in ayu (Plecoglossus altivelis) larvae associated with salinity change BioProject

    ID: PRJNA296594

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: MC), betaine--homocysteine S-methyltransferase 1 (BHMT), fructose-bisphosphate aldolase B (aldolase B), tyrosine aminotransferase (TAT), and Na+-K+ ATPase (NKA) were up-regulated after FW acclimation. Furthermore, the mRNA expressions of b-type natriuretic peptide (BNP) and transgelin were down-regulated after FW acclimation. In conclusion, our data indicate that FW acclimation reduces the growth rate of ayu larvae, which may result from the expression alteration of genes related to endocrine hormones, energy metabolism, and direct osmoregulation. Overall design: Ayu larvae were kept in BW or FW tanks at 20–22 °C in a recirculating system with filtered water after hatching, and fed with commercial pellets once a day. Groups of 20 fish each were subjected to BW (containing 0.17 M NaCl, 10 ppt) in four tanks (BW group) or to FW in the other four tanks (FW group)....
  7. CCAAT/Enhancer Binding Proteins (C/EBP)-α and -β are Essential for Ovulation, Luteinization and the Expression of Key Target Genes OmicsDI

    ID: E-GEOD-23084

    Date Released: 06-02-2014

    Description: ncluding effectors of vascular cell development. Bhmt, a gene controlling methionine metabolism and expressed exclusively in liver and kidney, was high in WT luteal cells but totally absent in Cebpa/b mutant cells. Because numerous genes potentially associated with vascular development were suppressed in the mutant cells, C/EBPa/b appear to dictate the luteinization process by also controlling genes that regulate the formation of the extensive vascular network required to sustain luteal cells. Thus, C/EBPa/b mediate several aspects of granulosa cell differentiation as well as the complex process of luteinization. Five granulosa cell treatments were included: CEBPα/β conditional KO ovary, eCG-treated 48h, hCG 4h wild type ovary, eCG-treated 48h, hCG 8h CEBPα/β conditional KO ovary, eCG-treated 48h, hCG 8h wild type ovary, eCG-treated 48h, hCG 24h CEBPα/β conditional KO ovary, eCG-treated 48h, hCG 24h...

  8. Identification of novel biomarker candidates for the immunohistochemical diagnosis of cholangiocellular carcinoma - LC-MS Part OmicsDI

    ID: PXD000534

    Date Released: 07-21-2014

    Description: ) and Betaine-homocysteine S-methyltransferase 1 (BHMT) were significantly down-regulated. Furthermore, STIP1 and SFN were able to differentiate between CCC tumour cells and non-tumorous cholangiocytes with a sensitivity of 100% and 86%, respectively and a specificity of 100% in both cases. We therefore conclude that these proteins should be considered as potential diagnostic biomarkers for CCC in an immunohistochemical application. Additional experiments addressing the validation of these novel biomarker candidates are being performed....

  9. Transcriptional Response to Sulfur Limitation in Pelagibacter ubique OmicsDI

    ID: E-GEOD-31630

    Date Released: 07-03-2016

    Description: nfirmed S-adenosyl methionine (SAM) riboswitches: bhmT, mmuM, and metY. These genes were up to 33 times more abundant during low DMSP conditions and shunt all available sulfur to methionine. The osmotically inducible organic hydroperoxidase OsmC was the most up-regulated protein as DMSP (an osmolyte) became scarce. The second response, during sulfur-depleted stationary phase, saw increased transcription of the heme c shuttle ccmC and two small genes of unknown function (SAR11_1163 and SAR11_1164) which were 6-10 times higher in sulfur-starved cultures. No known membrane transporters were up-regulated in response to sulfur limitation, suggesting that this bacterium's strategy for coping with sulfur stress focuses on intracellularly redistributing, rather than importing, organic sulfur compounds. This supports the conclusion that the few organosulfur molecules that Ca. P. ubique is able to metabolize are rarely limiting in the marine environment....

  10. Transcriptional Response to Sulfur Limitation in Pelagibacter ubique ArrayExpress

    ID: E-GEOD-31630

    Description: nfirmed S-adenosyl methionine (SAM) riboswitches: bhmT, mmuM, and metY. These genes were up to 33 times more abundant during low DMSP conditions and shunt all available sulfur to methionine. The osmotically inducible organic hydroperoxidase OsmC was the most up-regulated protein as DMSP (an osmolyte) became scarce. The second response, during sulfur-depleted stationary phase, saw increased transcription of the heme c shuttle ccmC and two small genes of unknown function (SAR11_1163 and SAR11_1164) which were 6-10 times higher in sulfur-starved cultures. No known membrane transporters were up-regulated in response to sulfur limitation, suggesting that this bacterium's strategy for coping with sulfur stress focuses on intracellularly redistributing, rather than importing, organic sulfur compounds. This supports the conclusion that the few organosulfur molecules that Ca. P. ubique is able to metabolize are rarely limiting in the marine environment....

  11. CCAAT/Enhancer Binding Proteins (C/EBP)-α and -β are Essential for Ovulation, Luteinization and the Expression of Key Target Genes ArrayExpress

    ID: E-GEOD-23084

    Description: ncluding effectors of vascular cell development. Bhmt, a gene controlling methionine metabolism and expressed exclusively in liver and kidney, was high in WT luteal cells but totally absent in Cebpa/b mutant cells. Because numerous genes potentially associated with vascular development were suppressed in the mutant cells, C/EBPa/b appear to dictate the luteinization process by also controlling genes that regulate the formation of the extensive vascular network required to sustain luteal cells. Thus, C/EBPa/b mediate several aspects of granulosa cell differentiation as well as the complex process of luteinization. Five granulosa cell treatments were included: CEBPα/β conditional KO ovary, eCG-treated 48h, hCG 4h wild type ovary, eCG-treated 48h, hCG 8h CEBPα/β conditional KO ovary, eCG-treated 48h, hCG 8h wild type ovary, eCG-treated 48h, hCG 24h CEBPα/β conditional KO ovary, eCG-treated 48h, hCG 24h...

  12. Transcriptional Response to Sulfur Limitation in Pelagibacter ubique BioProject

    ID: PRJNA145551

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nfirmed S-adenosyl methionine (SAM) riboswitches: bhmT, mmuM, and metY. These genes were up to 33 times more abundant during low DMSP conditions and shunt all available sulfur to methionine. The osmotically inducible organic hydroperoxidase OsmC was the most up-regulated protein as DMSP (an osmolyte) became scarce. The second response, during sulfur-depleted stationary phase, saw increased transcription of the heme c shuttle ccmC and two small genes of unknown function (SAR11_1163 and SAR11_1164) which were 6-10 times higher in sulfur-starved cultures. No known membrane transporters were up-regulated in response to sulfur limitation, suggesting that this bacterium's strategy for coping with sulfur stress focuses on intracellularly redistributing, rather than importing, organic sulfur compounds. This supports the conclusion that the few organosulfur molecules that Ca. P. ubique is able to metabolize are rarely limiting in the marine environment....
  13. Expression profiles dysplastic and neoplastic rat liver lesions BioProject

    ID: PRJNA132391

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: pressors Csmd1, Dmbt, Dusp1, and Gnmt ,in DN, and Bhmt, Dmbt1, Dusp1, Gadd45g, Gnmt, Napsa, Pp2ca, and Ptpn13, in HCC, was higher in BN than F344 rats. Comparative genomics approach, using gene expression data from rat lesions, and human HCC with different prognosis (based on survival length), revealed expression patterns of BN and F344 lesions close to those of human HCCs with better and poorer prognosis, respectively, suggesting that similar molecular events contribute to create a phenotype prone to progression in rats and human lesions. In conclusion, we identified a molecular signature of DN prone to progress to HCC and suggest that oncosuppressor genes are determinants of the genetically transmitted resistance to hepatocarcinogenesis. Overall design: Three-condition experiment, Normal liver vs. Dysplastic nodules and tumors. Biological replicates: 8 control replicates, 8 nodules replicates and 7 tumor replicates....
  14. CCAAT/Enhancer Binding Proteins (C/EBP)-α and -β are Essential for Ovulation, Luteinization and the Expression of Key Target Genes BioProject

    ID: PRJNA131671

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ncluding effectors of vascular cell development. Bhmt, a gene controlling methionine metabolism and expressed exclusively in liver and kidney, was high in WT luteal cells but totally absent in Cebpa/b mutant cells. Because numerous genes potentially associated with vascular development were suppressed in the mutant cells, C/EBPa/b appear to dictate the luteinization process by also controlling genes that regulate the formation of the extensive vascular network required to sustain luteal cells. Thus, C/EBPa/b mediate several aspects of granulosa cell differentiation as well as the complex process of luteinization. Overall design: Five granulosa cell treatments were included: CEBPα/β conditional KO ovary, eCG-treated 48h, hCG 4h wild type ovary, eCG-treated 48h, hCG 8h CEBPα/β conditional KO ovary, eCG-treated 48h, hCG 8h wild type ovary, eCG-treated 48h, hCG 24h CEBPα/β conditional KO ovary, eCG-treated 48h, hCG 24h...
  15. Expression profiles dysplastic and neoplastic rat liver lesions GEMMA

    ID: 1959

    Keywords: functional genomics

    Description: pressors Csmd1, Dmbt, Dusp1, and Gnmt ,in DN, and Bhmt, Dmbt1, Dusp1, Gadd45g, Gnmt, Napsa, Pp2ca, and Ptpn13, in HCC, was higher in BN than F344 rats. Comparative genomics approach, using gene expression data from rat lesions, and human HCC with different prognosis (based on survival length), revealed expression patterns of BN and F344 lesions close to those of human HCCs with better and poorer prognosis, respectively, suggesting that similar molecular events contribute to create a phenotype prone to progression in rats and human lesions. In conclusion, we identified a molecular signature of DN prone to progress to HCC and suggest that oncosuppressor genes are determinants of the genetically transmitted resistance to hepatocarcinogenesis. Last Updated (by provider): Oct 13 2010...

  16. Drug study: High-fat diet plus subchronic alcohol-induced effects in males of 14 inbred strains of mice MPD

    Data Type: strain

    Size: 14

    ID: MPD:430

    dimension.name: BHMT, protein expression relative to high-fat-only group

Displaying 16 of 16 results for "BHMT"