ATXN1 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 45 results for "ATXN1"
i
  1. Expression data from 6 day-old Atxn1L-/- and Atxn1-/- lung tissues BioProject

    ID: PRJNA141315

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Cerebellar RNA-Seq from ATXN1 Transgenic Mice Reveals SCA1 Disease Progression and Protection Pathways BioProject

    ID: PRJNA305316

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Expression data from 6 day-old Atxn1L-/- and Atxn1-/- lung tissues OmicsDI

    ID: E-GEOD-29551

    Date Released: 06-26-2012

    Description: gh expansion of a polyglutamine tract in ATAXIN1 (ATXN1) causes Spinocerebellar ataxia type 1, the functions of wild-type ATXN1 and ATAXIN1-Like (ATXN1L) remain poorly ...

  4. Expression data from 6 day-old Atxn1L-/- and Atxn1-/- lung tissues ArrayExpress

    ID: E-GEOD-29551

    Description: gh expansion of a polyglutamine tract in ATAXIN1 (ATXN1) causes Spinocerebellar ataxia type 1, the functions of wild-type ATXN1 and ATAXIN1-Like (ATXN1L) remain poorly ...

  5. Transcription profiling by array of cerebellum from ataxin1 knock-out mice OmicsDI

    ID: E-MEXP-886

    Date Released: 07-03-2014

    Description: Ataxin 1 (Atxn1) is a protein of unknown function associated with cerebellar neurodegeneration in spinocerebellar ataxia type 1 (SCA1). SCA1 ...

  6. Transcription profiling by array of cerebellum from ataxin1 knock-out mice ArrayExpress

    ID: E-MEXP-886

    Description: Ataxin 1 (Atxn1) is a protein of unknown function associated with cerebellar neurodegeneration in spinocerebellar ataxia type 1 (SCA1). SCA1 ...

  7. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans BioProject

    ID: PRJNA325369

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. HMGB1 contributes to mitochondrial DNA damage repair and extends lifespan in mutant ataxin-1 knock-in mice ArrayExpress

    ID: E-MTAB-2987

    Description: Mutant ataxin-1 (Atxn1), which causes spinocerebellar ataxia type 1 (SCA1), binds to and impairs the function of high mobility group box 1 (HMGB1), ...

  9. Capicua-dependent transcriptional changes in adult mouse cerebellum ArrayExpress

    ID: E-GEOD-32051

    Description: expansion of a translated CAG repeat in Ataxin-1 (ATXN1). The transcriptional repressor Cic binds directly to Atxn1 and plays a key role in SCA1 pathogenesis. Two isoforms of Cic, long (Cic-L) and short (Cic-S), are transcribed from alternative promoters. Using embryonic stem cells in which the Cic locus was targeted by an insertion of a genetra...

  10. HMGB1 contributes to mitochondrial DNA damage repair and extends lifespan in mutant ataxin-1 knock-in mice OmicsDI

    ID: E-MTAB-2987

    Date Released: 11-26-2014

    Description: Mutant ataxin-1 (Atxn1), which causes spinocerebellar ataxia type 1 (SCA1), binds to and impairs the function of high mobility group box 1 (HMGB1), ...

  11. Crystal Structure of AXH domain complexed with Capicua PDB

    ID: PDB:4J2L

    Description: Ataxin-1, Protein capicua homolog

    gene.name: ATXN1
  12. Capicua-dependent transcriptional changes in adult mouse cerebellum BioProject

    ID: PRJNA147673

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: expansion of a translated CAG repeat in Ataxin-1 (ATXN1). The transcriptional repressor Cic binds directly to Atxn1 and plays a key role in SCA1 pathogenesis. Two isoforms of Cic, long (Cic-L) and short (Cic-S), are transcribed from alternative promoters. Using embryonic stem cells in which the Cic locus was targeted by an insertion of a genetra...
  13. ATX1L_HUMAN UniProt:Swiss-Prot

    ID: P0C7T5

    Description: Ataxin-1-like AXH Interaction with NCOR2 and ATXN1 Self-association Pro-rich Phosphoserine Phosphothreonine Phosphoserine Phosphoserine In dbSNP:rs7194407....

  14. ATX1L_MOUSE UniProt:Swiss-Prot

    ID: P0C7T6

    Description: Ataxin-1-like AXH Interaction with NCOR2 and ATXN1 Self-association Phosphoserine Phosphothreonine Phosphoserine

  15. Capicua-dependent transcriptional changes in adult mouse cerebellum OmicsDI

    ID: E-GEOD-32051

    Date Released: 06-25-2012

    Description: expansion of a translated CAG repeat in Ataxin-1 (ATXN1). The transcriptional repressor Cic binds directly to Atxn1 and plays a key role in SCA1 pathogenesis. Two isoforms of Cic, long (Cic-L) and short (Cic-S), are transcribed from alternative promoters. Using embryonic stem cells in which the Cic locus was targeted by an insertion of a genetra...

  16. Gene expression profiling of B lymphocytes and plasma cells from Waldenstrons macroglobulinemia ArrayExpress

    ID: E-GEOD-6691

    Description: WM and CLL: LEF1 (WNT/├čcatenin pathway), MARCKS, ATXN1 and FMOD. We also found deregulation of genes involved in plasma cell differentiation such as PAX5 which was overexpressed in WM-PC, and IRF4 and BLIMP1 which were underexpressed. In addition, three of the target genes activated by PAX5 -CD79, BLNK and SYK- were up-regulated in WM-PC. In summary, these results indicate that both PC and BL from WM are genetically different from the MM and CLL cell-counterpart. Keywords: Waldenstrons macroglobulinemia, expression profiling, microarrays, Affymetrix. Bone marrow (BM) samples from 10 patients with Waldenstrons macroglobulinemia (WM), 12 with multiple myeloma (MM) and 11 with chronic lymphocytic leukemia (CLL) were included in the study. All samples corresponded to newly diagnosed untreated patients. In addition, 8 normal B lymphocytes samples (NBL) from peripheral blood and 5 normal plasma cells (NPC) from bone marrow of healthy donors were also selected in order to relate the deregulation...

  17. Quantitative interaction proteomics of neurodegenerative disease proteins. OmicsDI

    ID: GPM32320018141

    Date Released:

    Description: in (PARK2) for Parkinson"s disease, and Ataxin-1 (ATXN1) for spinocerebellar ataxia type 1 ... {{/i}}...

  18. Transcription profiling by array of the response of Saccharomyces cerevisiae ATX1 knockouts under copper deficient and high copper conditions ArrayExpress

    ID: E-MTAB-4230

    Description: In this study, genome-wide effect of the absence of ATX1 gene was investigated under copper deficient and high copper (0.5 mM) conditions in comparsio...

  19. COPPER CHAPERONE ATX1 FROM SYNECHOCYSTIS PCC6803 (CU1 FORM) PDB

    ID: PDB:2XMT

    Description: SSR2857 PROTEIN

  20. Crystal structure of AXH domain complex with Capicua PDB

    ID: PDB:4J2J

    Description: Ataxin-1, Protein capicua homolog

    gene.name: ATXN1

Displaying 20 of 45 results for "ATXN1"