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  1. Proteomic analysis of the rat canalicular membrane reveals expression of a complex system of P4-ATPases in liver OmicsDI

    ID: PXD003299

    Date Released: 07-05-2016

    Description: four more P4-ATPases were identified. ATP8A1 and ATP9A shows expression specific to the canalicular membrane, ATP11C in the basolateral membrane and adjacent intracellular vesicles and ATP11A in an intracellular vesicular compartment partially colocalizing with RAB7A. This study helped to identify additional P4-ATPases from rat liver particularly in the canalicular membrane, previously not known to express in liver. These identified ATPases might be involved in transmembrane lipid homeostasis. The two newly identified P4-ATPases in the canalicular membrane may protect the canalicular membrane from the detergent action of bile salts....


Displaying 1 of 1 results for "ATP9A"