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Displaying 20 of 399 results for "ATG5"
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  1. microRNA profiling by array of Atg5 knock out mouse embryonic fibroblasts following EBSS induced autophagy ArrayExpress

    ID: E-MTAB-880

    Description: ression of 6h EBSS treatment induced autophagy in Atg5 WT and KO mouse embryonic fibroblasts (MEF) were examined. For the 1st comparison, the control group is Atg5 WT MEF ...

  2. microRNA profiling by array of Atg5 knock out mouse embryonic fibroblasts following EBSS induced autophagy OmicsDI

    ID: E-MTAB-880

    Date Released: 05-02-2014

    Description: ression of 6h EBSS treatment induced autophagy in Atg5 WT and KO mouse embryonic fibroblasts (MEF) were examined. For the 1st comparison, the control group is Atg5 WT MEF ...

  3. Autophagy and alternative NF-kappaB inhibition by RNAi against RELB, ATG5 or ULK1 in A549 human cancer cells BioProject

    ID: PRJNA296066

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Autophagy and alternative NF-kappaB inhibition by RNAi against RELB, ATG5 or ULK1 in A549 human cancer cells OmicsDI

    ID: E-GEOD-73158

    Date Released: 09-26-2015

    Description: knockdown the expression of core autophagy genes (ATG5, ULK1) or the key subunit of alternative NF-kappaB RELB. Seven samples were prepared for each biological replicate; two sequence independent non-targeting control siRNAs were transfected as a negative control. Three sequence independent siRNAs targeting the core autophagy machinery wer...

  5. Expression in IFN-gamma treated control and Atg5-/- macrophages ArrayExpress

    ID: E-GEOD-34863

    Description: viral infection. We report a requirement for the Atg5-Atg12/Atg16L1 autophagosome elongation complex in IFNγ-mediated control of murine norovirus in macrophages. We use microarrays to compare transcriptional changes induced in control and Atg5 deficient macrophages by IFNγ treatment. Bone marrow derived macrophages were gen...

  6. Global analysis of impact of Atg5 mutation on steady-state protein levels OmicsDI

    ID: PXD003558

    Date Released: 06-14-2016

    Description: This experiment analyzes the global impact of Atg5-/- mutation on steady-state protein levels by a standard SILAC experiment. WT+vector cells were grown in isotopically labeled ...

  7. Expression in IFN-gamma treated control and Atg5-/- macrophages BioProject

    ID: PRJNA150127

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Identification Atg5-related microRNAs involved in the regulation of tumor formation BioProject

    ID: PRJNA169401

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. Identification Atg5-related microRNAs involved in the regulation of tumor formation ArrayExpress

    ID: E-GEOD-38911

    Description: ogene was introduced into mouse embryo fibroblast Atg5 wild type [MEF-Atg5(+/+)] and Atg5 knock-out [MEF-Atg5(-/-)] cells and the stable cell lines MR and M5R were established, respectively. Our results showed that M5R cell induced larger tumor formation compared with MR cells while these two cell lines were subcutaneously injected into SCID mice under Ha-ras overexpression conditions. It ...

  10. Autophagy and alternative NF-kappaB inhibition by RNAi against RELB, ATG5 or ULK1 in A549 human cancer cells ArrayExpress

    ID: E-GEOD-73158

    Description: knockdown the expression of core autophagy genes (ATG5, ULK1) or the key subunit of alternative NF-kappaB RELB. Seven samples were prepared for each biological replicate; two sequence independent non-targeting control siRNAs were transfected as a negative control. Three sequence independent siRNAs targeting the core autophagy machinery wer...

  11. Identification Atg5-related microRNAs involved in the regulation of tumor formation OmicsDI

    ID: E-GEOD-38911

    Date Released: 07-17-2012

    Description: ogene was introduced into mouse embryo fibroblast Atg5 wild type [MEF-Atg5(+/+)] and Atg5 knock-out [MEF-Atg5(-/-)] cells and the stable cell lines MR and M5R were established, respectively. Our results showed that M5R cell induced larger tumor formation compared with MR cells while these two cell lines were subcutaneously injected into SCID mice under Ha-ras overexpression conditions. It ...

  12. Transcription profiling of mouse colonic goblet cells deficient in Atg5 ArrayExpress

    ID: E-TABM-815

    Description: t into the transcriptional changes resulting from Atg5 deficiency in colonic goblet cells....

  13. Expression in IFN-gamma treated control and Atg5-/- macrophages OmicsDI

    ID: E-GEOD-34863

    Date Released: 01-16-2012

    Description: viral infection. We report a requirement for the Atg5-Atg12/Atg16L1 autophagosome elongation complex in IFNγ-mediated control of murine norovirus in macrophages. We use microarrays to compare transcriptional changes induced in control and Atg5 deficient macrophages by IFNγ treatment. Bone marrow derived macrophages were gen...

  14. Global analysis of protein degradation rates in wildtype, Atg5-/- and Atg7-/- primary human fibroblasts OmicsDI

    ID: PXD003562

    Date Released: 06-14-2016

    Description: n rates between wildtype and autophagy deficient (Atg5-/- and Atg7-/-) cells. The media utilized for isotopic labeling was Eagle’s Minimum Essential Medium (ATCC) supplemented with 15% dialyzed fetal bovine serum (Thermo Scientific), 100U/mL penicillin, 100U/mL streptomycin. Prior to labeling, cells were gradually adapted to unlabeled media over the course of multiple passages. Cells were then plat...

  15. Transcription profiling of mouse colonic goblet cells deficient in Atg5 OmicsDI

    ID: E-TABM-815

    Date Released: 05-02-2014

    Description: t into the transcriptional changes resulting from Atg5 deficiency in colonic goblet cells....

  16. Impact of conditional autophagy knockout on cytotoxic CD8 T cells at day 7 and day 8 after influenza infection OmicsDI

    ID: E-GEOD-49254

    Date Released: 04-27-2015

    Description: cells, we developed a new mouse that expresses an Atg5 gene with loxP sites up- and downstream of the exon 3, Cre-recombinase, T cell receptor specific for the OVA peptide SIINFEKL and the congenic marker Thy1.1. These cells were adoptiv...

  17. Impact of conditional autophagy knockout on cytotoxic CD8 T cells at day 7 and day 8 after influenza infection ArrayExpress

    ID: E-GEOD-49254

    Description: cells, we developed a new mouse that expresses an Atg5 gene with loxP sites up- and downstream of the exon 3, Cre-recombinase, T cell receptor specific for the OVA peptide SIINFEKL and the congenic marker Thy1.1. These cells were adoptiv...

  18. Wild type and ATG5-KO mouse dendritic cells exposed to interleukin-4 (IL4) and/or lipopolisaccharyde (LPS) BioProject

    ID: PRJNA244977

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. Wild type and ATG5-KO mouse dendritic cells exposed to interleukin-4 (IL4) and/or lipopolisaccharyde (LPS) OmicsDI

    ID: E-GEOD-56929

    Date Released: 06-21-2015

    Description: Male C57BL/6 normal and ATG5-KO mouse dendritic cells exposed to interleukin-4 (IL4) and/or lipopolisaccharyde (LPS) 24 samples representing the different ...

  20. Crystal structure of Kluyveromyces marxianus Atg5 PDB

    ID: PDB:3VQI

    Description: Atg5


Displaying 20 of 399 results for "ATG5"