ATF3 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 396 results for "ATF3"
i
  1. Loss of Activating Transcription Factor 3 reveals a distinct gene expression program modulating cell organization during pancreatitis. BioProject

    ID: PRJNA257817

    Keywords: Epigenomics

    Access Type: download

  2. Activating transcription factor 3 regulates immune and metabolic homeostasis BioProject

    ID: PRJNA153257

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. ChIP-chip from HCT116 cells treated with MMS and LNCaP cells with ATF3 BioProject

    ID: PRJNA118175

    Keywords: Other

    Access Type: download

  4. ATF3 is a novel regulator of mouse neutrophil migration. BioProject

    ID: PRJNA234095

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. ATF3 is a novel regulator of mouse neutrophil migration. OmicsDI

    ID: E-GEOD-53973

    Date Released: 06-03-2014

    Description: Expression of the activating transcription factor 3 (ATF3) gene is induce...

  6. Activating transcription factor 3 regulates immune and metabolic homeostasis ArrayExpress

    ID: E-GEOD-36377

    Description: phila basic region-leucine zipper (bZIP) protein, Activating transcription factor 3 (Atf3), safeguards a balance of metabolic and immune system responses during fly development. Loss of Atf3 function results in lethality during late-larval and pupal stages. Atf3-deficient larvae exhibit phenotypes resembling the metabolic syndrome in mammals. Excessive accumulation of lipids in the larval fat body and gut is accompanied by altered expression of genes involved in lipid metabolism. More...

  7. ATF3 is a novel regulator of mouse neutrophil migration ArrayExpress

    ID: E-GEOD-53973

    Description: Expression of the activating transcription factor 3 (ATF3) gene is induce...

  8. Loss of Activating Transcription Factor 3 reveals a distinct gene expression program modulating cell organization during pancreatitis ArrayExpress

    ID: E-GEOD-60250

    Description: his phenomenon. Here, we define a novel role for Activating Transcription Factor 3 (ATF3) during pancreatic injury. ATF3, a key mediator in the unfolded protein response, is robustly expressed in acinar cells during pancreatitis. Targeted deletion of Atf3 altered the molecular response to injury, with Atf3-/- acinar cells maintaining cell o...

  9. ChIP-chip from HCT116 cells treated with MMS and LNCaP cells with ATF3 ArrayExpress

    ID: E-GEOD-18457

    Description: grity is essential for survival of all organisms. Activating transcription factor 3 (ATF3) is a member of the c-AMP response element...

  10. Activating transcription factor 3 regulates immune and metabolic homeostasis OmicsDI

    ID: E-GEOD-36377

    Date Released: 03-11-2013

    Description: phila basic region-leucine zipper (bZIP) protein, Activating transcription factor 3 (Atf3), safeguards a balance of metabolic and immune system responses during fly development. Loss of Atf3 function results in lethality during late-larval and pupal stages. Atf3-deficient larvae exhibit phenotypes resembling the metabolic syndrome in mammals. Excessive accumulation of lipids in the larval fat body and gut is accompanied by altered expression of genes involved in lipid metabolism. More...

  11. ChIP-chip from HCT116 cells treated with MMS and LNCaP cells with ATF3 OmicsDI

    ID: E-GEOD-18457

    Date Released: 05-01-2014

    Description: grity is essential for survival of all organisms. Activating transcription factor 3 (ATF3) is a member of the c-AMP response element...

  12. Loss of Activating Transcription Factor 3 reveals a distinct gene expression program modulating cell organization during pancreatitis. OmicsDI

    ID: E-GEOD-60250

    Date Released: 08-19-2015

    Description: his phenomenon. Here, we define a novel role for Activating Transcription Factor 3 (ATF3) during pancreatic injury. ATF3, a key mediator in the unfolded protein response, is robustly expressed in acinar cells during pancreatitis. Targeted deletion of Atf3 altered the molecular response to injury, with Atf3-/- acinar cells maintaining cell o...

  13. The anti-inflammatory nature of HDL in macrophages is mediated by ATF3 BioProject

    ID: PRJNA188404

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. The Common Stress Responsive Transcription Factor ATF3 Binds Active Enhancers and Bookmarks Genomic Sites for Transcriptional Regulation [array] BioProject

    ID: PRJNA299822

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. The Common Stress Responsive Transcription Factor ATF3 Binds Active Enhancers and Bookmarks Genomic Sites for Transcriptional Regulation [ChIP-seq] BioProject

    ID: PRJNA299821

    Keywords: Epigenomics

    Access Type: download

  16. The anti-inflammatory nature of HDL in macrophages is mediated by ATF3 ArrayExpress

    ID: E-GEOD-44034

    Description: normocholesteremic conditions by suppressing the transcription of inflammatory cytokines in a manner independent of its ability to remove cellular cholesterol. We identify Activating Transcription Factor 3 (ATF3), a transcriptional repressor of the CREB family of basic leucine zipper transcription factors, as a HDL-inducible regulator of macrophage activation. HDL’s ability to down modulate TLR responses was severely compromised in ATF3-deficient cells demonstrating that ATF3 mediates HDL's anti-inflammatory effects and may explain the broad anti-inflammatory functions of HDL. Bone marrow-derived macrophages (BMDMs) were obtained by culturing bone marrow cells from 6 to 8 week old wildtype C57BL/6 mice in DMEM supplemented with 10% FCS, 10 mg ml-1 Ciprobay-500 and 40 ng ml-1 M-CSF (R & D Systems). BMDMs of wt mice were pretreated for 6 h with HDL (2 mg ml-1 ) then stimulated with CpG (100 nM) for 4 h. Further wild type or Atf3-deficient BMDMs were pretreated with 2 mg ml-1 HDL for 6 h and subsequently stimulated with CpG (100 nM) or P3C (50 ng ml-1) for 4 h. For carotid artery injury approximately 12-wee...

  17. ATF3 links host adaptive-response to breast cancer metastasis BioProject

    ID: PRJNA157027

    Keywords: Transcriptome or Gene expression

    Access Type: download

  18. ATF3 links host adaptive-response to breast cancer metastasis OmicsDI

    ID: E-GEOD-36904

    Date Released: 06-02-2014

    Description: ortant role in cancer development. We identified ATF3, an adaptive-response gene, in the host to facilitate metastasis. We also demonstrated that the macrophage is one of the key cell types for host-ATF3

  19. The Response of the Prostate to Changes in Circulating Cholesterol: Activating Transcription Factor 3 (ATF3) as a Cholesterol Sensor OmicsDI

    ID: E-GEOD-25500

    Date Released: 12-13-2011

    Description: This SuperSeries is composed of the following subset Series: GSE25461: Gene expression of three prostate lobes, ventral prostate (VP), dorsal lateral ...

  20. Alterations in Neuronal Gene Expression Profiles in Response to Experimental Demyelination and Axonal Transection BioProject

    ID: PRJNA113555

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: elination conditions. The increased expression of activating transcription factor 3 (Atf3) and thyrotropin-releasing hormone (Trh) in both injury paradigms was validated by immunohistochemistry. Expression of Atf3 in a patient with Marburg’s variant of multiple sclerosis was also detected in the pons with large cerebellar demyelination, confirming the activation of the Atf3 pathway in a human disease sample as well. This experimental approach may be useful for the identification of pathways that could be targeted for remyelinative and neuroprotective drug development. Overall design: The pontine nuclei containing the neuronal cell bodies of the projecting lesioned axons (saline, lysolecithin or transection) were collected at different time points post-intervention (day 4, day 10, and day 37), and assayed for changes in gene expression caused by the...

Displaying 20 of 396 results for "ATF3"