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Displaying 20 of 702 results for "ASL"
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  1. Crystal Structure of the Human Argininosuccinate Lyase Q286R Mutant PDB

    ID: PDB:1K62

    Description: Argininosuccinate Lyase (E.C.4.3.2.1)

  2. HUMAN ARGININOSUCCINATE LYASE PDB

    ID: PDB:1AOS

    Description: ARGININOSUCCINATE LYASE

  3. Crystal Structure of T.th.HB8 Argininosuccinate lyase complexed with L-Arginine PDB

    ID: PDB:2E9F

    Description: Argininosuccinate lyase (E.C.4.3.2.1)

  4. Structure determination and refinement at 2.44 A resolution of Argininosuccinate lyase from E. coli PDB

    ID: PDB:1TJ7

    Description: Argininosuccinate lyase (E.C.4.3.2.1)

  5. ARLY_BOVIN UniProt:Swiss-Prot

    ID: Q3SZJ0

    Description: Removed Argininosuccinate lyase N-acetylalanine N6-acetyllysine N6-acetyllysine N6-acetyllysine

  6. ARLY_ANSAN UniProt:Swiss-Prot

    ID: P33110

    Description: Argininosuccinate lyase Substrate binding Proton acceptor; shared with tetrameric partner 2 Proton acceptor; sha...

  7. Gene expression profile of trachea primary airway epithelial cultures from newborn CFTR knockout pigs OmicsDI

    ID: E-GEOD-36906

    Date Released: 09-25-2015

    Description: pe pigs, the thin layer of airway surface liquid (ASL) rapidly killed bacteria in vivo, when removed from the lung, and in primary epithelial cultures. Lack of CFTR reduced bacterial killing. We found that ASL pH was more acidic in CF, and reducing pH inhibited the antimicrobial activity of ASL. Reducing ASL pH diminished bacterial killing in wild-type pigs, and increasing ASL pH rescued killing in CF pigs. These results directly link the initial host defense defect to loss of CFTR, an anion channel that facilitates HCO3- transport. Without CFTR, airway epithelial HCO3- secretion is defective, ASL pH falls and inhibits antimicrobial function, and thereby impairs killing of bacteria that enter the newborn lung. These findings suggest that increasing ASL pH might prevent the initial infection in patients with CF and that assaying ASL pH or bacterial killing cou...

  8. Solution structure of the tRNA-Arg2 (ICG) ASL. PDB

    ID: PDB:2KRQ

    Description: 5'-R(*CP*UP*CP*GP*GP*CP*UP*IP*CP*GP*AP*AP*CP*CP*GP*AP*G)-3'

  9. ASL data demonstrating gam denoising Figshare

    ID: doi:10.6084/M9.FIGSHARE.1409657.V1

    Release Date: 01-19-2016

    Description:

  10. Gene expression profile of trachea primary airway epithelial cultures from newborn CFTR knockout pigs ArrayExpress

    ID: E-GEOD-36906

    Description: pe pigs, the thin layer of airway surface liquid (ASL) rapidly killed bacteria in vivo, when removed from the lung, and in primary epithelial cultures. Lack of CFTR reduced bacterial killing. We found that ASL pH was more acidic in CF, and reducing pH inhibited the antimicrobial activity of ASL. Reducing ASL pH diminished bacterial killing in wild-type pigs, and increasing ASL pH rescued killing in CF pigs. These results directly link the initial host defense defect to loss of CFTR, an anion channel that facilitates HCO3- transport. Without CFTR, airway epithelial HCO3- secretion is defective, ASL pH falls and inhibits antimicrobial function, and thereby impairs killing of bacteria that enter the newborn lung. These findings suggest that increasing ASL pH might prevent the initial infection in patients with CF and that assaying ASL pH or bacterial killing cou...

  11. ARLY_LITCT UniProt:Swiss-Prot

    ID: P51464

    Description: Argininosuccinate lyase

  12. ASL data demonstrating gam denoising Figshare

    ID: doi:10.6084/M9.FIGSHARE.1409657

    Release Date: 05-11-2015

    Description:

  13. Reduced Airway Surface pH Impairs Bacterial Killing in the Porcine Cystic Fibrosis Lung BioProject

    ID: PRJNA157321

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: pe pigs, the thin layer of airway surface liquid (ASL) rapidly killed bacteria in vivo, when removed from the lung, and in primary epithelial cultures. Lack of CFTR reduced bacterial killing. We found that ASL pH was more acidic in CF, and reducing pH inhibited the antimicrobial activity of ASL. Reducing ASL pH diminished bacterial killing in wild-type pigs, and increasing ASL pH rescued killing in CF pigs. These results directly link the initial host defense defect to loss of CFTR, an anion channel that facilitates HCO3- transport. Without CFTR, airway epithelial HCO3- secretion is defective, ASL pH falls and inhibits antimicrobial function, and thereby impairs killing of bacteria that enter the newborn lung. These findings suggest that increasing ASL pH might prevent the initial infection in patients with CF and that assaying ASL pH or bacterial killing cou...
  14. Solution structure of the human mitochondrial tRNAMet ASL containing the 5-formylcytidine modification in position 34 PDB

    ID: PDB:2KRY

    Description: 5'-R(*(PSU)P*CP*GP*GP*GP*CP*CP*(RSQ)P*AP*UP*AP*CP*CP*CP*CP*GP*A)-3'

  15. CCDC 1478452: Experimental Crystal Structure Determination CCDC

    ID: doi:10.5517/CCDC.CSD.CC1LMG0P

    Release Date: 10-20-2016

    dataset.creators: Asl, HoomanYaghoobnejad
  16. Solution structure of the E. coli tRNA-Arg1 (ICG) ASL containing the 2-thiocytidine modification PDB

    ID: PDB:2KRV

    Description: 5'-R(*CP*UP*CP*GP*GP*(RSP)P*UP*IP*CP*GP*AP*AP*CP*CP*GP*AP*G)-3'

  17. Functional MRI data in MATLAB file format for ASL from How the heart speaks to the brain: neural activity during cardiorespiratory interoceptive stimulation... Figshare

    ID: doi:10.6084/M9.FIGSHARE.3843327

    Release Date: 09-21-2016

    Description: 1 to 3 are contrast maps built by subtracting the ASL signal averaged over the baseline block (as defined in the text) from the ASL signal averaged across anticipatory, peak and recovery blocks, respectively (as defined in the text). The contrast maps have 5 dimensions and include data for 21 subjects (second ...

  18. CCDC 1478454: Experimental Crystal Structure Determination CCDC

    ID: doi:10.5517/CCDC.CSD.CC1LMG2R

    Release Date: 10-20-2016

    dataset.creators: Asl, HoomanYaghoobnejad
  19. Data from: Assortative social learning and its implications for human (and animal?) societies Dryad

    DateIssued: 07-02-2014

    Description: udy the evolution of assortative social learning (ASL), where assorting on a trait acts as an individual-specific mechanism for filtering relevant models from which to learn when that trait varies. We show that when the trait is polymorphic, ASL may maintain a stable behavioral polymorphism within a population (independently of coexistence with individual learning in a population). We explore the evolution of ASL when assortment is based on a nonheritable or partially heritable trait, and when ASL competes with different non-ASL strategies: oblique (learnin...

  20. CCDC 1478453: Experimental Crystal Structure Determination CCDC

    ID: doi:10.5517/CCDC.CSD.CC1LMG1Q

    Release Date: 10-20-2016

    dataset.creators: Asl, HoomanYaghoobnejad

Displaying 20 of 702 results for "ASL"