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Displaying 20 of 163 results for "ARNTL"
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  1. CLOCK_MOUSE UniProt:Swiss-Prot

    ID: O08785

    Description: crease in transcriptional activation by the CLOCK-ARNTL/BMAL1 heterodimer. Significant decrease in transcriptional activation by the CLOCK-ARNTL/BMAL1 heterodimer, reduced nuclear localization and DNA-binding; when associated with D-42 Significant decrease in transcriptional activation by the CLOCK-ARNTL/BMAL1 heterodimer. Significant decrease in transcriptional activation by the CLOCK-ARNTL/BMAL1 heterodimer, reduced nuclear localization and DNA-binding; when associated with D-38 Reduced ARNTL/BMAL1 binding. Abolishes transcriptional activation by the CLOCK-ARNTL/BMAL1 heterodimer. Abolishes regulation of circad...

  2. Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex PDB

    ID: PDB:4F3L

    Description: BMAL1b, Circadian locomoter output cycles protein kaput (E.C.2.3.1.48)

    gene.name: Arntl, BMAL1, bmal1b
  3. Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA PDB

    ID: PDB:4H10

    Description: Aryl hydrocarbon receptor nuclear translocator-like protein 1, Circadian locomoter output cycles protein kaput (E.C.2.3.1.48)/DNA complex

    gene.name: ARNTL, BHLHE5, BMAL1, MOP3, PASD3
  4. BHE40_PONAB UniProt:Swiss-Prot

    ID: Q5RAI7

    Description: ein 40 bHLH Orange Essential for interaction with ARNTL/BMAL1, E-box binding and repressor activity against the CLOCK-ARNTL/BMAL1 heterodimer Necessary for interaction with RXRA and repressor activ...

  5. BHE40_RAT UniProt:Swiss-Prot

    ID: O35780

    Description: ein 40 bHLH Orange Essential for interaction with ARNTL/BMAL1, E-box binding and repressor activity against the CLOCK-ARNTL/BMAL1 heterodimer Necessary for interaction with RXRA and repressor activ...

  6. CRY1_MOUSE UniProt:Swiss-Prot

    ID: P97784

    Description: e alpha/beta FAD Required for inhibition of CLOCK-ARNTL/BMAL1-mediated transcription Interaction with TIMELESS FAD; via amide nitrogen FAD FAD Phosphoserine; by AMPK Phosphoserine; by MAPK Phosphoserine; by AMPK Phosph...

  7. BHE40_SHEEP UniProt:Swiss-Prot

    ID: B3F209

    Description: ein 40 bHLH Orange Essential for interaction with ARNTL/BMAL1, E-box binding and repressor activity against the CLOCK-ARNTL/BMAL1 heterodimer Necessary for interaction with RXRA and repressor activ...

  8. Targeted deletion of circadian clock gene Arntl in the nephron results in dysregulation of diverse metabolic pathways ArrayExpress

    ID: E-GEOD-76838

    Description: disposition. Mice with a specific ablation of the Arntl gene encoding BMAL1 in the renal tubular cells were compared to wild-type littermate at ZT4 and ZT16 (ZT – Zeitgeber time units; ZT0 is the time of light on and ZT12 is the time of light off)....

  9. Targeted deletion of circadian clock gene Arntl in the nephron results in dysregulation of diverse metabolic pathways BioProject

    ID: PRJNA308742

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. BHE40_BOVIN UniProt:Swiss-Prot

    ID: Q5EA15

    Description: ein 40 bHLH Orange Essential for interaction with ARNTL/BMAL1, E-box binding and repressor activity against the CLOCK-ARNTL/BMAL1 heterodimer Necessary for interaction with RXRA and repressor activ...

  11. Mus musculus : Transcriptome of mouse liver in WT and Bmal1 KO mice BioProject

    ID: PRJDB2026

    Keywords: Other

    Access Type: download

  12. ChIP-seq of circadian transcription factors in MLL-AF9 leukemia cell lines ArrayExpress

    ID: E-GEOD-70686

    Description: he core circadian transcription factors CLOCK and ARNTL (BMAL1) in NOMO-1 and THP-1 cells....

  13. ChIP-seq of circadian transcription factors in MLL-AF9 leukemia cell lines BioProject

    ID: PRJNA289353

    Keywords: Epigenomics

    Access Type: download

    dataset.description: he core circadian transcription factors CLOCK and ARNTL (BMAL1) in NOMO-1 and THP-1 cells....
  14. Targeted deletion of circadian clock gene Arntl in the nephron results in dysregulation of diverse metabolic pathways OmicsDI

    ID: E-GEOD-76838

    Date Released: 06-04-2016

    Description: disposition. Mice with a specific ablation of the Arntl gene encoding BMAL1 in the renal tubular cells were compared to wild-type littermate at ZT4 and ZT16 (ZT – Zeitgeber time units; ZT0 is the time of light on and ZT12 is the time of light off)....

  15. Characterisation of Two New Th17-Subsets with Distinct Contribution to HIV-1 Persistence under Antiretroviral Therapy BioProject

    ID: PRJNA278524

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: al Th17 transcripts (e.g., RORγt, RORα, PTPN13, ARNTL), C. albicans specificity, and exhibiting Th17-lineage commitment versus flexibility. Overall design: 4 cell populations from up to 6 donors for a total of 20 samples....
  16. Characterisation of Two New Th17-Subsets with Distinct Contribution to HIV-1 Persistence under Antiretroviral Therapy ArrayExpress

    ID: E-GEOD-66972

    Description: al Th17 transcripts (e.g., RORγt, RORα, PTPN13, ARNTL), C. albicans specificity, and exhibiting Th17-lineage commitment versus flexibility. 4 cell populations from up to 6 donors for a total of 20 samples....

  17. Sex-related differences in gene expression following Coxiella burnetii infection: potential role of circadian rhythm ArrayExpress

    ID: E-GEOD-21065

    Description: hythm pathway, which consists of positive (Clock, Arntl) and negative (Per) limbs of a feedback loop. We found that Clock and Arntl were down-modulated whereas Per was up-regulated; these changes may be associated with efficient bacterial elimination in females but not in males, in which an exacerbated host response would be prominent. This large-scale study revealed for the first time that circadian rhythm plays a major role in the anti-infectious response of mice, and it provides a new basis for elucidating the role of sexual dimorphism in human infections. Liver transcriptome was analyzed using whole genome microarray. Forty mice were divided into 8 groups of five mice upon three binary factors: sex, infection and castration. Four Samples were excluded from final analysis (see Data Processing for additional details)....

  18. ECSTASY (MDMA) ALTERS CARDIAC GENE EXPRESSION AND DNA METHYLATION: IMPLICATIONS FOR CIRCADIAN RHYTHM DYSFUNCTION IN THE HEART (methylation) ArrayExpress

    ID: E-GEOD-68199

    Description: After 35d, circadian rhythm genes (Per3, CLOCK, ARNTL, and NPAS2) remained differentially expressed. MDMA caused DNA hypermethylation and hypomethylation that was independent of gene expression; hypermethylation of genes was 71% at 10d, 68% at 35d, and 91% at 10+25d. Differential gene expression that corresponded directly with DNA methylation changes occurred in 22% of genes at 10d, 17% at 35d, and 48% at 10d+25d washout. MDMA treatment resulted in epigenetic changes in cardiac DNA methylation. Hypermethylation was the predominant effect. MDMA induced gene expression of key elements of circadian rhythm regulatory genes and suggest a fundamental mechanism for MDMA dysfunction in the heart. This study addresses how MDMA (ecstasy) affects cardiac (left ventricle) gene expression and epigenetic nuclear DNA methylation. Each sample was fluorescently labeled and hybridized to Roche Nimblegen 2.1M Deluxe Promoter Arrays....

  19. CRY1_SPAJD UniProt:Swiss-Prot

    ID: Q70AD6

    Description: e alpha/beta FAD Required for inhibition of CLOCK-ARNTL/BMAL1-mediated transcription Interaction with TIMELESS FAD; via amide nitrogen FAD FAD Phosphoserine; by AMPK Phosphoserine; by MAPK Phosphoserine; by AMPK Phosph...

  20. CLK:BMAL1 is a pioneer-like transcription factor ArrayExpress

    ID: E-GEOD-47145

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series


Displaying 20 of 163 results for "ARNTL"