ARHGEF11 | bioCADDIE Data Discovery Index
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Displaying 16 of 16 results for "ARHGEF11"
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  1. PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex PDB

    ID: PDB:5E6P

    Description: Plexin-B2, Rho guanine nucleotide exchange factor 11

  2. Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide PDB

    ID: PDB:5TYT

    Description: Rho guanine nucleotide exchange factor 11

  3. Solution structure of the PDZ domain of human Rho guanine nucleotide exchange factor 11 PDB

    ID: PDB:2DLS

    Description: Rho guanine nucleotide exchange factor 11

  4. STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF PDB

    ID: PDB:1HTJ

    Description: KIAA0380

  5. Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA PDB

    ID: PDB:3KZ1

    Description: Rho guanine nucleotide exchange factor 11

  6. Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11 PDB

    ID: PDB:5JHG

    Description: Rho guanine nucleotide exchange factor 11

  7. Crystal structure of the ternary complex between the human RhoA, its inhibitor and the DH/PH domain of human ARHGEF11 PDB

    ID: PDB:5JHH

    Description: Rho guanine nucleotide exchange factor 11

  8. Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF PDB

    ID: PDB:1XCG

    Description: Rho guanine nucleotide exchange factor 11

  9. Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA PDB

    ID: PDB:3T06

    Description: Rho guanine nucleotide exchange factor 11

  10. Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GDP PDB

    ID: PDB:3CX6

    Description: Guanine nucleotide-binding protein alpha-13 subunit, Rho guanine

  11. Crystal Structure of PDZRhoGEF rgRGS Domain in a Complex with Galpha-13 Bound to GTP-gamma-S PDB

    ID: PDB:3CX8

    Description: Guanine nucleotide-binding protein alpha-13 subunit, Rho guanine

  12. ARHGB_RAT UniProt:Swiss-Prot

    ID: Q9ES67

    Description: Rho guanine nucleotide exchange factor 11

  13. A whole genome map of alternative splicing events in precancerous lung dysplasia and adenocarcinomas of c-Raf mice ArrayExpress

    ID: E-GEOD-38948

    Description: script and protein level agreed well, whereas for Arhgef11, Clstn1, Dlg1, Dock9, Mbnl2, Mfge8, Npnt, Pdlim5, Ppp2r5c, Tjp1 notable differences in the abundance of variant transcripts were observed by RT-PCR and gel electrophoresis. Moreover, expression of individual variants differed between dysplasia and carcinoma to suggest their disease dependent regulation. Western blotting of IQGAP1, MYO6, PTPRM, RABGAP1L and RAD50 confirmed significant regulation of isoforms in lung cancer as compared to non-transgenic, transgenic unaltered and dysplastic lung tissue. For 46 AS genes expression of the non-variant protein was reported in human lung cancer (www.proteinatlas.org) and for 13 of these, cancer related AS events are known. Overall, new insight into lung dysplasia was obtained with 43 new cancer related AS genes to aid diagnosis and molecular intervention strategies. We analyzed and compared dysplastic (n=4) and adenocarcinoma (n=4) lesions and with transgenic but unaltered (n=4) and non-transgenic (n=5) lung tissue obtained from SPC/c-Raf transgenic mice with aid of laser micro dissection pressure catapulted (LMPC) technique. Dysplasia is a pre-neoplastic condition and developed at 5 month of age in the proposed mouse model. LMPC provides precise microscopic lesion collection without contamination. The RNA samples were analyzed using the Affymetrix Mouse Exon 1.0 ST platform. Alternative splicing was analyzed using ...

  14. Solution structure of the PDZ domain (3614- 3713 ) from human obscurin PDB

    ID: PDB:2EDH

    Description: Obscurin

  15. A whole genome map of alternative splicing events in precancerous lung dysplasia and adenocarcinomas of c-Raf mice BioProject

    ID: PRJNA169356

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: script and protein level agreed well, whereas for Arhgef11, Clstn1, Dlg1, Dock9, Mbnl2, Mfge8, Npnt, Pdlim5, Ppp2r5c, Tjp1 notable differences in the abundance of variant transcripts were observed by RT-PCR and gel electrophoresis. Moreover, expression of individual variants differed between dysplasia and carcinoma to suggest their disease dependent regulation. Western blotting of IQGAP1, MYO6, PTPRM, RABGAP1L and RAD50 confirmed significant regulation of isoforms in lung cancer as compared to non-transgenic, transgenic unaltered and dysplastic lung tissue. For 46 AS genes expression of the non-variant protein was reported in human lung cancer (www.proteinatlas.org) and for 13 of these, cancer related AS events are known. Overall, new insight into lung dysplasia was obtained with 43 new cancer related AS genes to aid diagnosis and molecular intervention strategies. Overall design: We analyzed and compared dysplastic (n=4) and adenocarcinoma (n=4) lesions and with transgenic but unaltered (n=4) and non-transgenic (n=5) lung tissue obtained from SPC/c-Raf transgenic mice with aid of laser micro dissection pressure catapulted (LMPC) technique. Dysplasia is a pre-neoplastic condition and developed at 5 month of age in the proposed mouse model. LMPC provides precise microscopic lesion collection without contamination. The RNA samples were analyzed using the Affymetrix Mouse Exon 1.0 ST platform. Alternative splicing was...
  16. A whole genome map of alternative splicing events in precancerous lung dysplasia and adenocarcinomas of c-Raf mice OmicsDI

    ID: E-GEOD-38948

    Date Released: 06-28-2014

    Description: script and protein level agreed well, whereas for Arhgef11, Clstn1, Dlg1, Dock9, Mbnl2, Mfge8, Npnt, Pdlim5, Ppp2r5c, Tjp1 notable differences in the abundance of variant transcripts were observed by RT-PCR and gel electrophoresis. Moreover, expression of individual variants differed between dysplasia and carcinoma to suggest their disease dependent regulation. Western blotting of IQGAP1, MYO6, PTPRM, RABGAP1L and RAD50 confirmed significant regulation of isoforms in lung cancer as compared to non-transgenic, transgenic unaltered and dysplastic lung tissue. For 46 AS genes expression of the non-variant protein was reported in human lung cancer (www.proteinatlas.org) and for 13 of these, cancer related AS events are known. Overall, new insight into lung dysplasia was obtained with 43 new cancer related AS genes to aid diagnosis and molecular intervention strategies. We analyzed and compared dysplastic (n=4) and adenocarcinoma (n=4) lesions and with transgenic but unaltered (n=4) and non-transgenic (n=5) lung tissue obtained from SPC/c-Raf transgenic mice with aid of laser micro dissection pressure catapulted (LMPC) technique. Dysplasia is a pre-neoplastic condition and developed at 5 month of age in the proposed mouse model. LMPC provides precise microscopic lesion collection without contamination. The RNA samples were analyzed using the Affymetrix Mouse Exon 1.0 ST platform. Alternative splicing was analyzed using ...


Displaying 16 of 16 results for "ARHGEF11"