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Displaying 20 of 34 results for "APRT"
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  1. Kidney Stone Induces Developmental Stage-specific Alterations in Gene Expression BioProject

    ID: PRJNA119463

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ODS: Mice with adenine phosphoribosyltransferase (Aprt) deficiency develop 2,8-dihydroxyadenine (DHA) nephrolithiasis. Gene expression changes between Aprt-/- and Aprt+/+ kidneys from newborn and adult mice were compared using Affymetrix gene chips. RESULTS: We observed that: (i) gene expression changes induced by Aprt deficiency are developmental stage-specific; (ii) maturation-related gene expression changes are delayed in developing Aprt-/- kidneys; a...
  2. Kidney Stone Induces Developmental Stage-specific Alterations in Gene Expression ArrayExpress

    ID: E-GEOD-18160

    Description: ODS: Mice with adenine phosphoribosyltransferase (Aprt) deficiency develop 2,8-dihydroxyadenine (DHA) nephrolithiasis. Gene expression changes between Aprt-/- and Aprt+/+ kidneys from newborn and adult mice were compared using Affymetrix gene chips. RESULTS: We observed that: (i) gene expression changes induced by Aprt deficiency are developmental stage-specific; (ii) maturation-related gene expression changes are delayed in developing Aprt-/- kidneys; a...

  3. Kidney Stone Induces Developmental Stage-specific Alterations in Gene Expression OmicsDI

    ID: E-GEOD-18160

    Date Released: 06-02-2014

    Description: ODS: Mice with adenine phosphoribosyltransferase (Aprt) deficiency develop 2,8-dihydroxyadenine (DHA) nephrolithiasis. Gene expression changes between Aprt-/- and Aprt+/+ kidneys from newborn and adult mice were compared using Affymetrix gene chips. RESULTS: We observed that: (i) gene expression changes induced by Aprt deficiency are developmental stage-specific; (ii) maturation-related gene expression changes are delayed in developing Aprt-/- kidneys; a...

  4. Crystal Structure of F173G Mutant of Human APRT PDB

    ID: PDB:4X45

    Description: Human adenine phosphoribosyltransferase (E.C.2.4.2.7)

  5. Crystal structure of an APRT from Yersinia pseudotuberculosis in complex with AMP. PDB

    ID: PDB:5B6H

    Description: Adenine phosphoribosyltransferase (E.C.2.4.2.7)

  6. Crystal Structure of Adenine Phosphoribosyltransferase (APRT) From Leishmania tarentolae PDB

    ID: PDB:1MZV

    Description: Adenine Phosphoribosyltransferase (E.C.2.4.2.7)

  7. Human Adenine Phosphoribosyltransferase Complexed with PRPP, ADE and R5P PDB

    ID: PDB:1ZN7

    Description: Adenine phosphoribosyltransferase (E.C.2.4.2.7)

    gene.name: APRT
  8. Crystal Structure of Mutant R89Q of human Adenine phosphoribosyltransferase PDB

    ID: PDB:4X44

    Description: Adenine phosphoribosyltransferase (E.C.2.4.2.7)

    gene.name: APRT
  9. Comparative genomic hybridization by array of mouse Blm-deficient embryonic stem cells to study double strand break (DSB)-induced loss of heterozygosi... ArrayExpress

    ID: E-MTAB-1116

    Description: site of I-SceI endonuclease was introduced in the Aprt gene in Blm-deficient mESCs. We used two types of I-SceI expression vectors; one expresses a mammalian codon-optimized I-SceI (ISceIo) and the other expresses I-SceIo fused with N-terminal 110-amino acids of Geminin (Gemi). Geminin-fused I-SceI can be stabilized only in lateS/G2 phase. After I-SceI transfection and subsequent selection, we isolated Aprt-deficient mutants. Half of the mutants showed LOH in the whole telomeric region from I-SceI site, but the other half showed local LOH near the I-SceI site. Further analyses suggested that large deletion was introduced and caused LOH, which was not seen in spontaneous LOH. We designed CGH probes in 300-bp resolution in 8Mb telomeric region of chr 8 (The Aprt gene locates 7Mb from the telomere) to map the deleted regions in these mutants....

  10. Human Adenine Phosphoribosyltransferase in Apo and AMP Complexed Forms PDB

    ID: PDB:1ZN9

    Description: Adenine phosphoribosyltransferase (E.C.2.4.2.7)

    gene.name: APRT
  11. Human Adenine Phosphoribosyltransferase Complexed with AMP, in Space Group P1 at 1.76 A Resolution PDB

    ID: PDB:1ZN8

    Description: Adenine phosphoribosyltransferase (E.C.2.4.2.7)

    gene.name: APRT
  12. Comparative genomic hybridization by array of mouse Blm-deficient embryonic stem cells to study double strand break (DSB)-induced loss of heterozygosi... OmicsDI

    ID: E-MTAB-1116

    Date Released: 05-03-2014

    Description: site of I-SceI endonuclease was introduced in the Aprt gene in Blm-deficient mESCs. We used two types of I-SceI expression vectors; one expresses a mammalian codon-optimized I-SceI (ISceIo) and the other expresses I-SceIo fused with N-terminal 110-amino acids of Geminin (Gemi). Geminin-fused I-SceI can be stabilized only in lateS/G2 phase. After I-SceI transfection and subsequent selection, we isolated Aprt-deficient mutants. Half of the mutants showed LOH in the whole telomeric region from I-SceI site, but the other half showed local LOH near the I-SceI site. Further analyses suggested that large deletion was introduced and caused LOH, which was not seen in spontaneous LOH. We designed CGH probes in 300-bp resolution in 8Mb telomeric region of chr 8 (The Aprt gene locates 7Mb from the telomere) to map the deleted regions in these mutants....

  13. Human Adenine Phosphoribosyltransferase PDB

    ID: PDB:1ORE

    Description: Adenine phosphoribosyltransferase (E.C.2.4.2.7)

    gene.name: APRT
  14. APT_DIPCP UniProt:Swiss-Prot

    ID: Q64414

    Description: Removed Adenine phosphoribosyltransferase N-acetylalanine Phosphoserine Phosphoserine Phosphotyrosine Phosphoserine N6-acetyllysine Phosphothreonine

    gene.name: APRT
  15. APT_MASHI UniProt:Swiss-Prot

    ID: Q64427

    Description: Removed Adenine phosphoribosyltransferase N-acetylserine Phosphoserine Phosphoserine Phosphotyrosine Phosphoserine N6-acetyllysine Phosphothreonine

    gene.name: APRT
  16. Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis. PDB

    ID: PDB:4MB6

    Description: Adenine phosphoribosyltransferase (E.C.2.4.2.7)

    dataset.keywords: APRT
  17. APT_CRIGR UniProt:Swiss-Prot

    ID: P47952

    Description: Removed Adenine phosphoribosyltransferase N-acetylalanine Phosphoserine Phosphoserine Phosphoserine Phosphotyrosine Phosphoserine N6-acetyllysine Phos...

    gene.name: APRT
  18. APT_MUSSI UniProt:Swiss-Prot

    ID: P47957

    Description: Removed Adenine phosphoribosyltransferase N-acetylserine Phosphoserine Phosphoserine Phosphotyrosine Phosphoserine N6-acetyllysine Phosphothreonine

    gene.name: Aprt
  19. APT_RAT UniProt:Swiss-Prot

    ID: P36972

    Description: Removed Adenine phosphoribosyltransferase N-acetylserine Phosphoserine Phosphoserine Phosphoserine Phosphotyrosine Phosphoserine N6-acetyllysine Phosp...

    gene.name: Aprt
  20. APT_BOVIN UniProt:Swiss-Prot

    ID: Q56JW4

    Description: Removed Adenine phosphoribosyltransferase N-acetylalanine Phosphoserine Phosphoserine Phosphotyrosine Phosphoserine Phosphothreonine

    gene.name: APRT

Displaying 20 of 34 results for "APRT"