APOB | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 74 results for "APOB"
i
  1. ApoB alignment Dryad

    DateIssued: 10-29-2015

    Description: Ninety-two samples of sequence data from the ApoB gene across jumping mice including N. insignis (5 subspecies), Z. hudsonius (12 subspecies), Z. princeps (10 subspecies), and ...

  2. siRNAs induced long-term liver ApoB mRNA knockdown significantly lowers serum cholesterol in a mouse model with human-like serum lipids BioProject

    ID: PRJNA131887

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Evidence of mechanism how rs7575840 influences apolipoprotein B containing lipid particles ArrayExpress

    ID: E-GEOD-27666

    Description: fied a variant rs7575840 in the apolipoprotein B (APOB) gene region to be associated with LDL-C. However, the underlying functional mechanism of this variant that resides 6.5 kb upstream of APOB has remained unknown. Our obje...

  4. siRNAs induced long-term liver ApoB mRNA knockdown significantly lowers serum cholesterol in a mouse model with human-like serum lipids OmicsDI

    ID: E-GEOD-23088

    Date Released: 11-27-2011

    Description: Increased serum apoB and associated low density lipoprotein cholesterol (LDL) levels are well correlated with an increased risk of coronary disease...

  5. siRNAs induced long-term liver ApoB mRNA knockdown significantly lowers serum cholesterol in a mouse model with human-like serum lipids ArrayExpress

    ID: E-GEOD-23088

    Description: Increased serum apoB and associated low density lipoprotein cholesterol (LDL) levels are well correlated with an increased risk of coronary disease...

  6. Evidence of mechanism how rs7575840 influences apolipoprotein B containing lipid particles BioProject

    ID: PRJNA138477

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: fied a variant rs7575840 in the apolipoprotein B (APOB) gene region to be associated with LDL-C. However, the underlying functional mechanism of this variant that resides 6.5 kb upstream of APOB has remained unknown. Our obje...
  7. Evidence of mechanism how rs7575840 influences apolipoprotein B containing lipid particles OmicsDI

    ID: E-GEOD-27666

    Date Released: 09-14-2011

    Description: fied a variant rs7575840 in the apolipoprotein B (APOB) gene region to be associated with LDL-C. However, the underlying functional mechanism of this variant that resides 6.5 kb upstream of APOB has remained unknown. Our obje...

  8. Homo sapiens : Metabolism and Genetics of Hypobetalipoproteinemia: Population Screen BioProject

    ID: PRJNA178383

    Access Type: download

    dataset.description: ypobetalipoproteinemia caused by mutations in the APOB gene. There are cases of hypobetalipoproteinemia not caused by mutations in APOB, however. The purpose of this study is to identify novel genetic causes of hypobetalipoproteinemia....
  9. NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor PDB

    ID: PDB:1YLG

    Description: 31-MER

  10. ApoB alignment Dryad

    DateIssued: 08-24-2016

    Description: Nexus file containing phased alleles from ApoB sequences of Sunda shelf Crocidura. This alignment was used to generate the gene trees in Figures S1 and S2....

  11. NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor PDB

    ID: PDB:1YNG

    Description: 31-MER

  12. NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor PDB

    ID: PDB:1YNC

    Description: 31-MER

  13. ApoB sequences 2 Dryad

    DateIssued: 08-24-2016

    Description: Nexus file containing phased alleles from ApoB sequences of Sunda shelf Crocidura. This alignment was used to generate the species tree in Fig. 3....

  14. NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor PDB

    ID: PDB:1YNE

    Description: 31-MER

  15. Comparison between Caenorhabditis elegans wild-type and Nep-1 mutant strains OmicsDI

    ID: E-GEOD-32339

    Date Released: 10-12-2011

    Description: of the vit3 mammalian homologue, Apoliporotein B (APOB), were performed in the murine Neuro2a cell line, a model of ENS development. Apob expression in Neuro2a is specifically activated by the RET/GDNF signalling pathway, since Ret silencing abolished Apob increase, and this effect is induced by MAPK P38 kinase activation. Mouse Apob promoter study revealed that there is a p53-dependent repressor element in the promoter region which blocks Apob expression and we show that actually p53 binds to this region. We demonstrated that RET/GDNF and EDNRB/endothelin 3 (ET-3) cooperate in inducing neuronal differentiation resulting in Apob activation. We also show that Apob

  16. Comparison between Caenorhabditis elegans wild-type and Nep-1 mutant strains ArrayExpress

    ID: E-GEOD-32339

    Description: of the vit3 mammalian homologue, Apoliporotein B (APOB), were performed in the murine Neuro2a cell line, a model of ENS development. Apob expression in Neuro2a is specifically activated by the RET/GDNF signalling pathway, since Ret silencing abolished Apob increase, and this effect is induced by MAPK P38 kinase activation. Mouse Apob promoter study revealed that there is a p53-dependent repressor element in the promoter region which blocks Apob expression and we show that actually p53 binds to this region. We demonstrated that RET/GDNF and EDNRB/endothelin 3 (ET-3) cooperate in inducing neuronal differentiation resulting in Apob activation. We also show that Apob

  17. Metabolism and Genetics of Hypobetalipoproteinemia: Population Screen BioProject

    ID: PRJNA178384

    Keywords: Phenotype or Genotype

    Access Type: download

    dataset.description: ypobetalipoproteinemia caused by mutations in the APOB gene. There are cases of hypobetalipoproteinemia not caused by mutations in APOB, however. The purpose of this study is to identify novel genetic causes of hypobetalipoproteinemia....
  18. RM709_RNA : A transposable element insertion in APOB causes cholesterol deficiency in Holstein cattle BioProject

    ID: PRJEB11963

    Keywords: Other

    Access Type: download

  19. Comparison between Caenorhabditis elegans wild-type and Nep-1 mutant strains BioProject

    ID: PRJNA147249

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: of the vit3 mammalian homologue, Apoliporotein B (APOB), were performed in the murine Neuro2a cell line, a model of ENS development. Apob expression in Neuro2a is specifically activated by the RET/GDNF signalling pathway, since Ret silencing abolished Apob increase, and this effect is induced by MAPK P38 kinase activation. Mouse Apob promoter study revealed that there is a p53-dependent repressor element in the promoter region which blocks Apob expression and we show that actually p53 binds to this region. We demonstrated that RET/GDNF and EDNRB/endothelin 3 (ET-3) cooperate in inducing neuronal differentiation resulting in Apob activation. We also show that Apob
  20. The RNA-binding protein Hdlbp/Vigilin is increased in hepatic steatosis and regulates VLDL secretion through modulation of Apob mRNA translation BioProject

    ID: PRJNA312585

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 20 of 74 results for "APOB"