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Displaying 20 of 40 results for "ANXA1"
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  1. miRNA expression data from MCF-7 cells, overexpressing ANXA1 BioProject

    ID: PRJNA236526

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. miRNA expression data from MCF-7 cells, overexpressing ANXA1 OmicsDI

    ID: E-GEOD-54439

    Date Released: 01-10-2015

    Description: Annexin 1 (ANXA1), an endogenous anti-inflammatory protein which modulates cellular processes such as proliferation, differentiation and apopt...

  3. miRNA expression data from MCF-7 cells, overexpressing ANXA1 ArrayExpress

    ID: E-GEOD-54439

    Description: Annexin 1 (ANXA1), an endogenous anti-inflammatory protein which modulates cellular processes such as proliferation, differentiation and apopt...

  4. Transcription profiling by array of human breast cancer cell line BT-474 with annexin A1 over-expression or silenced with siRNA to demonstrate design ... ArrayExpress

    ID: E-MEXP-2775

    Description: ines for overexpressing and silencing annexin A1 (ANXA1), which belongs to a family of -dependent phospholipid binding proteins and are preferentially located on the cytosolic face of the plasma membrane. Cell lines overexpressing ANXA1 (MDA_MB-453/cDNA) were generated by introducing retroviral vectors containing ANXA1 cDNA (pBabe/ANXA1 cDNA) into breast cancer cell line MDA-MB-453 (a low expressor of

  5. Transcription profiling by array of human breast cancer cell line BT-474 with annexin A1 over-expression or silenced with siRNA to demonstrate design ... OmicsDI

    ID: E-MEXP-2775

    Date Released: 05-02-2014

    Description: ines for overexpressing and silencing annexin A1 (ANXA1), which belongs to a family of -dependent phospholipid binding proteins and are preferentially located on the cytosolic face of the plasma membrane. Cell lines overexpressing ANXA1 (MDA_MB-453/cDNA) were generated by introducing retroviral vectors containing ANXA1 cDNA (pBabe/ANXA1 cDNA) into breast cancer cell line MDA-MB-453 (a low expressor of

  6. STRUCTURE OF FULL-LENGTH ANNEXIN A1 IN THE PRESENCE OF CALCIUM PDB

    ID: PDB:1MCX

    Description: ANNEXIN I

    gene.name: ANXA1
  7. Annexin A1 interacting proteins in chronic myeloid leukemia KCL22 cells OmicsDI

    ID: PXD000030

    Date Released: 08-13-2013

    Description: tional proteomic approach to identify Annexin A1 (Anxa1) interacting proteins in the Philadelphia-positive KCL22 cell line. We focused on Anxa1 because it is one of the major proteins upregulated in...

  8. Essential role of formyl peptide receptor 1 in anthracycline-based anticancer chemotherapy ArrayExpress

    ID: E-GEOD-63410

    Description: en tumor cells lacked the FPR1 ligand Annexin A1 (ANXA1). Defective anticancer immune responses from FPR1 knockout mice could be attributed to the failure of dendritic cells to approach dying tumor cells and hence to present tumor cell antigens to T lymphocytes. Experiments performed in a microfluidic device confirmed the obligatory contribution of ANXA1 and FPR1 to the induction of stable conjugates between dying tumor cells and human or murine leukocytes. Altogether, these results underscore the functional and clinical importance of FPR1 in determining chemotherapy-relevant anticancer immune responses. When the surface of tumor reached 25-45 mm2 after subcutaneous tumor cell innoculation, mice received 2.9 mg/Kg intratumoral doxorubicin (DX) (in 50 μL PBS). Two days after treatment, tumor samples were harvested, rinsed briefly with cold PBS and immediately preserved in RNAlater RNA Sta...

  9. FAK and HAS3 inhibition affect the expression of several common genes ArrayExpress

    ID: E-GEOD-39168

    Description: , IL20RA, INHBE, SCNN1A) and 4 were up-regulated (ANXA1, MALL, RGS2, SNAI2). RT-PCR confirmed these findings. Among the genes affected by FAK or HAS3 inhibition were FOX genes (apoptosis, cell cycle regulation), ANXA1 (apoptosis, proliferation), IL8 (cell cycle regulation, adhesion, proliferation), RGS2 (cell cycle regulation), CEACAM6 (adhesion), SNAI2 (transcription regulation), and SFRP5 (apoptosis). Several genes were specific to either FAK or HAS3 inhibition and several were common to both. Gene expression profiles of samples isolated from human colorectal cancer cells (SW620). A comparison of gene expression between untreated cells and cells treated with 4mcM of Y15. A second comparison between cells transfected with siRNA to HAS3 (HAS3-silenced) and cells transfected with a scrambled control sequence (sc). Two replicates each....

  10. Essential role of formyl peptide receptor 1 in anthracycline-based anticancer chemotherapy OmicsDI

    ID: E-GEOD-63410

    Date Released: 04-10-2016

    Description: en tumor cells lacked the FPR1 ligand Annexin A1 (ANXA1). Defective anticancer immune responses from FPR1 knockout mice could be attributed to the failure of dendritic cells to approach dying tumor cells and hence to present tumor cell antigens to T lymphocytes. Experiments performed in a microfluidic device confirmed the obligatory contribution of ANXA1 and FPR1 to the induction of stable conjugates between dying tumor cells and human or murine leukocytes. Altogether, these results underscore the functional and clinical importance of FPR1 in determining chemotherapy-relevant anticancer immune responses. When the surface of tumor reached 25-45 mm2 after subcutaneous tumor cell innoculation, mice received 2.9 mg/Kg intratumoral doxorubicin (DX) (in 50 μL PBS). Two days after treatment, tumor samples were harvested, rinsed briefly with cold PBS and immediately preserved in RNAlater RNA Sta...

  11. Transcription profiling of human peripheral blood monocytes treated with Annexin A1 Ac1-25 vs. unstimulated ArrayExpress

    ID: E-GEOD-9080

    Description: We used microarrays to detail the global gene expression changes elicited by stimulation of human peripheral blood monocytes from buffy coats with 50...

  12. Transcription profiling by array of human neutrophils after 30 minutes' exercise ArrayExpress

    ID: E-GEOD-8668

    Description: 32, TNFSF8 and CCR5) and anti-inflammatory (e.g., ANXA1) were affected. Growth and repair genes like AREG and FGF2 receptor genes (involved in angiogenesis) were also activated. Finally, a number of neutrophil genes known to be involved in pathological conditions like asthma and arthritis were altered by exercise, suggesting novel links between physical activity and disease or its prevention. In summary, brief heavy exercise leads to a previously unknown substantial and significant alteration in neutrophil gene expression. Experiment Overall Design: Twelve healthy men (19-29 yr old) participated in this study. A baseline blood sample was taken before the onset of exercise and immediately after 30-min exercise bout. Neutrophils were isolated using OptiPrep Density Gradient Medium (SIGMA). Total RNA was extracted using TRIzol. cRNA was hybridized onto Affymetrix U133+2 arrays (total of 24 chips)....

  13. S100C (S100A11),OR CALGIZZARIN, IN COMPLEX WITH ANNEXIN I N-TERMINUS PDB

    ID: PDB:1QLS

    Description: S100C PROTEIN, ANNEXIN I

  14. Fixed single-cell transcriptomic characterization of human radial glial diversity BioProject

    ID: PRJNA292324

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: o ventricle zone-enriched RG (vRG) that expressed ANXA1 and CRYAB, and outer subventricular zone-localized RG (oRG) that expressed HOPX. Our study identified the first markers and molecular profiles of vRG and oRG cells, and provides an essential step for understanding molecular networks that control the development and lineage of human neocortical progenitors. Furthermore, FRSCR allows targeted single-cell transcriptomic profiling of many tissues that currently lack live-cell markers. Overall design: 26 Llive and 19 Fixed cultured hESCs were prepared and sequenced using both FRISCR and TritonX-100 Lysis as proof of principal for FRSCR....
  15. FAK and HAS3 inhibition affect the expression of several common genes BioProject

    ID: PRJNA170130

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: , IL20RA, INHBE, SCNN1A) and 4 were up-regulated (ANXA1, MALL, RGS2, SNAI2). RT-PCR confirmed these findings. Among the genes affected by FAK or HAS3 inhibition were FOX genes (apoptosis, cell cycle regulation), ANXA1 (apoptosis, proliferation), IL8 (cell cycle regulation, adhesion, proliferation), RGS2 (cell cycle regulation), CEACAM6 (adhesion), SNAI2 (transcription regulation), and SFRP5 (apoptosis). Several genes were specific to either FAK or HAS3 inhibition and several were common to both. Overall design: Gene expression profiles of samples isolated from human colorectal cancer cells (SW620). A comparison of gene expression between untreated cells and cells treated with 4mcM of Y15. A second comparison between cells transfected with siRNA to HAS3 (HAS3-silenced) and cells transfected with a scrambled control sequence (sc). Two replicates each....
  16. Essential role of formyl peptide receptor 1 in anthracycline-based anticancer chemotherapy BioProject

    ID: PRJNA267689

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: en tumor cells lacked the FPR1 ligand Annexin A1 (ANXA1). Defective anticancer immune responses from FPR1 knockout mice could be attributed to the failure of dendritic cells to approach dying tumor cells and hence to present tumor cell antigens to T lymphocytes. Experiments performed in a microfluidic device confirmed the obligatory contribution of ANXA1 and FPR1 to the induction of stable conjugates between dying tumor cells and human or murine leukocytes. Altogether, these results underscore the functional and clinical importance of FPR1 in determining chemotherapy-relevant anticancer immune responses. Overall design: When the surface of tumor reached 25-45 mm2 after subcutaneous tumor cell innoculation, mice received 2.9 mg/Kg intratumoral doxorubicin (DX) (in 50 μL PBS). Two days after treatment, tumor samples were harvested, rinsed briefly with cold PBS and immediately preserved in ...
  17. CRYSTAL STRUCTURE OF HUMAN ANNEXIN I AT 2.5 ANGSTROMS RESOLUTION PDB

    ID: PDB:1AIN

    Description: ANNEXIN I

  18. An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease PDB

    ID: PDB:5VFW

    Description: Annexin A1

  19. NMR SOLUTION STRUCTURE OF DOMAIN 1 OF HUMAN ANNEXIN I PDB

    ID: PDB:1BO9

    Description: PROTEIN (ANNEXIN I)

  20. ANXA1_PONAB UniProt:Swiss-Prot

    ID: Q5REL2

    Description: Removed Annexin A1 Annexin 1 Annexin 2 Annexin 3 Annexin 4 Calcium 1; via carbonyl oxygen Calcium 1; via carbonyl oxygen Calcium 1 Calcium 2; via carb...

    gene.name: ANXA1

Displaying 20 of 40 results for "ANXA1"