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Displaying 20 of 153 results for "AJAP1"
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  1. AJAP1_XENTR UniProt:Swiss-Prot

    ID: Q0IIY7

    Description: Adherens junction-associated protein 1 Extracellular Helical Cytoplasmic T...

  2. Cell Image Library Dataset CIL:7621 CIL

    ID: 7621

    Description: ) located nearest to the lumen extends from arrow 1 to arrow 2. The elimination of the intercellular gap (approx 90 angstroms) is clearly visible, but the fusion line of the two apposed membranes cannot be clearly distinguished at this magnification. The adherens junction (also known as zonula

    Data Types: image

  3. Smoking-induced Disarray of the Apical Junctional Complex Gene Expression Architecture in the Human Airway Epithelium ArrayExpress

    ID: E-GEOD-20257

    Description: pical junctional complex (AJC), composed of tight junctions and adherens junctions, is essential for maintaining epithelial barrier function. Since ...

  4. Cell Image Library Dataset CIL:7620 CIL

    ID: 7620

    Description: clearly distinguished at this magnification. The adherens junction (also known as zonula adherens) is the next structure. A relatively wide intercellular space (approx 200 angstroms) is maintained throughout this junction. Extensive actin filament networks are seen along both sides of the junction which are continuous with the terminal web into which the filamentous rootlets of the mircovilli penetrate. Dense material can be seen along parts of both sides of the junction. The limit...

    Data Types: image

  5. Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells ArrayExpress

    ID: E-GEOD-70175

    Description: ere observed in a subset of genes including MGMT, AJAP1 and PTPRN2. These unique DNA methylation signatures were also found in primary GBM-derived xenograft tumors indicating that they are not tissue culture-related epigenetic changes. Integration of GSC-specific epigenetic signatures with gene expression analysis further identified candidate tumor suppressor genes that are frequently down regulated in GBMs such as SPINT2, NEFM and PENK. Forced re-expression of SPINT2 reduced glioma cell proliferative capacity, anchorage independent growth, cell motility, and tumor sphere formation in vitro. The results from this study demonstrate that GSCs possess unique epigenetic signatures that may play important roles in the pathogenesis of GBM. The reduced representation bisulfite sequencing (RRBS) approach (Meissner et al., 2008) was used to generate genome-wide single-base resolution CpG methylation profiles of three primary GBMs (1063T, 1133T, and 1142T) and three GSC lines (1063S, 1133S, 1142S) derived from these primary GBM tumors. The NSC line and the norm...

  6. LSEC: a microenvironment dependent differentiation program in rat including the novel junctional protein Leda-1 OmicsDI

    ID: E-GEOD-20375

    Date Released: 06-10-2011

    Description: rovascular differentiation and functions. Disease-associated capillarization of LSEC in vivo and dedifferentiation of LSEC in vitro indicate the importance of the hepatic microenvironment. To identify the LSEC-specific molecular differentiation program in th...

  7. Transcriptome sequencing of Chinese tree shrew, Tupaia belangeri chinensis ArrayExpress

    ID: E-GEOD-39150

    Description: Deep sequencing of mRNA from Chinese tree shrew; Chinese tree shrew (Tupaia belangeri chinensis) is placed in Order Scandentia and embraces many unique fe...

  8. ion program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1... BioProject

    ID: PRJNA125481

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. LSEC: a microenvironment dependent differentiation program in rat including the novel junctional protein Leda-1 ArrayExpress

    ID: E-GEOD-20375

    Description: rovascular differentiation and functions. Disease-associated capillarization of LSEC in vivo and dedifferentiation of LSEC in vitro indicate the importance of the hepatic microenvironment. To identify the LSEC-specific molecular differentiation program in th...

  10. Role of SPI-1 Secreted Effectors, SipA, SopABDE2, in Acute Bovine Response to Salmonella enterica Serovar Typhimurium ArrayExpress

    ID: E-GEOD-13847

    Description: ion System encoded at Pathogenicity Island I (SPI-1) translocates the Salmonella effector proteins SipA, SopA, SopB, SopD, and SopE2 into the host epithelial cell cytoplasm. These five effector proteins act in concert to induce fluid secretion and transcription of C-X-C chemokines, which serve to recruit PMNs to the intestine. While the individual molecular interactions of these Salmonella proteins w...

  11. Role of SPI-1 Secreted Effectors, SipA, SopABDE2, in Acute Bovine Response to Salmonella enterica Serovar Typhimurium BioProject

    ID: PRJNA110527

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Aberrant DNA methylation epigenotype expanding to non-polycomb target genes, induced by Epstein-Barr virus infection in human gastric cancer [Illumina... BioProject

    ID: PRJNA155059

    Keywords: Epigenomics

    Access Type: download

    dataset.description: astric cancer (Common-markers, e.g. AMPH, SORCS3, AJAP1). Polycomb repressive complex (PRC)-target genes in ES cells were significantly enriched in High- and Common-markers (P=2x10-15 and 2x10-34, respectively), but not in EBV(+)-markers (P=0.2), suggesting a different cause for EBV(+)-marker methylation. Recombinant EBV was infected to low epigenotype gastric cancer cell, MKN7. In all the three independently established clones, DNA methylation was induced in High- and EBV(+)-markers after 18 weeks, demonstrating that EBV-positive epigenotype should involve methylation of Common-, High-, and EBV(+)-markers simultaneously. The de novo methylated genes were overlapped well among the three clones, and the methylation caused gene repression. In summary, gastric cancer was classified into three DNA methylation epigenotypes, EBV-positive gastric cancer showed markedly high methylation epigenotype expanding to non-PRC target genes, and EBV infection per se could induce the EBV-positive epigenotype. Overall design: 51 clinical gastric cancer samples including 1...
  13. Leptospira alstonii strain:GWTS #1 : Leptospira alstonii serovar Room22 Genome sequencing and assembly BioProject

    ID: PRJNA315006

    Keywords: Genome sequencing

    Access Type: download

  14. Aberrant DNA methylation epigenotype expanding to non-polycomb target genes, induced by Epstein-Barr virus infection in human gastric cancer [Affymetr... BioProject

    ID: PRJNA155057

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: astric cancer (Common-markers, e.g. AMPH, SORCS3, AJAP1). Polycomb repressive complex (PRC)-target genes in ES cells were significantly enriched in High- and Common-markers (P=2x10-15 and 2x10-34, respectively), but not in EBV(+)-markers (P=0.2), suggesting a different cause for EBV(+)-marker methylation. Recombinant EBV was infected to low epigenotype gastric cancer cell, MKN7. In all the three independently established clones, DNA methylation was induced in High- and EBV(+)-markers after 18 weeks, demonstrating that EBV-positive epigenotype should involve methylation of Common-, High-, and EBV(+)-markers simultaneously. The de novo methylated genes were overlapped well among the three clones, and the methylation caused gene repression. In summary, gastric cancer was classified into three DNA methylation epigenotypes, EBV-positive gastric cancer showed markedly high methylation epigenotype expanding to non-PRC target genes, and EBV infection per se could induce the EBV-positive epigenotype. Overall design: 3 EBV(+) clones and 1 mock ...
  15. Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells BioProject

    ID: PRJNA287801

    Keywords: Epigenomics

    Access Type: download

    dataset.description: ere observed in a subset of genes including MGMT, AJAP1 and PTPRN2. These unique DNA methylation signatures were also found in primary GBM-derived xenograft tumors indicating that they are not tissue culture-related epigenetic changes. Integration of GSC-specific epigenetic signatures with gene expression analysis further identified candidate tumor suppressor genes that are frequently down regulated in GBMs such as SPINT2, NEFM and PENK. Forced re-expression of SPINT2 reduced glioma cell proliferative capacity, anchorage independent growth, cell motility, and tumor sphere formation in vitro. The results from this study demonstrate that GSCs possess unique epigenetic signatures that may play important roles in the pathogenesis of GBM. Overall design: The reduced representation bisulfite sequencing (RRBS) approach (Meissner et al., 2008) was used to generate genome-wide single-base resolution CpG methylation profiles of three primary GBMs (1063T, 1133T, and 1142T) and three GSC lines (1063S, 1133S, 1142S) derived from these primary GBM tumors. The NSC l...
  16. Identification of Global DNA Methylation Signatures in Glioblastoma-Derived Cancer Stem Cells OmicsDI

    ID: E-GEOD-70175

    Date Released: 06-27-2015

    Description: ere observed in a subset of genes including MGMT, AJAP1 and PTPRN2. These unique DNA methylation signatures were also found in primary GBM-derived xenograft tumors indicating that they are not tissue culture-related epigenetic changes. Integration of GSC-specific epigenetic signatures with gene expression analysis further identified candidate tumor suppressor genes that are frequently down regulated in GBMs such as SPINT2, NEFM and PENK. Forced re-expression of SPINT2 reduced glioma cell proliferative capacity, anchorage independent growth, cell motility, and tumor sphere formation in vitro. The results from this study demonstrate that GSCs possess unique epigenetic signatures that may play important roles in the pathogenesis of GBM. The reduced representation bisulfite sequencing (RRBS) approach (Meissner et al., 2008) was used to generate genome-wide single-base resolution CpG methylation profiles of three primary GBMs (1063T, 1133T, and 1142T) and three GSC lines (1063S, 1133S, 1142S) derived from these primary GBM tumors. The NSC line and the norm...

  17. B-Raf inhibitors induce epithelial differentiation in BRAF mutant colorectal cancer cells ArrayExpress

    ID: E-GEOD-50791

    Description: oto-oncogene, which encodes the B-Raf kinase, are associated with more aggressive, less-differentiated and therapy-resistant colorectal cancers (CRC). However, the molecular mechanisms responsible for thes...

  18. camera trap data Dryad

    DateIssued: 05-29-2015

    Description: A dataset of collected by nine below-snow camera traps. See metadata file for detailed description.

    dataset.keywords.raw: shrew
  19. snow cover camera traps Dryad

    DateIssued: 05-29-2015

    Description: Records of snow cover at camera trap locations. See metadata file for more detailed description.

    dataset.keywords.raw: shrew
  20. Data from: Under the snow: a new camera trap opens the white box of subnivean ecology Dryad

    DateIssued: 11-02-2015

    Description: mammal species present (the insectivorous common shrew, Sorex araneus, the herbivorous tundra vole, Microtus oeconomus, and the carnivorous stoat, Mustela erminea) as well as abiotic conditions (presence/absence of snow cover and subnivean temperature). Based on their successful functioning (only 6% of the photographs appeared empty or were of poor quality, whereas ca 80% were of small mammals and the remaining of birds and invertebrates), we discuss how the new camera trap can enable subnivean studies of small mammal communities. This greatly increases the temporal resolution and extent of data collection and thereby provides unpreceded opportunities to understand population and food web dynamics in ecosystems with snow cover....


Displaying 20 of 153 results for "AJAP1"