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Displaying 12 of 12 results for "AFF3"
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  1. A permissive chromatin state regulated by ZFP281-AFF3 in controlling the imprinted Meg3 polycistron BioProject

    ID: PRJNA309462

    Keywords: Other

    Access Type: download

  2. Allele-specific regulation of gene expression through enhancer function and transcriptional elongation control at imprinted loci BioProject

    ID: PRJNA271109

    Keywords: Other

    Access Type: download

    dataset.description: Here, we have identified the AFF family protein, Aff3, as a factor that functionally interacts with imprinted loci. Indeed, our genome-wide studies demonstrate that Aff3 specifically binds both imprinting control regions (ICRs) and enhancers within imprinted loci in an allele-...
  3. Allele-specific regulation of gene expression through enhancer function and transcriptional elongation control at imprinted loci ArrayExpress

    ID: E-GEOD-64489

    Description: Here, we have identified the AFF family protein, Aff3, as a factor that functionally interacts with imprinted loci. Indeed, our genome-wide studies demonstrate that Aff3 specifically binds both imprinting control regions (ICRs) and enhancers within imprinted loci in an allele-...

  4. Allele-specific regulation of gene expression through enhancer function and transcriptional elongation control at imprinted loci OmicsDI

    ID: E-GEOD-64489

    Date Released: 01-10-2016

    Description: Here, we have identified the AFF family protein, Aff3, as a factor that functionally interacts with imprinted loci. Indeed, our genome-wide studies demonstrate that Aff3 specifically binds both imprinting control regions (ICRs) and enhancers within imprinted loci in an allele-...

  5. Laf4/Aff3 is required for normal neuronal migration OmicsDI

    ID: E-MTAB-2520

    Date Released: 07-03-2014

    Description: The aim of this study was to investigate the function of Laf4 in the brain by focusing on its role in the developing cortex. By manipulating expressio...

  6. Laf4/Aff3 is required for normal neuronal migration ArrayExpress

    ID: E-MTAB-2520

    Description: The aim of this study was to investigate the function of Laf4 in the brain by focusing on its role in the developing cortex. By manipulating expressio...

  7. The SEC family of RNA Polymerase II elongation factors: gene target specificity and transcriptional output BioProject

    ID: PRJNA149901

    Keywords: Other

    Access Type: download

    dataset.description: C-L2) and SEC-like 3 (SEC-L3) containing AFF2 and AFF3 in association with P-TEFb, ENL, and AF9. The SEC family members demonstrate high levels of Pol II CTD kinase activity, however, only SEC is required for the proper induction of the HSP70 gene upon stress. Genome-wide mRNA-seq analyses demonstrate that SEC-L2-3 control the expression of different subsets of genes, while AFF4/SEC plays a more dominant role in rapid gene expression in cells. MYC i...
  8. The SEC family of RNA Polymerase II elongation factors: gene target specificity and transcriptional output ArrayExpress

    ID: E-GEOD-34097

    Description: C-L2) and SEC-like 3 (SEC-L3) containing AFF2 and AFF3 in association with P-TEFb, ENL, and AF9. The SEC family members demonstrate high levels of Pol II CTD kinase activity, however, only SEC is required for the proper induction of the HSP70 gene upon stress. Genome-wide mRNA-seq analyses demonstrate that SEC-L2-3 control the expression of different subsets of genes, while AFF4/SEC plays a more dominant role in rapid gene expression in cells. MYC i...

  9. The SEC family of RNA Polymerase II elongation factors: gene target specificity and transcriptional output OmicsDI

    ID: E-GEOD-34097

    Date Released: 05-04-2014

    Description: C-L2) and SEC-like 3 (SEC-L3) containing AFF2 and AFF3 in association with P-TEFb, ENL, and AF9. The SEC family members demonstrate high levels of Pol II CTD kinase activity, however, only SEC is required for the proper induction of the HSP70 gene upon stress. Genome-wide mRNA-seq analyses demonstrate that SEC-L2-3 control the expression of different subsets of genes, while AFF4/SEC plays a more dominant role in rapid gene expression in cells. MYC i...

  10. Genetic Loci that Regulate Ectopic Calcification in Response to Knee Trauma in LG/J by SM/J Advanced Intercross Mice OmicsDI

    ID: E-GEOD-64793

    Date Released: 01-17-2015

    Description: n LG/J and SM/J. Correlation analysis showed that Aff3, Fam81a, Syn3, and Ank were correlated with synovial calcification. Our findings of multiple genetic loci affecting the phenotype suggest the involvement of multiple genes contributing to its pathogenesis. We collected tissue lysates from the formalin-fixed paraffin-embedded sections from mouse knee joints and analyzed the expression of several genes by Affymetrix QuantiGene Plex assay....

  11. Genetic Loci that Regulate Ectopic Calcification in Response to Knee Trauma in LG/J by SM/J Advanced Intercross Mice ArrayExpress

    ID: E-GEOD-64793

    Description: n LG/J and SM/J. Correlation analysis showed that Aff3, Fam81a, Syn3, and Ank were correlated with synovial calcification. Our findings of multiple genetic loci affecting the phenotype suggest the involvement of multiple genes contributing to its pathogenesis. We collected tissue lysates from the formalin-fixed paraffin-embedded sections from mouse knee joints and analyzed the expression of several genes by Affymetrix QuantiGene Plex assay....

  12. Genetic Loci that Regulate Ectopic Calcification in Response to Knee Trauma in LG/J by SM/J Advanced Intercross Mice BioProject

    ID: PRJNA271887

    Keywords: Other

    Access Type: download

    dataset.description: n LG/J and SM/J. Correlation analysis showed that Aff3, Fam81a, Syn3, and Ank were correlated with synovial calcification. Our findings of multiple genetic loci affecting the phenotype suggest the involvement of multiple genes contributing to its pathogenesis. Overall design: We collected tissue lysates from the formalin-fixed paraffin-embedded sections from mouse knee joints and analyzed the expression of several genes by Affymetrix QuantiGene Plex assay....

Displaying 12 of 12 results for "AFF3"